Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Lowell M. Greenbaum"'
Publikováno v:
Biology of Reproduction. 47:945-951
Ovulation has been noted for some time to bear a remarkable similarity to an inflammatory response. One of the principal components that is activated and helps mediate the events during an inflammatory response is the kinin system. Therefore, the pur
Publikováno v:
Endocrinology. 136(1)
Bradykinin is a potent inducer of uterine smooth muscle contractions in rodents and primates. Hence, the purpose of the present study was to characterize the various components of the kinin system in the plasma, uterus, hypothalamus, and anterior pit
Publikováno v:
Biochemical pharmacology. 46(9)
T-Kinin (Ile-Ser-bradykinin) is unique to the rat. This study characterizes the receptors involved in T-kinin activity on both the intact isolated rat uterus and membrane receptor preparations of the rat uterus. The results show that T-kinin acts thr
Publikováno v:
BMC Physiology. 2:7
Background Previous work by our group and others has implicated a role for kinins in the ovulatory process. The purpose of the present study was to elucidate whether endogenous progesterone, which is an intraovarian regulator of ovulation, might be r
Publikováno v:
Agents and Actions. 8:80-84
Publikováno v:
Agents and Actions. 9:265-274
Leukokinin-H, a pharmacologically active peptide, has been isolated from human ascites fluid following its generation in vitro at acid pH. The peptide has a molecular weight of approximately 2500. The partial sequence of Leu-Ala-Tyr-Thr — was obtai
Autor:
Lowell M. Greenbaum
Publikováno v:
Dental Clinics of North America. 22:47-50
Autor:
Lowell M. Greenbaum, Gloria Semente
Publikováno v:
JNCI: Journal of the National Cancer Institute. 59:259-262
The effect of pepstatin on the kinetics of ascitic fluid accumulation in L1210 tumor-bearing mice (DBA/2) was observed. Following inoculation of 1.5x10(6) tumor cells, untreated mice reached a peak of fluid accumulation on day 6 and remained at this
Publikováno v:
Experimental Biology and Medicine. 163:258-263
SummaryThis is the first demonstration that pepstatin levels following i.p. injection may be reached which are totally inhibitory to cathepsin D contained in the lung. Thus an animal model has been created, which is devoid of cathepsin D as demonstra
Autor:
Lowell M. Greenbaum, Steven Roffman
Publikováno v:
Biochemical Pharmacology. 28:1043-1050
Leukokininogen, the protein precursor of the vasoactive polypeptide leukokinin-H, has been isolated from human ovarian carcinoma ascites. A homogeneous preparation was achieved after a procedure consisting of ammonium sulfate fractionation, gel filtr