Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Lovisa Lundholm"'
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 284, Iss , Pp 117009- (2024)
Purpose: Epidemiological studies show that radon and cigarette smoke interact in inducing lung cancer, but the contribution of nicotine in response to alpha radiation emitted by radon is not well understood. Materials and methods: Bronchial epithelia
Externí odkaz:
https://doaj.org/article/e9d7ed23875d404898c3bc29d5d38570
Autor:
Milagrosa López Riego, Prabodha Kumar Meher, Beata Brzozowska, Pamela Akuwudike, Martin Bucher, Ursula Oestreicher, Lovisa Lundholm, Andrzej Wojcik
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Astronauts travelling in space will be exposed to mixed beams of particle radiation and photons. Exposure limits that correspond to defined cancer risk are calculated by multiplying absorbed doses by a radiation-type specific quality factor
Externí odkaz:
https://doaj.org/article/328759b664b64b5b8a856944e573e791
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Evidence on the impact of chemotherapy on radiotherapy-induced second malignant neoplasms is controversial. We estimated how cisplatin modulates the in vitro response of two normal cell types to fractionated radiation. AHH-1 lymphoblasts and
Externí odkaz:
https://doaj.org/article/2fe9f108a6f14ae4a1aa76ded4416ccd
Autor:
Pamela Akuwudike, Milagrosa López-Riego, Michal Marczyk, Zuzana Kocibalova, Fabian Brückner, Joanna Polańska, Andrzej Wojcik, Lovisa Lundholm
Publikováno v:
Frontiers in Public Health, Vol 11 (2023)
IntroductionExperimental studies complement epidemiological data on the biological effects of low doses and dose rates of ionizing radiation and help in determining the dose and dose rate effectiveness factor.MethodsHuman VH10 skin fibroblasts expose
Externí odkaz:
https://doaj.org/article/5c86d6fb083a4b67b44523363d10d464
Publikováno v:
PLoS ONE, Vol 18, Iss 6, p e0286902 (2023)
DNA double strand breaks (DSBs) are a deleterious form of DNA damage. Densely ionising alpha radiation predominantly induces complex DSBs and sparsely ionising gamma radiation-simple DSBs. We have shown that alphas and gammas, when applied simultaneo
Externí odkaz:
https://doaj.org/article/dff72023ead6420fa5d91ab638f7fca5
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2023)
Externí odkaz:
https://doaj.org/article/929740e26cd44ea4bd037eb8addb0f57
Autor:
Aneta Węgierek-Ciuk, Anna Lankoff, Halina Lisowska, Piotr Kędzierawski, Pamela Akuwudike, Lovisa Lundholm, Andrzej Wojcik
Publikováno v:
Cells, Vol 10, Iss 10, p 2709 (2021)
Gynaecologic cancers are common among women and treatment includes surgery, radiotherapy or chemotherapy, where the last two methods induce DNA damage in non-targeted cells like peripheral blood lymphocytes (PBL). Damaged normal cells can transform l
Externí odkaz:
https://doaj.org/article/f2d8740c4430432d8ba522c714f74062
Autor:
Maja Svetličič, Anton Bomhard, Christoph Sterr, Fabian Brückner, Magdalena Płódowska, Halina Lisowska, Lovisa Lundholm
Publikováno v:
Cells, Vol 9, Iss 5, p 1165 (2020)
Compact chromatin is linked to a poor tumour prognosis and resistance to radiotherapy from photons. We investigated DNA damage induction and repair in the context of chromatin structure for densely ionising alpha radiation as well as its therapeutic
Externí odkaz:
https://doaj.org/article/654549601b954bb086b9c24bda94fbf1
Autor:
Lei Cheng, Beata Brzozowska, Alice Sollazzo, Lovisa Lundholm, Halina Lisowska, Siamak Haghdoost, Andrzej Wojcik
Publikováno v:
PLoS ONE, Vol 13, Iss 10, p e0204068 (2018)
Due to its ability to induce DNA damage in a space and time controlled manner, ionising radiation is a unique tool for studying the mechanisms of DNA repair. The biological effectiveness of ionising radiation is related to the ionisation density whic
Externí odkaz:
https://doaj.org/article/905223f6b7a54633a5a327027f90b32f
Autor:
Milagrosa López-Riego, Magdalena Płódowska, Milena Lis-Zajęcka, Kamila Jeziorska, Sylwia Tetela, Aneta Węgierek-Ciuk, Daniel Sobota, Janusz Braziewicz, Lovisa Lundholm, Halina Lisowska, Andrzej Wojcik
Candidate ionising radiation exposure biomarkers must be validated in humans exposed in vivo. Blood from patients undergoing positron emission tomography - computed tomography scan (PET-CT) and skeletal scintigraphy (scintigraphy) was drawn before (0
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::93a2a24ab0bbc3f3d76d417f18b30c6f
https://doi.org/10.21203/rs.3.rs-2873007/v1
https://doi.org/10.21203/rs.3.rs-2873007/v1