Plasma Fibrinogen Qualification as a Drug Development Tool in COPD: Perspective of the COPD Biomarker Qualification Consortium.

Autor: Miller, Bruce E., Tal-Singer, Ruth, Rennard, Stephen I., Furtwaengler, Armin, Leidy, Nancy, Lowings, Michael, Martin, Ubaldo J., Martin, Thomas, Merrill, Debora D., Snyder, Jeffrey, Walsh, John, Mannino, David M.

Publikováno v: American Journal of Respiratory & Critical Care Medicine; 3/15/2016, Vol. 193 Issue 6, p1-86, 123p, 1 Diagram, 21 Charts, 51 Graphs

Plasma Fibrinogen as a Biomarker for Mortality and Hospitalized Exacerbations in People with COPD.

Autor: Mannino DM; Department of Preventive Medicine and Environmental Health, University of Kentucky, College of Public Health, Lexington., Tal-Singer R; Respiratory Therapy Area Unit, GlaxoSmithKline, Philadelphia, Pennsylvania., Lomas DA; Wolfson Institute for Biomedical Research, University College London, United Kingdom., Vestbo J; Department of Respiratory Medicine, Odense University Hospital & University of Southern Denmark, Odense, Denmark, and Manchester Academic Health Science Centre, University of Manchester, United Kingdom., Graham Barr R; Department of Medicine, Department of Epidemiology, Columbia University Medical Center, New York, New York., Tetzlaff K; Therapeutic Area Respiratory Diseases, Boehringer Ingelheim Pharma GmbH Co KG, Ingelheim, Germany, and Department of Sports Medicine, Medical Clinic V, University of Tuebingen, Germany., Lowings M; Global Regulatory Affairs, GlaxoSmithKline Research and Development, Middlesex, United Kingdom., Rennard SI; Division of Pulmonary, Critical Care, Sleep and Allergy, University of Nebraska Medical Center, Omaha., Snyder J; Regulatory Affairs, Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, Connecticut., Goldman M; Global Medicine Development, AstraZeneca LP, Wilmington, Delaware., Martin UJ; Global Medicine Development, AstraZeneca LP, Wilmington, Delaware., Merrill D; COPD Foundation, Washington, D.C., Martin AL; Health Economics and Epidemiology, Evidera, Lexington, Massachusetts., Simeone JC; Health Economics and Epidemiology, Evidera, Lexington, Massachusetts., Fahrbach K; Health Economics and Epidemiology, Evidera, Lexington, Massachusetts., Murphy B; Health Economics and Epidemiology, Evidera, Lexington, Massachusetts., Leidy N; Health Economics and Epidemiology, Evidera, Lexington, Massachusetts., Miller B; Respiratory Therapy Area Unit, GlaxoSmithKline, Philadelphia, Pennsylvania.

Publikováno v: Chronic obstructive pulmonary diseases (Miami, Fla.) [Chronic Obstr Pulm Dis] 2015; Vol. 2 (1), pp. 23-34.