Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Lowell Reynolds"'
Publikováno v:
Pain Practice. 15:554-563
Objectives Breakthrough cancer pain (BTCP) is associated with decreased satisfaction with around-the-clock opioid therapy. This analysis examined patient satisfaction with fentanyl sublingual spray for BTCP during the open-label titration period of a
Autor:
Richard Rauck, Lowell Reynolds, Jonathan Geach, Neha Parikh, Janet Bull, Larry Dillaha, Morris Scherlis, Lisa Stearns
Publikováno v:
Current Medical Research and Opinion. 28:859-870
A number of transmucosal fentanyl formulations have been developed for the management of breakthrough cancer pain (BTCP). Sublingual delivery of fentanyl, formulated as fentanyl sublingual spray, offers the potential for more rapid and greater absorp
Autor:
Raymond S. Sinatra, Jonathan S. Jahr, Eugene R. Viscusi, JD Mike A. Royal Md, Scott B. Groudine, James B. Breitmeyer, Lowell Reynolds
Publikováno v:
Pain Practice. 12:357-365
Background and Methods: From the time that Sinatra et al. (Anesthesiology. 2005;102:822) was published to FDA apaproval of intravenous (IV) acetaminophen, an expanded analysis of the original raw study data became necessary for the regulatory submiss
Publikováno v:
Anesthesia & Analgesia. 102:188-194
An iontophoretic fentanyl HCl patient-activated transdermal system (fentanyl HCl PATS) is under development for the treatment of acute postoperative pain. The fentanyl HCl PATS is a needle-free, credit card-sized, preprogrammed system that is applied
Autor:
Scott B. Groudine, Raymond S. Sinatra, Jonathan S. Jahr, Catherine Payen-Champenois, Eugene R. Viscusi, Lowell Reynolds
Publikováno v:
Anesthesiology. 102:822-831
Background Intravenous acetaminophen injection (paracetamol) is marketed in Europe for the management of acute pain. A repeated-dose, randomized, double-blind, placebo-controlled, three-parallel group study was performed to evaluate the analgesic eff
Autor:
Steven G. Charapata, Everett Heinze, Nathaniel P. Katz, Dennis M Fisher, Richard Rauck, Russell K. Portenoy, Stuart DuPen, Mark S. Wallace, Lowell Reynolds, Lynn R. Webster
Publikováno v:
Pain. 110:182-188
Sufentanil, a potent mu-opioid agonist, historically has not been been given systemically to treat chronic pain. An implantable, fixed-rate osmotic pump that delivers sufentanil subcutaneously is being developed for this purpose. In that transdermal
Autor:
Lowell Reynolds, Robert K Hoo, Kenneth M. Verburg, Janine North, Robert J Brill, David P. Recker
Publikováno v:
Journal of Pain and Symptom Management. 25:133-141
This multicenter, randomized, double-blind, placebo-controlled study evaluated the analgesic efficacy and opioid-sparing effects of valdecoxib, a potent COX-2 specific inhibitor, in patients undergoing knee replacement. Patients received morphine by
Publikováno v:
Best Practice & Research Clinical Anaesthesiology. 16:651-665
The three-step analgesic ladder approach developed by the World Health Organization works well in treating the vast majority (70-90%) of patients suffering from pain related to cancer. In those patients who do not get pain relief by this three-step a
Publikováno v:
Anesthesiology. 87:1486-1493
Background Hemodilution with diaspirin crosslinked hemoglobin (DCLHb) ameliorates occlusive cerebral ischemia. However, subarachnoid hemoglobin has been implicated as a cause of cerebral hypoperfusion. The effect of intravenous DCLHb on cerebral perf
Publikováno v:
Neurosurgery. 37:742-749
An investigation was performed to compare the cerebral protective properties of etomidate, isoflurane, and thiopental. In separate groups of spontaneously hypertensive rats, etomidate, isoflurane, or thiopental was administered to achieve and maintai