Zobrazeno 1 - 10
of 671
pro vyhledávání: '"Lowden P"'
Autor:
Djibril M. Ba, Vernon M. Chinchilli, Anna M. Cozzi, David P. Bradley, Ariana R. Pichardo-Lowden
Publikováno v:
Frontiers in Clinical Diabetes and Healthcare, Vol 4 (2024)
IntroductionDiabetes is a major cause of disease burden with considerable public health significance. While the pancreas plays a significant role in glucose homeostasis, the association between pancreatitis and new onset diabetes is not well understo
Externí odkaz:
https://doaj.org/article/44a5e3e6f74e428cb065421619c6114b
Publikováno v:
Next Materials, Vol 1, Iss 4, Pp 100056- (2023)
This study presents the successful development of a new high γ′ nickel-based superalloy, LW 4280, using laser powder bed fusion. Microstructural analysis revealed the absence of γ′ precipitates in the as-built condition. A designed sub-solvus h
Externí odkaz:
https://doaj.org/article/f99c7ceb3e7e475a988e91f2bc90bd6d
Akademický článek
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Akademický článek
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Publikováno v:
Diabetology, Vol 4, Iss 1, Pp 86-92 (2023)
Sodium-glucose cotransporter-2 (SGLT2) inhibitors are emerging as an important therapy not only for type 2 diabetes (T2DM), but also for heart disease and kidney disease. As these medicines gain acceptance, the number of hospitalized patients receivi
Externí odkaz:
https://doaj.org/article/476a7e9dca7a41be826d42b982eba165
Autor:
Kimberly Goodspeed, Daniel Horton, Andrea Lowden, Peter V. Sguigna, Timothy Booth, Zhiyue J. Wang, Veronica Bordes Edgar
Publikováno v:
JIMD Reports, Vol 63, Iss 5, Pp 425-433 (2022)
Abstract Aspartylglucosaminuria (AGU) is a rare lysosomal storage disorder that causes stagnation of development in adolescence and neurodegeneration in early adulthood. Precision therapies, including gene transfer therapy, are in development with a
Externí odkaz:
https://doaj.org/article/51d90e9cc24f421e9a38d66848bac1f3
Autor:
Kimberly A. Jett, Zakery N. Baker, Amzad Hossain, Aren Boulet, Paul A. Cobine, Sagnika Ghosh, Philip Ng, Orhan Yilmaz, Kris Barreto, John DeCoteau, Karen Mochoruk, George N. Ioannou, Christopher Savard, Sai Yuan, Osama H.M.H. Abdalla, Christopher Lowden, Byung-Eun Kim, Hai-Ying Mary Cheng, Brendan J. Battersby, Vishal M. Gohil, Scot C. Leary
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 1 (2023)
Signaling circuits crucial to systemic physiology are widespread, yet uncovering their molecular underpinnings remains a barrier to understanding the etiology of many metabolic disorders. Here, we identified a copper-linked signaling circuit activate
Externí odkaz:
https://doaj.org/article/018c1e9c28eb4a92a02a5abcb7afd106
Autor:
Rachel Lowden, Steve Turner
Publikováno v:
ERJ Open Research, Vol 8, Iss 4 (2022)
Acute exacerbations are common in children and potentially preventable. Currently, a past exacerbation is the best predictor of a future exacerbation. We undertook a systematic review of the literature describing the relationship between past and fut
Externí odkaz:
https://doaj.org/article/fc2191952a03466b85072daa638c9cbb
Autor:
Eric D. Moyer, Erik B. Lehman, Matthew D. Bolton, Jennifer Goldstein, Ariana R. Pichardo-Lowden
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Stress hyperglycemia (SH) is a manifestation of altered glucose metabolism in acutely ill patients which worsens outcomes and may represent a risk factor for diabetes. Continuity of care can assess this risk, which depends on quality of hosp
Externí odkaz:
https://doaj.org/article/d8dba1f44a114445992269e9979b0113
Autor:
Hamish D. Morrison, Jonathan Cleaver, Natasha Lander, Philippa Lowden, Kate Hale, Kanchan Sharma, James Stevens
Publikováno v:
eJHaem, Vol 2, Iss 4, Pp 842-844 (2021)
Externí odkaz:
https://doaj.org/article/67671c3942d14609aaede3b5bebc23f5