Zobrazeno 1 - 10
of 152
pro vyhledávání: '"Lowell E. Hokin"'
Autor:
Lowell E. Hokin, John F. Dixon
Publikováno v:
Proceedings of the National Academy of Sciences. 95:8363-8368
We previously reported that lithium stimulated extracellular glutamate accumulation in monkey and mouse cerebrocortical slices. We report here that this is caused by lithium-induced inhibition of glutamate uptake into the slice. Glutamate release was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf5a7adeec1799b2ae6600e33343a8c0
https://doi.org/10.1073/pnas.95.14.8363
https://doi.org/10.1073/pnas.95.14.8363
Publikováno v:
Advances in Enzyme Regulation. 36:245-264
Lithium has a biphasic effect on the agonist-dependent accumulation of Ins(1,4,5)P3 in human neuroblastoma SH-SY5Y cells. These effects consist of a transient reduction, followed by a long-lasting increase in Ins(1,4,5)P3 as compared to controls. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38e52e6bed2e015c3f59d28d79b861e2
https://doi.org/10.1016/0065-2571(95)00022-4
https://doi.org/10.1016/0065-2571(95)00022-4
Publikováno v:
Proceedings of the National Academy of Sciences. 91:8358-8362
Beginning at therapeutic concentrations (1-1.5 mM), the anti-manic-depressive drug lithium stimulated the release of glutamate, a major excitatory neurotransmitter in the brain, in monkey cerebral cortex slices in a time- and concentration-dependent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1649d7b7e14d06751fb8d31effbd34b
https://doi.org/10.1073/pnas.91.18.8358
https://doi.org/10.1073/pnas.91.18.8358
Publikováno v:
Journal of Histochemistry & Cytochemistry. 40:555-562
We used in situ hybridization histochemistry with synthetic oligonucleotide probes to localize the mRNAs encoding the alpha 2- and beta-mRNAs of Na,K-ATPase during development of the brine shrimp Artemia. The mRNAs of the alpha 2- and beta-subunit we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e12843115c497d008910ccfcb18d0ff8
https://doi.org/10.1177/40.4.1313064
https://doi.org/10.1177/40.4.1313064
Publikováno v:
Journal of Neurochemistry. 58:1079-1086
The accumulation of inositol polyphosphates in the cerebellum in response to agonists has not been demonstrated. Guinea pig cerebellar slices prelabeled with [3H]inositol showed the following increases in response to 1 mM serotonin: At 15 s, there wa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dadfda57e282d5ddc68d0801fc5be85
https://doi.org/10.1111/j.1471-4159.1992.tb09365.x
https://doi.org/10.1111/j.1471-4159.1992.tb09365.x
Publikováno v:
Journal of Histochemistry & Cytochemistry. 39:1455-1460
Developing brine shrimp are a good experimental model for study of gene expression during development. Development is initiated on suspension of brine shrimp cysts in seawater. Only 48 hr are required for progression from cyst to the larval stage. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c8cc6a9876490b5f0c2161dc38154d1
https://doi.org/10.1177/39.11.1655875
https://doi.org/10.1177/39.11.1655875
Autor:
Lowell E. Hokin, Mabel R. Hokin
Publikováno v:
Ciba Foundation Symposium - The Exocrine Pancreas: Normal and Abnormal Functions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b0f6ee98f48388b8223fa6aec05d915d
https://doi.org/10.1002/9780470719268.ch10
https://doi.org/10.1002/9780470719268.ch10
Autor:
Lowell E. Hokin, John F. Dixon
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 94(9)
Valproic acid and lithium are effective antibipolar drugs. We recently showed that lithium stimulated the release of glutamate in monkey and mouse cerebral cortex slices, which, through activation of the N -methyl- d -aspartate receptor, increased ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b36add01bf0cae3402354e10523d0cf
https://pubmed.ncbi.nlm.nih.gov/9114064
https://pubmed.ncbi.nlm.nih.gov/9114064
Autor:
Lowell E. Hokin
Publikováno v:
myo-Inositol Phosphates, Phosphoinositides, and Signal Transduction ISBN: 9781461380078
The discovery of the “phosphoinositide effect” arose out of an accidental observation over 40 years ago. The details of this discovery have been reviewed (Hokin, 1987; Hokin and Hokin-Neaverson, 1989). This chapter deals with studies dating up to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5c0c323cac724314eb92d0bed4ff799
https://doi.org/10.1007/978-1-4613-0343-5_1
https://doi.org/10.1007/978-1-4613-0343-5_1
Publikováno v:
The Biochemical journal. 311
In order to approach the molecular mechanism of Li+'s mood-stabilizing action, the effect of Li+ (LiCl) on inositol 1,4,5-trisphosphate [Ins(1,4,5)P3] mass was investigated in human neuroblastoma SH-SY5Y cells, which express muscarinic M3 receptors,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd7bee2749a8f834b2e0bf9d7b03ccdc
https://pubmed.ncbi.nlm.nih.gov/7575458
https://pubmed.ncbi.nlm.nih.gov/7575458