Zobrazeno 1 - 10
of 201
pro vyhledávání: '"Lowell L. Hart"'
Autor:
Costanza Paoletti, Meredith M. Regan, Samuel M. Niman, Emily M. Dolce, Elizabeth P. Darga, Minetta C. Liu, P. Kelly Marcom, Lowell L. Hart, John W. Smith, Karen L. Tedesco, Eitan Amir, Ian E. Krop, Angela M. DeMichele, Pamela J. Goodwin, Margaret Block, Kimberly Aung, Martha E. Brown, Robert T. McCormack, Daniel F. Hayes
Publikováno v:
npj Breast Cancer, Vol 7, Iss 1, Pp 1-9 (2021)
Abstract Circulating tumor cells (CTC) are prognostic in metastatic breast cancer (MBC). The CTC-endocrine therapy index (CTC-ETI), consisting of CTC-ER (estrogen receptor), BCL2, human epidermal growth factor receptor (HER2), and Ki67 expression, mi
Externí odkaz:
https://doaj.org/article/a4591a6d3a9d4069a97a9133183bb04c
Autor:
Jesus G. Berdeja, Lowell L. Hart, Joseph R. Mace, Edward R. Arrowsmith, James H. Essell, Rami S. Owera, John D. Hainsworth, Ian W. Flinn
Publikováno v:
Haematologica, Vol 100, Iss 5 (2015)
The purpose of this study was to assess the safety and efficacy of the combination of panobinostat and carfilzomib in patients with relapsed/refractory multiple myeloma. Patients with multiple myeloma who had relapsed after at least one prior treatme
Externí odkaz:
https://doaj.org/article/1365294a8f194bb98504171d20ca0bd9
Autor:
Jasgit C. Sachdev, Hagop Youssoufian, Jason M. Summa, Stephen E. Zale, Donald M. Parsons, Susan C. Low, Lowell L. Hart, Howard A. Burris, Patricia M. LoRusso, Alain C. Mita, Glen J. Weiss, Ramesh K. Ramanathan, Monica M. Mita, Daniel D. Von Hoff
Supplemental Section for Resubmission - Clean Version
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3aa296a894ca08020071eff1789db066
https://doi.org/10.1158/1078-0432.22457688
https://doi.org/10.1158/1078-0432.22457688
Autor:
Jennifer A. Low, Gordon L. Bray, Richard A. Graham, Robert L. Yauch, Howard M. Mackey, Mark M. Zalupski, Mary F. Mulcahy, Robert C. Hermann, Ira Gore, Irfan Firdaus, Lowell L. Hart, Johanna C. Bendell, Jordan Berlin
PDF file - 33K, Estimated maximal concentration (Cmax) and total area under the concentration-time curve (AUClast) of irinotecan (and metabolites SN-38 and SN-38G) with and without vismodegib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04b2a6e969d7ebf392680c04fd803180
https://doi.org/10.1158/1078-0432.22445865.v1
https://doi.org/10.1158/1078-0432.22445865.v1
Autor:
Jasgit C. Sachdev, Hagop Youssoufian, Jason M. Summa, Stephen E. Zale, Donald M. Parsons, Susan C. Low, Lowell L. Hart, Howard A. Burris, Patricia M. LoRusso, Alain C. Mita, Glen J. Weiss, Ramesh K. Ramanathan, Monica M. Mita, Daniel D. Von Hoff
Figure S2 displays a graph of the plasma concentrations of total docetaxel for patients dosed with 60/mg/m2 of BIND-014 on the Q3W schedule.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79557d645d1deaff8bf07da24d81755c
https://doi.org/10.1158/1078-0432.22457685.v1
https://doi.org/10.1158/1078-0432.22457685.v1
Autor:
Jennifer A. Low, Gordon L. Bray, Richard A. Graham, Robert L. Yauch, Howard M. Mackey, Mark M. Zalupski, Mary F. Mulcahy, Robert C. Hermann, Ira Gore, Irfan Firdaus, Lowell L. Hart, Johanna C. Bendell, Jordan Berlin
PDF file - 25K, A comparison of serum concentrations of bevacizumab with and without vismodegib co-treatment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44bd20ab21ff0722fc5839feb51cd58c
https://doi.org/10.1158/1078-0432.22445859
https://doi.org/10.1158/1078-0432.22445859
Autor:
Jennifer A. Low, Gordon L. Bray, Richard A. Graham, Robert L. Yauch, Howard M. Mackey, Mark M. Zalupski, Mary F. Mulcahy, Robert C. Hermann, Ira Gore, Irfan Firdaus, Lowell L. Hart, Johanna C. Bendell, Jordan Berlin
PDF file - 57K, A summary of primer/probes used for qRT-PCR profiling of Hh pathway genes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54b4e0a40936477e3510849a4be74ccb
https://doi.org/10.1158/1078-0432.22445853
https://doi.org/10.1158/1078-0432.22445853
Autor:
Jennifer A. Low, Gordon L. Bray, Richard A. Graham, Robert L. Yauch, Howard M. Mackey, Mark M. Zalupski, Mary F. Mulcahy, Robert C. Hermann, Ira Gore, Irfan Firdaus, Lowell L. Hart, Johanna C. Bendell, Jordan Berlin
Purpose: Vismodegib, a Hedgehog pathway inhibitor, has preclinical activity in colorectal cancer (CRC) models. This trial assessed the efficacy, safety, and pharmacokinetics of adding vismodegib to first-line treatment for metastatic CRC (mCRC).Exper
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::443cdb742525f6999d7cda631cb7855c
https://doi.org/10.1158/1078-0432.c.6520578.v1
https://doi.org/10.1158/1078-0432.c.6520578.v1
Autor:
Jasgit C. Sachdev, Hagop Youssoufian, Jason M. Summa, Stephen E. Zale, Donald M. Parsons, Susan C. Low, Lowell L. Hart, Howard A. Burris, Patricia M. LoRusso, Alain C. Mita, Glen J. Weiss, Ramesh K. Ramanathan, Monica M. Mita, Daniel D. Von Hoff
Purpose: First-in-human phase I trial to determine the safety, pharmacokinetics, and antitumor activity of BIND-014, a novel, tumor prostate-specific membrane antigen (PSMA)–targeted nanoparticle, containing docetaxel.Experimental Design: Patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a20f520721801b1c85c0a95c70af1420
https://doi.org/10.1158/1078-0432.c.6523653.v1
https://doi.org/10.1158/1078-0432.c.6523653.v1
Autor:
Jennifer A. Low, Gordon L. Bray, Richard A. Graham, Robert L. Yauch, Howard M. Mackey, Mark M. Zalupski, Mary F. Mulcahy, Robert C. Hermann, Ira Gore, Irfan Firdaus, Lowell L. Hart, Johanna C. Bendell, Jordan Berlin
PDF file - 24K, A comparison of vismodegib steady-state plasma concentrations (Css) between patients receiving FOLFOX and FOLFIRI
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edcdd94766b86dbb07f1d39e79590386
https://doi.org/10.1158/1078-0432.22445871
https://doi.org/10.1158/1078-0432.22445871