Li-Fraumeni Syndrome-Associated Dimer-Forming Mutant p53 Promotes Transactivation-Independent Mitochondrial Cell Death.

Autor: Choe JH; Department of Biological Sciences, Columbia University, New York, New York., Kawase T; Department of Biological Sciences, Columbia University, New York, New York.; Astellas Pharma Inc., Tsukuba, Ibaraki, Japan., Xu A; Department of Integrative Biology and Pharmacology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas., Guzman A; Department of Biological Sciences, Columbia University, New York, New York., Obradovic AZ; Columbia Center for Translational Immunology, Department of Medicine, Columbia University Medical Center, New York, New York.; Department of Systems Biology, Columbia University, New York, New York., Low-Calle AM; Department of Biological Sciences, Columbia University, New York, New York., Alaghebandan B; Department of Biological Sciences, Columbia University, New York, New York., Raghavan A; Department of Biological Sciences, Columbia University, New York, New York., Long K; Department of Biological Sciences, Columbia University, New York, New York., Hwang PM; Cardiovascular Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland., Schiffman JD; Department of Pediatrics, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah.; Peel Therapeutics, Inc., Salt Lake City, Utah., Zhu Y; Department of Biological Sciences, St. John's University, New York, New York., Zhao R; Department of Integrative Biology and Pharmacology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas., Lee DF; Department of Integrative Biology and Pharmacology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas.; The University of Texas MD Anderson Cancer Center UTHealth Houston Graduate School of Biomedical Sciences, Houston, Texas.; Center for Precision Health, School of Biomedical Informatics, The University of Texas Health Science Center at Houston, Houston, Texas.; Center for Stem Cell and Regenerative Medicine, The Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases, The University of Texas Health Science Center at Houston, Houston, Texas., Katz C; Department of Biological Sciences, Columbia University, New York, New York., Prives C; Department of Biological Sciences, Columbia University, New York, New York.

Publikováno v: Cancer discovery [Cancer Discov] 2023 May 04; Vol. 13 (5), pp. 1250-1273.

Wild-type and cancer-related p53 proteins are preferentially degraded by MDM2 as dimers rather than tetramers.

Autor: Katz C; Department of Biological Sciences, Columbia University, New York, New York 10027, USA., Low-Calle AM; Department of Biological Sciences, Columbia University, New York, New York 10027, USA., Choe JH; Department of Biological Sciences, Columbia University, New York, New York 10027, USA., Laptenko O; Department of Biological Sciences, Columbia University, New York, New York 10027, USA., Tong D; Department of Biological Sciences, Columbia University, New York, New York 10027, USA., Joseph-Chowdhury JN; Department of Biological Sciences, Columbia University, New York, New York 10027, USA., Garofalo F; Department of Biological Sciences, Columbia University, New York, New York 10027, USA., Zhu Y, Friedler A; Institute of Chemistry, The Hebrew University of Jerusalem, Givat Ram, Jerusalem 9190401, Israel., Prives C; Department of Biological Sciences, Columbia University, New York, New York 10027, USA.

Publikováno v: Genes & development [Genes Dev] 2018 Mar 01; Vol. 32 (5-6), pp. 430-447. Date of Electronic Publication: 2018 Mar 16.

Study of interferon-β antiviral activity against Herpes simplex virus type 1 in neuron-enriched trigeminal ganglia cultures.

Autor: Low-Calle AM; Grupo de Virologia, Universidad El Bosque, Carrera 9 No. 131 A-02, Edificio de Biblioteca, Laboratorio 205, Bogotá D.C., Colombia. Electronic address: anamalowc@gmail.com., Prada-Arismendy J; Grupo de Virologia, Universidad El Bosque, Carrera 9 No. 131 A-02, Edificio de Biblioteca, Laboratorio 205, Bogotá D.C., Colombia. Electronic address: jpradaarismendy@yahoo.es., Castellanos JE; Grupo de Virologia, Universidad El Bosque, Carrera 9 No. 131 A-02, Edificio de Biblioteca, Laboratorio 205, Bogotá D.C., Colombia; Grupo de Patogénesis Infecciosa, Facultad de Odontología, Universidad Nacional de Colombia, Carrera 30 No. 45-03, Edificio 210 - Oficina 301, Bogotá D.C., Colombia. Electronic address: jecastellanosp@unal.edu.co.

Publikováno v: Virus research [Virus Res] 2014 Feb 13; Vol. 180, pp. 49-58. Date of Electronic Publication: 2013 Dec 24.