Zobrazeno 1 - 10
of 98
pro vyhledávání: '"Lowell E, Davis"'
Autor:
Samantha Louey, Lowell E. Davis, Sonnet S. Jonker, Divya Soman, Jonathan W. Nelson, James Musso
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 315:R500-R508
Fetal anemia causes rapid and profound changes in cardiac structure and function, stimulating proliferation of the cardiac myocytes, expansion of the coronary vascular tree, and impairing early contraction and relaxation. Although hypoxia-inducible f
Autor:
Juulia Junno, Pasi Ohtonen, A. Roger Hohimer, Heikki Huhta, Juha Rasanen, Tiina Erkinaro, Mervi Haapsamo, Lowell E. Davis, Ganesh Acharya
Publikováno v:
Experimental Physiology. 103:58-67
Fetal aortic isthmus (AoI) allows communication between left (LV) and right (RV) ventricular outputs and represents arterial watershed between the brachiocephalic (brain) and subdiaphragmatic (placenta) circulations. To understand the capability of A
Autor:
Juulia Lantto, Ganesh Acharya, Juha Rasanen, Mervi Haapsamo, A. Roger Hohimer, Lowell E. Davis, Hanna-Marja Voipio, Heikki Huhta, Tiina Erkinaro
New findings What is the central question of this study? At near-term gestation, foramen ovale blood flow accounts for a significant proportion of fetal left ventricular output. Can the foramen ovale increase its volume blood flow when right ventricu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b755a1f1922bc493be3dcbcbc5d063ca
http://urn.fi/urn:nbn:fi-fe201903229651
http://urn.fi/urn:nbn:fi-fe201903229651
Autor:
Jonathan R. Lindner, Samantha Louey, Adrienne Wilburn, Lowell E. Davis, Divya Soman, Brian P. Davidson, J. Todd Belcik, George D. Giraud, Sonnet S. Jonker, Tamara Atkinson
Publikováno v:
The Journal of Physiology. 594:6165-6174
Key points In fetuses, chronic anaemia stimulates cardiac growth; simultaneously, blood flow to the heart muscle itself is increased, and reserve blood flow capacity of the coronary vascular bed is preserved. Here we examined functional adaptations o
Autor:
David J. Sahn, A. Roger Hohimer, Juha Rasanen, Stephen M. Langley, Muhammed Ashraf, Lowell E. Davis, Vanessa Rogers, Jason Hashima, Pasi Ohtonen
Publikováno v:
Ultrasound in Medicine & Biology. 41:1020-1028
We investigated the effect of fetal sheep ductus arteriosus occlusion (DO) on the distribution of cardiac output and left and right ventricular function by tissue and pulsed Doppler at baseline; after 15 and 60 min of DO induced with a vascular occlu
Autor:
Heikki, Huhta, Juulia, Junno, Mervi, Haapsamo, Tiina, Erkinaro, Pasi, Ohtonen, Lowell E, Davis, A Roger, Hohimer, Ganesh, Acharya, Juha, Rasanen
Publikováno v:
Experimental physiology. 103(1)
What is the central question of this study? The fetal aortic isthmus has an important physiological role, allowing communication between the left and right ventricular outputs, which are arranged in parallel. Can the aortic isthmus provide unrestrict
Autor:
Juha Rasanen, David J. Sahn, A. Roger Hohimer, Muhammad Ashraf, Olli Vuolteenaho, Jason Hashima, Lowell E. Davis, Leah Bernard
Publikováno v:
Reproductive Sciences. 19:173-180
Fetal chronic anemia causes lengthening of cardiomyocytes. In adults, severe left ventricular overload may lead to irreversible ventricular dysfunction. We hypothesized that in sheep fetuses with chronic anemia, remodeled myocardium would less succes
Autor:
Kent L. Thornburg, Sonnet S. Jonker, Natasha N. Chattergoon, M. Kathryn Giraud, J. Job Faber, Samantha Louey, George D. Giraud, Lowell E. Davis
Publikováno v:
Experimental Physiology. 95:131-139
Chronic anaemia increases the workload of the growing fetal heart, leading to cardiac enlargement. To determine which cellular process increases cardiac mass, we measured cardiomyocyte sizes, binucleation as an index of terminal differentiation, and
Autor:
J. Job Faber, A. Roger Hohimer, Patricia Robertson, Debra F. Anderson, Samantha Louey, Lowell E. Davis, Robert A. Brace
Publikováno v:
Reproductive Sciences. 16:88-93
We designed experiments to allow direct measurement of amniotic fluid volume and continuous measurement of lung liquid production, swallowing, and urine production in fetal sheep. From these values, the rate of intramembranous absorption was calculat
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 291:H2884-H2888
Six singleton fetal sheep of 118–122 days gestational age were instrumented with flow sensors on the brachiocephalic artery, the postductal aorta, and the common umbilical artery and with arterial and venous intravascular catheters. At 125–131 da