Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Lowe Christopher E"'
Autor:
Todd John A, Lowe Christopher E, Clatworthy Menna R, Carr Edward J, Wong Andrew, Vyse Timothy J, Kamesh Lavanya, Watts Richard A, Lyons Paul A, Smith Kenneth GC
Publikováno v:
BMC Medical Genetics, Vol 10, Iss 1, p 22 (2009)
Abstract Background Autoimmune diseases are complex and have genetic and environmental susceptibility factors. The objective was to test the genetic association of systemic lupus erythematosus (SLE) and anti-neutrophil cytoplasmic antibody (ANCA) –
Externí odkaz:
https://doaj.org/article/1b58057ef0004e99b4f8b360a89b8b12
Autor:
Barratt Bryan J, Twells Rebecca, Smith Anne, Walker Neil M, Nutland Sarah, Stevens Helen, Burren Oliver, Lam Alex, Godfrey Lisa, Masters Jennifer, Payne Felicity, Lowe Christopher E, Bailey Rebecca, Smyth Deborah, Smink Luc J, Nejentsev Sergey, Wright Charmain, French Lisa, Chen Yuan, Deloukas Panagiotis, Rogers Jane, Dunham Ian, Todd John A
Publikováno v:
BMC Genetics, Vol 8, Iss 1, p 24 (2007)
Abstract Background In an effort to locate susceptibility genes for type 1 diabetes (T1D) several genome-wide linkage scans have been undertaken. A chromosomal region designated IDDM10 retained genome-wide significance in a combined analysis of the m
Externí odkaz:
https://doaj.org/article/37dd7d5fadb64df7abd0af79d4612388
Autor:
Smink Luc J, Walker Neil M, Burren Oliver, Lam Alex C, Healy Barry C, Nutland Sarah, Bailey Rebecca, Smyth Deborah J, Cooper Jason D, Lowe Christopher E, Taniguchi Hidenori, Wicker Linda S, Todd John A
Publikováno v:
BMC Genetics, Vol 7, Iss 1, p 22 (2006)
Abstract Background Type 1 diabetes (T1D) is a common autoimmune disease resulting from T-cell mediated destruction of pancreatic beta cells. Decay accelerating factor (DAF, CD55), a glycosylphosphatidylinositol-anchored membrane protein, is a candid
Externí odkaz:
https://doaj.org/article/7011c124141642e49bf19ba66e134d25
Autor:
Walker Neil M, Nutland Sarah, Lam Alex C, Dahlman Ingrid, Vella Adrian, Hulme John S, Cooper Jason D, Lowe Christopher E, Holland Kieran, Bailey Rebecca, Maier Lisa M, Payne Felicity, Howson Joanna MM, Smyth Deborah J, Twells Rebecca CJ, Todd John A
Publikováno v:
BMC Medical Genetics, Vol 7, Iss 1, p 20 (2006)
Abstract Background The identification of the HLA class II, insulin (INS), CTLA-4 and PTPN22 genes as determinants of type 1 diabetes (T1D) susceptibility indicates that fine tuning of the immune system is centrally involved in disease development. S
Externí odkaz:
https://doaj.org/article/743bca594e3c4923877ac0ba5cce95e6
Autor:
Lam Alex C, Healy Barry C, Walker Neil M, Hulme John S, Godfrey Lisa, Vella Adrian, Payne Felicity, Cooper Jason D, Lowe Christopher E, Morris Gerard AJ, Lyons Paul A, Todd John A
Publikováno v:
BMC Genetics, Vol 7, Iss 1, p 12 (2006)
Abstract Background The aetiology of the autoimmune disease type 1 diabetes (T1D) involves many genetic and environmental factors. Evidence suggests that innate immune responses, including the action of interferons, may also play a role in the initia
Externí odkaz:
https://doaj.org/article/bc4f5202af8c401ebe0bee4c48d8d622
Autor:
Maier, Lisa M., Howson, Joanna M.M., Walker, Neil, Spickett, Gavin P., Jones, Richard W., Ring, Susan M., McArdle, Wendy L., Lowe, Christopher E., Bailey, Rebecca, Payne, Felicity, Todd, John A., Strachan, David P.
Publikováno v:
In The Journal of Allergy and Clinical Immunology 2006 117(6):1306-1313
Autor:
Maier, Lisa M.1,2, Lowe, Christopher E.3, Cooper, Jason3, Downes, Kate3, Anderson, David E.1, Severson, Christopher1, Clark, Pamela M.3, Healy, Brian4,5, Walker, Neil3, Aubin, Cristin2, Oksenberg, Jorge R.6, Hauser, Stephen L.6, Compston, Alistair7, Sawcer, Stephen7, de Jager, Philip L.1,2,8, Wicker, Linda S.3, Todd, John A.3, Hafler, David A.1,2 hafler@broad.mit.edu
Publikováno v:
PLoS Genetics. Jan2009, Vol. 5 Issue 1, p1-8. 8p. 2 Charts, 1 Graph.
Autor:
Lowe, Christopher E.1, Cooper, Jason D.1, Brusko, Todd2, Walker, Neil M.1, Smyth, Deborah J.1, Bailey, Rebecca1, Bourget, Kirsi1, Plagnol, Vincent1, Field, Sarah1, Atkinson, Mark2, Clayton, David G.1, Wicker, Linda S.1, Todd, John A.1 john.todd@cimr.cam.ac.uk
Publikováno v:
Nature Genetics. Sep2007, Vol. 39 Issue 9, p1074-1082. 9p. 1 Diagram, 4 Charts, 2 Graphs.
Autor:
Taniguchi, Hidenori1 htaniguc@geriat.med.osaka.u.ac.jp, Lowe, Christopher E1 chris.lowe@cimr.cam.ac.uk, Cooper, Jason D1 jason.cooper@cimr.cam.ac.uk, Smyth, Deborah J1 debbie.smyth@cimr.cam.ac.uk, Bailey, Rebecca1 rebecca.bailey@cimr.cam.ac.uk, Nutland, Sarah1 sarah.nutland@cimr.cam.ac.uk, Healy, Barry C1 barry.healy@cimr.cam.ac.uk, Lam, Alex C1 alex.lam@bbsrc.ac.uk, Burren, Oliver1 oliver.burren@cimr.cam.ac.uk, Walker, Neil M1 neil.walker@cimr.cam.ac.uk, Smink, Luc J1 luc.smink@cimr.cam.ac.uk, Wicker, Linda S1 linda.wicker@cimr.cam.ac.uk, Todd, John A1 john.todd@cimr.cam.ac.uk
Publikováno v:
BMC Genetics. 2006, Vol. 7, p22-9. 9p. 1 Color Photograph, 3 Charts.
Autor:
Morris, Gerard AJ1 gmorris@hsph.harvard.edu, Lowe, Christopher E1 chris.lowe@cimr.cam.ac.uk, Cooper, Jason D1 jason.cooper@cimr.cam.ac.uk, Payne, Felicity1 fp1@sanger.ac.uk, Vella, Adrian1 adrian.vella@mayo.edu, Godfrey, Lisa1 lisa_monique18@hotmail.com, Hulme, John S1 jh349@cam.ac.uk, Walker, Neil M1 neil.walker@cimr.cam.ac.uk, Healy, Barry C1 barry.healy@cimr.cam.ac.uk, Lam, Alex C1 alex.lam@bbsrc.ac.uk, Lyons, Paul A1 pal34@cam.ac.uk;, Todd, John A1 john.todd@cimr.cam.ac.uk
Publikováno v:
BMC Genetics. 2006, Vol. 7, p12-7. 7p. 1 Chart, 1 Graph.