CCNE1 and survival of patients with tubo-ovarian high-grade serous carcinoma: An Ovarian Tumor Tissue Analysis consortium study.

Autor: Kang EY; Department of Pathology and Laboratory Medicine, University of Calgary, Foothills Medical Center, Calgary, Alberta, Canada., Weir A; School of Clinical Medicine, UNSW Medicine and Health, University of NSW Sydney, Sydney, New South Wales, Australia.; Adult Cancer Program, Lowy Cancer Research Centre, University of NSW Sydney, Sydney, New South Wales, Australia.; The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia., Meagher NS; School of Clinical Medicine, UNSW Medicine and Health, University of NSW Sydney, Sydney, New South Wales, Australia.; The Daffodil Centre, The University of Sydney, A Joint Venture With Cancer Council NSW, Sydney, New South Wales, Australia., Farrington K; Department of Pathology and Laboratory Medicine, University of Calgary, Foothills Medical Center, Calgary, Alberta, Canada., Nelson GS; Department of Oncology, Division of Gynecologic Oncology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada., Ghatage P; Department of Oncology, Division of Gynecologic Oncology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada., Lee CH; Department of Pathology and Laboratory Medicine, University of Alberta, Edmonton, Alberta, Canada., Riggan MJ; Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Duke University Medical Center, Durham, North Carolina, USA., Bolithon A; Adult Cancer Program, Lowy Cancer Research Centre, University of NSW Sydney, Sydney, New South Wales, Australia.; School of Women's and Children's Health, Faculty of Medicine and Health, University of NSW Sydney, Sydney, New South Wales, Australia., Popovic G; Stats Central, Mark Wainwright Analytical Centre, University of NSW Sydney, Sydney, New South Wales, Australia., Leung B; Prince of Wales Clinical School, UNSW Medicine and Health, University of NSW Sydney, Sydney, New South Wales, Australia., Tang K; Department of Anatomical Pathology, Prince of Wales Hospital, Sydney, New South Wales, Australia., Lambie N; Canterbury Health Laboratories, Christchurch, New Zealand., Millstein J; Division of Biostatistics, Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, California, USA., Alsop J; Department of Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge, UK., Anglesio MS; Department of Obstetrics and Gynecology, University of British Columbia, Vancouver, British Columbia, Canada.; British Columbia's Gynecological Cancer Research Team (OVCARE), University of British Columbia, BC Cancer, and Vancouver General Hospital, Vancouver, British Columbia, Canada., Ataseven B; Department of Gynecology and Gynecologic Oncology, Evangelische Kliniken Essen-Mitte (KEM), Essen, Germany.; Department of Obstetrics and Gynecology, Ludwig Maximilian University Munich, Munich, Germany., Barlow E; Gynaecological Cancer Centre, Royal Hospital for Women, Sydney, New South Wales, Australia., Beckmann MW; Department of Gynecology and Obstetrics, Comprehensive Cancer Center Erlangen-EMN, Friedrich-Alexander University Erlangen-Nuremberg, University Hospital Erlangen, Erlangen, Germany., Berger J; Division of Gynecologic Oncology, Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA., Bisinotto C; Department of Gynecology and Obstetrics, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil., Bösmüller H; Institute of Pathology and Neuropathology, Tuebingen University Hospital, Tuebingen, Germany., Boros J; Centre for Cancer Research, The Westmead Institute for Medical Research, University of Sydney, Sydney, New South Wales, Australia.; Department of Gynaecological Oncology, Westmead Hospital, Sydney, New South Wales, Australia.; Discipline of Obstetrics and Gynaecology, The University of Sydney, Sydney, New South Wales, Australia., Brand AH; Department of Gynaecological Oncology, Westmead Hospital, Sydney, New South Wales, Australia.; Discipline of Obstetrics and Gynaecology, The University of Sydney, Sydney, New South Wales, Australia., Brooks-Wilson A; Canada's Michael Smith Genome Sciences Centre, BC Cancer, Vancouver, British Columbia, Canada., Brucker SY; Department of Women's Health, Tuebingen University Hospital, Tuebingen, Germany., Carney ME; Department of Obstetrics and Gynecology, John A. Burns School of Medicine, University of Hawaii, Honolulu, Hawaii, USA., Casablanca Y; Uniformed Services of the Health Sciences Gynecologic Cancer Center of Excellence, Bethesda, Maryland, USA., Cazorla-Jiménez A; Pathology Department, Fundación Jiménez Díaz, Madrid, Spain., Cohen PA; Department of Gynaecological Oncology, St John of God Subiaco Hospital, Subiaco, Western Australia, Australia.; Division of Obstetrics and Gynaecology, Medical School, University of Western Australia, Crawley, Western Australia, Australia., Conrads TP; Women's Health Integrated Research Center, Inova Health System, Falls Church, Virginia, USA., Cook LS; Epidemiology, School of Public Health, University of Colorado, Aurora, Colorado, USA.; Community Health Sciences, University of Calgary, Calgary, Alberta, Canada., Coulson P; Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK., Courtney-Brooks M; Division of Gynecologic Oncology, Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA., Cramer DW; Obstetrics and Gynecology Epidemiology Center, Department of Obstetrics and Gynecology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA., Crowe P; Prince of Wales Clinical School, UNSW Medicine and Health, University of NSW Sydney, Sydney, New South Wales, Australia.; Department of Surgery, Prince of Wales Private Hospital, Randwick, New South Wales, Australia., Cunningham JM; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA., Cybulski C; Department of Genetics and Pathology, International Hereditary Cancer Center, Pomeranian Medical University, Szczecin, Poland., Darcy KM; Gynecologic Cancer Center of Excellence, Department of Gynecologic Surgery and Obstetrics, Uniformed Services University of the Health Sciences, Walter Reed National Military Medical Center, Bethesda, Maryland, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc, Bethesda, Maryland, USA., El-Bahrawy MA; Department of Metabolism, Digestion and Reproduction, Imperial College London, Hammersmith Hospital, London, UK., Elishaev E; Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA., Erber R; Institute of Pathology, Comprehensive Cancer Center Erlangen-EMN, Friedrich-Alexander University Erlangen-Nuremberg, University Hospital Erlangen, Erlangen, Germany., Farrell R; Prince of Wales Private Hospital, Randwick, New South Wales, Australia., Fereday S; Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, Victoria, Australia., Fischer A; Institute of Pathology and Neuropathology, Tuebingen University Hospital, Tuebingen, Germany., García MJ; Computational Oncology Group, Structural Biology Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain., Gayther SA; Center for Bioinformatics and Functional Genomics and the Cedars Sinai Genomics Core, Cedars-Sinai Medical Center, Los Angeles, California, USA., Gentry-Maharaj A; MRC Clinical Trials Unit, Institute of Clinical Trials & Methodology, University College London, London, UK., Gilks CB; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada., Grube M; Department of Women's Health, Tuebingen University Hospital, Tuebingen, Germany., Harnett PR; Discipline of Obstetrics and Gynaecology, The University of Sydney, Sydney, New South Wales, Australia.; Crown Princess Mary Cancer Centre, Westmead Hospital, Sydney, New South Wales, Australia., Harrington SP; Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, The University of Kansas Medical Center, Kansas City, Kansas, USA., Harter P; Department of Gynecology and Gynecologic Oncology, Evangelische Kliniken Essen-Mitte (KEM), Essen, Germany.; Department of Gynecology and Gynecological Oncology, HSK, Dr. Horst-Schmidt Klinik, Wiesbaden, Wiesbaden, Germany., Hartmann A; Institute of Pathology, Comprehensive Cancer Center Erlangen-EMN, Friedrich-Alexander University Erlangen-Nuremberg, University Hospital Erlangen, Erlangen, Germany., Hecht JL; Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, USA., Heikaus S; Center for Pathology, Evangelische Kliniken Essen-Mitte, Essen, Germany., Hein A; Department of Gynecology and Obstetrics, Comprehensive Cancer Center Erlangen-EMN, Friedrich-Alexander University Erlangen-Nuremberg, University Hospital Erlangen, Erlangen, Germany., Heitz F; Department of Gynecology and Gynecologic Oncology, Evangelische Kliniken Essen-Mitte (KEM), Essen, Germany.; Department of Gynecology and Gynecological Oncology, HSK, Dr. Horst-Schmidt Klinik, Wiesbaden, Wiesbaden, Germany.; Center for Pathology, Evangelische Kliniken Essen-Mitte, Essen, Germany., Hendley J; Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia., Hernandez BY; University of Hawaii Cancer Center, Honolulu, Hawaii, USA., Polo SH; Medical Oncology Service, Hospital Universitario Funcación Alcorcón, Alcorcón, Spain., Heublein S; Department of Obstetrics and Gynecology, University Hospital Heidelberg, Heidelberg, Germany., Hirasawa A; Department of Clinical Genomic Medicine, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan., Høgdall E; Department of Pathology, Herlev Hospital, University of Copenhagen, Copenhagen, Denmark., Høgdall CK; Department of Gynaecology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark., Horlings HM; Division of Molecular Pathology, The Netherlands Cancer Institute, Amsterdam, The Netherlands., Huntsman DG; Department of Obstetrics and Gynecology, University of British Columbia, Vancouver, British Columbia, Canada.; Department of Molecular Oncology, BC Cancer Research Centre, Vancouver, British Columbia, Canada., Huzarski T; Department of Genetics and Pathology, International Hereditary Cancer Center, Pomeranian Medical University, Szczecin, Poland.; Department of Genetics and Pathology, University of Zielona Gora, Zielona Gora, Poland., Jewell A; Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, The University of Kansas Medical Center, Kansas City, Kansas, USA., Jimenez-Linan M; Department of Histopathology, Addenbrooke's Hospital, Cambridge, UK., Jones ME; Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK., Kaufmann SH; Division of Oncology Research and Department of Molecular Pharmacology & Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota, USA., Kennedy CJ; Centre for Cancer Research, The Westmead Institute for Medical Research, University of Sydney, Sydney, New South Wales, Australia.; Department of Gynaecological Oncology, Westmead Hospital, Sydney, New South Wales, Australia.; Discipline of Obstetrics and Gynaecology, The University of Sydney, Sydney, New South Wales, Australia., Khabele D; Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Washington University in St. Louis, St. Louis, Missouri, USA., Kommoss FKF; Institute of Pathology, Heidelberg University Hospital, Heidelberg, Germany., Kruitwagen RFPM; Department of Obstetrics and Gynecology, Maastricht University Medical Centre, Maastricht, The Netherlands.; GROW - School for Oncology and Reproduction, Maastricht University Medical Center, Maastricht, The Netherlands., Lambrechts D; Department of Human Genetics, Laboratory for Translational Genetics, KU Leuven, Leuven, Belgium.; VIB Center for Cancer Biology, VIB, Leuven, Belgium., Le ND; Cancer Control Research, BC Cancer Agency, Vancouver, British Columbia, Canada., Lener M; International Hereditary Cancer Center, Department of Genetics and Pathology, Pomeranian Medical University in Szczecin, Szczecin, Poland., Lester J; David Geffen School of Medicine, Department of Obstetrics and Gynecology, University of California at Los Angeles, Los Angeles, California, USA., Leung Y; Division of Obstetrics and Gynaecology, Faculty of Health and Medical Sciences, University of Western Australia, Crawley, Western Australia, Australia.; Department of Gynaecological Oncology, King Edward Memorial Hospital, Subiaco, Western Australia, Australia.; Australia New Zealand Gynaecological Oncology Group, Camperdown, Australia., Linder A; Department of Obstetrics and Gynecology, Inst of Clinical Science, Sahlgrenska Center for Cancer Research, University of Gothenburg, Gothenburg, Sweden., Loverix L; Division of Gynecologic Oncology, Department of Gynecology and Obstetrics, Leuven Cancer Institute, Leuven, Belgium., Lubiński J; Department of Genetics and Pathology, International Hereditary Cancer Center, Pomeranian Medical University, Szczecin, Poland., Madan R; Department of Pathology and Laboratory Medicine, The University of Kansas Medical Center, Kansas City, Kansas, USA., Maxwell GL; Inova Health System Women's Service Line, Falls Church, Virginia, USA., Modugno F; Division of Gynecologic Oncology, Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.; Department of Epidemiology, University of Pittsburgh School of Public Health, Pittsburgh, Pennsylvania, USA.; Women's Cancer Research Center, Magee-Womens Research Institute and Hillman Cancer Center, Pittsburgh, Pennsylvania, USA., Neuhausen SL; Department of Population Sciences, Beckman Research Institute of City of Hope, Duarte, California, USA., Olawaiye A; Division of Gynecologic Oncology, Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA., Olbrecht S; Division of Gynecologic Oncology, Department of Gynecology and Obstetrics, Leuven Cancer Institute, Leuven, Belgium., Orsulic S; David Geffen School of Medicine, Department of Obstetrics and Gynecology, University of California at Los Angeles, Los Angeles, California, USA., Palacios J; Department of Pathology, Hospital Ramón y Cajal, Instituto Ramon y Cajal de Investigación Sanitaria (IRyCIS), CIBERONC, Universidad de Alcalá, Madrid, Spain., Pearce CL; Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, Michigan, USA., Pike MC; Department of Epidemiology and Biostatistics, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.; Department of Population Health and Public Health Sciences, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, California, USA., Quinn CM; The Health Precincts Biobank, UNSW Biospecimen Services, Mark Wainwright Analytical Centre, University of NSW Sydney, Sydney, New South Wales, Australia., Mohan GR; Department of Gynaecological Oncology, St John of God Subiaco Hospital, Subiaco, Western Australia, Australia.; Department of Gynaecological Oncology, King Edward Memorial Hospital, Subiaco, Western Australia, Australia., Rodríguez-Antona C; Hereditary Endocrine Cancer Group, Spanish National Cancer Research Center (CNIO), Madrid, Spain.; Centre for Biomedical Network Research on Rare Diseases (CIBERER), Instituto de Salud Carlos III, Madrid, Spain., Ruebner M; Department of Gynecology and Obstetrics, Comprehensive Cancer Center Erlangen-EMN, Friedrich-Alexander University Erlangen-Nuremberg, University Hospital Erlangen, Erlangen, Germany., Ryan A; MRC Clinical Trials Unit, Institute of Clinical Trials & Methodology, University College London, London, UK.; Women's Cancer, Institute for Women's Health, University College London, London, UK., Salfinger SG; Department of Gynaecological Oncology, St John of God Subiaco Hospital, Subiaco, Western Australia, Australia., Sasamoto N; Obstetrics and Gynecology Epidemiology Center, Department of Obstetrics and Gynecology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA., Schildkraut JM; Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, Georgia, USA., Schoemaker MJ; Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK., Shah M; Department of Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge, UK., Sharma R; Tissue Pathology and Diagnostic Oncology, Westmead Hospital, Sydney, New South Wales, Australia., Shvetsov YB; University of Hawaii Cancer Center, Honolulu, Hawaii, USA., Singh N; Department of Pathology, Barts Health National Health Service Trust, London, UK., Sonke GS; Department of Medical Oncology, The Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands., Steele L; Department of Population Sciences, Beckman Research Institute of City of Hope, Duarte, California, USA., Stewart CJR; School for Women's and Infants' Health, University of Western Australia, Perth, Australia., Sundfeldt K; Department of Obstetrics and Gynecology, Inst of Clinical Science, Sahlgrenska Center for Cancer Research, University of Gothenburg, Gothenburg, Sweden., Swerdlow AJ; Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK.; Division of Breast Cancer Research, The Institute of Cancer Research, London, UK., Talhouk A; Department of Obstetrics and Gynecology, University of British Columbia, Vancouver, British Columbia, Canada.; British Columbia's Gynecological Cancer Research Team (OVCARE), University of British Columbia, BC Cancer, and Vancouver General Hospital, Vancouver, British Columbia, Canada., Tan A; Division of Obstetrics and Gynaecology, Faculty of Health and Medical Sciences, University of Western Australia, Crawley, Western Australia, Australia.; Gynaepath WA, Clinipath (Sonic Healthcare), Osbourne Park, Australia., Taylor SE; Division of Gynecologic Oncology, Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA., Terry KL; Obstetrics and Gynecology Epidemiology Center, Department of Obstetrics and Gynecology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA., Tołoczko A; Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland., Traficante N; Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, Victoria, Australia., Van de Vijver KK; Department of Pathology, Ghent University Hospital, Cancer Research Institute Ghent (CRIG), Ghent, Belgium.; Department of Pathology, Antwerp University Hospital, Antwerp, Belgium., van der Aa MA; Department of Research, Netherlands Comprehensive Cancer Organization (IKNL), Utrecht, The Netherlands., Van Gorp T; Division of Gynecologic Oncology, Department of Gynecology and Obstetrics, Leuven Cancer Institute, Leuven, Belgium., Van Nieuwenhuysen E; Division of Gynecologic Oncology, Department of Gynecology and Obstetrics, Leuven Cancer Institute, Leuven, Belgium., van-Wagensveld L; Department of Obstetrics and Gynecology, Maastricht University Medical Centre, Maastricht, The Netherlands.; GROW - School for Oncology and Reproduction, Maastricht University Medical Center, Maastricht, The Netherlands.; Department of Research, Netherlands Comprehensive Cancer Organization (IKNL), Utrecht, The Netherlands., Vergote I; Division of Gynecologic Oncology, Department of Gynecology and Obstetrics, Leuven Cancer Institute, Leuven, Belgium., Vierkant RA; Department of Quantitative Health Sciences, Division of Clinical Trials and Biostatistics, Mayo Clinic, Rochester, Minnesota, USA., Wang C; Department of Quantitative Health Sciences, Division of Computational Biology, Mayo Clinic, Rochester, Minnesota, USA., Wilkens LR; University of Hawaii Cancer Center, Honolulu, Hawaii, USA., Winham SJ; Department of Quantitative Health Sciences, Division of Computational Biology, Mayo Clinic, Rochester, Minnesota, USA., Wu AH; Department of Population Health and Public Health Sciences, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, California, USA., Benitez J; Centre for Biomedical Network Research on Rare Diseases (CIBERER), Instituto de Salud Carlos III, Madrid, Spain.; Human Genetics Group, Spanish National Cancer Research Centre (CNIO), Madrid, Spain., Berchuck A; Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Duke University Medical Center, Durham, North Carolina, USA., Candido Dos Reis FJ; Department of Gynecology and Obstetrics, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil., DeFazio A; The Daffodil Centre, The University of Sydney, A Joint Venture With Cancer Council NSW, Sydney, New South Wales, Australia.; Centre for Cancer Research, The Westmead Institute for Medical Research, University of Sydney, Sydney, New South Wales, Australia.; Department of Gynaecological Oncology, Westmead Hospital, Sydney, New South Wales, Australia.; Discipline of Obstetrics and Gynaecology, The University of Sydney, Sydney, New South Wales, Australia., Fasching PA; Department of Gynecology and Obstetrics, Comprehensive Cancer Center Erlangen-EMN, Friedrich-Alexander University Erlangen-Nuremberg, University Hospital Erlangen, Erlangen, Germany., Goode EL; Department of Quantitative Health Sciences, Division of Epidemiology, Mayo Clinic, Rochester, Minnesota, USA., Goodman MT; Cancer Prevention and Control Program, Cedars-Sinai Cancer, Cedars-Sinai Medical Center, Los Angeles, California, USA., Gronwald J; Department of Genetics and Pathology, International Hereditary Cancer Center, Pomeranian Medical University, Szczecin, Poland., Karlan BY; David Geffen School of Medicine, Department of Obstetrics and Gynecology, University of California at Los Angeles, Los Angeles, California, USA., Kommoss S; Department of Women's Health, Tuebingen University Hospital, Tuebingen, Germany., Menon U; MRC Clinical Trials Unit, Institute of Clinical Trials & Methodology, University College London, London, UK., Sinn HP; Institute of Pathology, Heidelberg University Hospital, Heidelberg, Germany., Staebler A; Institute of Pathology and Neuropathology, Tuebingen University Hospital, Tuebingen, Germany., Brenton JD; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK., Bowtell DD; Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, Victoria, Australia., Pharoah PDP; Department of Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge, UK.; Department of Public Health and Primary Care, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge, UK., Ramus SJ; School of Clinical Medicine, UNSW Medicine and Health, University of NSW Sydney, Sydney, New South Wales, Australia.; Adult Cancer Program, Lowy Cancer Research Centre, University of NSW Sydney, Sydney, New South Wales, Australia., Köbel M; Department of Pathology and Laboratory Medicine, University of Calgary, Foothills Medical Center, Calgary, Alberta, Canada.

Publikováno v: Cancer [Cancer] 2023 Mar 01; Vol. 129 (5), pp. 697-713. Date of Electronic Publication: 2022 Dec 26.

Randomized CLIO/BGOG-ov10 trial of olaparib monotherapy versus physician's choice chemotherapy in relapsed ovarian cancer.

Autor: Vanderstichele A; Belgium and Luxembourg Gynaecological Oncology Group (BGOG), Department of Gynaecology and Obstetrics, University Hospitals Leuven, Leuven, Belgium; Laboratory of Gynaecological Oncology, Leuven Cancer Institute, KU Leuven, Leuven, Belgium., Loverix L; Belgium and Luxembourg Gynaecological Oncology Group (BGOG), Department of Gynaecology and Obstetrics, University Hospitals Leuven, Leuven, Belgium; Laboratory of Gynaecological Oncology, Leuven Cancer Institute, KU Leuven, Leuven, Belgium., Busschaert P; Belgium and Luxembourg Gynaecological Oncology Group (BGOG), Department of Gynaecology and Obstetrics, University Hospitals Leuven, Leuven, Belgium; Laboratory of Gynaecological Oncology, Leuven Cancer Institute, KU Leuven, Leuven, Belgium; Laboratory for Translational Genetics, Department of Oncology, KU Leuven, Leuven, Belgium; Center for Cancer Biology, VIB, Leuven, Belgium., Van Nieuwenhuysen E; Belgium and Luxembourg Gynaecological Oncology Group (BGOG), Department of Gynaecology and Obstetrics, University Hospitals Leuven, Leuven, Belgium; Laboratory of Gynaecological Oncology, Leuven Cancer Institute, KU Leuven, Leuven, Belgium., Han SN; Belgium and Luxembourg Gynaecological Oncology Group (BGOG), Department of Gynaecology and Obstetrics, University Hospitals Leuven, Leuven, Belgium; Laboratory of Gynaecological Oncology, Leuven Cancer Institute, KU Leuven, Leuven, Belgium., Concin N; Belgium and Luxembourg Gynaecological Oncology Group (BGOG), Department of Gynaecology and Obstetrics, University Hospitals Leuven, Leuven, Belgium; Laboratory of Gynaecological Oncology, Leuven Cancer Institute, KU Leuven, Leuven, Belgium., Callewaert T; Belgium and Luxembourg Gynaecological Oncology Group (BGOG), Department of Gynaecology and Obstetrics, University Hospitals Leuven, Leuven, Belgium; Laboratory of Gynaecological Oncology, Leuven Cancer Institute, KU Leuven, Leuven, Belgium., Olbrecht S; Belgium and Luxembourg Gynaecological Oncology Group (BGOG), Department of Gynaecology and Obstetrics, University Hospitals Leuven, Leuven, Belgium; Laboratory of Gynaecological Oncology, Leuven Cancer Institute, KU Leuven, Leuven, Belgium., Salihi R; Belgium and Luxembourg Gynaecological Oncology Group (BGOG), Department of Gynaecology and Obstetrics, University Hospitals Leuven, Leuven, Belgium; Laboratory of Gynaecological Oncology, Leuven Cancer Institute, KU Leuven, Leuven, Belgium., Berteloot P; Belgium and Luxembourg Gynaecological Oncology Group (BGOG), Department of Gynaecology and Obstetrics, University Hospitals Leuven, Leuven, Belgium; Laboratory of Gynaecological Oncology, Leuven Cancer Institute, KU Leuven, Leuven, Belgium., Neven P; Belgium and Luxembourg Gynaecological Oncology Group (BGOG), Department of Gynaecology and Obstetrics, University Hospitals Leuven, Leuven, Belgium; Laboratory of Gynaecological Oncology, Leuven Cancer Institute, KU Leuven, Leuven, Belgium., Lambrechts D; Laboratory for Translational Genetics, Department of Oncology, KU Leuven, Leuven, Belgium; Center for Cancer Biology, VIB, Leuven, Belgium., Van Gorp T; Belgium and Luxembourg Gynaecological Oncology Group (BGOG), Department of Gynaecology and Obstetrics, University Hospitals Leuven, Leuven, Belgium; Laboratory of Gynaecological Oncology, Leuven Cancer Institute, KU Leuven, Leuven, Belgium., Vergote I; Belgium and Luxembourg Gynaecological Oncology Group (BGOG), Department of Gynaecology and Obstetrics, University Hospitals Leuven, Leuven, Belgium; Laboratory of Gynaecological Oncology, Leuven Cancer Institute, KU Leuven, Leuven, Belgium. Electronic address: ignace.vergote@uzleuven.be.

Publikováno v: Gynecologic oncology [Gynecol Oncol] 2022 Apr; Vol. 165 (1), pp. 14-22. Date of Electronic Publication: 2022 Feb 14.

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High-grade serous tubo-ovarian cancer refined with single-cell RNA sequencing: specific cell subtypes influence survival and determine molecular subtype classification.

Autor: Olbrecht S; Department of Obstetrics and Gynaecology, Division of Gynaecological Oncology, University Hospitals Leuven, Leuven, Belgium. siel.olbrecht@uzleuven.be.; Department of Oncology, Laboratory of Gynaecologic Oncology, KU Leuven, Leuven, Belgium. siel.olbrecht@uzleuven.be.; VIB Centre for Cancer Biology, Leuven, Belgium. siel.olbrecht@uzleuven.be., Busschaert P; Department of Oncology, Laboratory of Gynaecologic Oncology, KU Leuven, Leuven, Belgium., Qian J; VIB Centre for Cancer Biology, Leuven, Belgium.; Laboratory for Translational Genetics, Department of Human Genetics, KU Leuven, Leuven, Belgium., Vanderstichele A; Department of Obstetrics and Gynaecology, Division of Gynaecological Oncology, University Hospitals Leuven, Leuven, Belgium.; Department of Oncology, Laboratory of Gynaecologic Oncology, KU Leuven, Leuven, Belgium., Loverix L; Department of Obstetrics and Gynaecology, Division of Gynaecological Oncology, University Hospitals Leuven, Leuven, Belgium.; Department of Oncology, Laboratory of Gynaecologic Oncology, KU Leuven, Leuven, Belgium.; VIB Centre for Cancer Biology, Leuven, Belgium., Van Gorp T; Department of Obstetrics and Gynaecology, Division of Gynaecological Oncology, University Hospitals Leuven, Leuven, Belgium.; Department of Oncology, Laboratory of Gynaecologic Oncology, KU Leuven, Leuven, Belgium., Van Nieuwenhuysen E; Department of Obstetrics and Gynaecology, Division of Gynaecological Oncology, University Hospitals Leuven, Leuven, Belgium.; Department of Oncology, Laboratory of Gynaecologic Oncology, KU Leuven, Leuven, Belgium., Han S; Department of Obstetrics and Gynaecology, Division of Gynaecological Oncology, University Hospitals Leuven, Leuven, Belgium.; Department of Oncology, Laboratory of Gynaecologic Oncology, KU Leuven, Leuven, Belgium., Van den Broeck A; Department of Oncology, Laboratory of Gynaecologic Oncology, KU Leuven, Leuven, Belgium., Coosemans A; Department of Oncology, Laboratory of Tumour Immunology and Immunotherapy, KU Leuven, Leuven, Belgium., Van Rompuy AS; Department of Imaging and Pathology, University Hospitals Leuven, Leuven, Belgium.; Department of Translational Cell and Tissue Research, KU Leuven, Leuven, Belgium., Lambrechts D; VIB Centre for Cancer Biology, Leuven, Belgium. diether.lambrechts@kuleuven.be.; Laboratory for Translational Genetics, Department of Human Genetics, KU Leuven, Leuven, Belgium. diether.lambrechts@kuleuven.be., Vergote I; Department of Obstetrics and Gynaecology, Division of Gynaecological Oncology, University Hospitals Leuven, Leuven, Belgium.; Department of Oncology, Laboratory of Gynaecologic Oncology, KU Leuven, Leuven, Belgium.

Publikováno v: Genome medicine [Genome Med] 2021 Jul 09; Vol. 13 (1), pp. 111. Date of Electronic Publication: 2021 Jul 09.

817P Response to olaparib monotherapy in relapsed ovarian cancer by HRR gene mutational status and HRD scarring analysis: Results from the randomized phase II CLIO trial

Autor: Vanderstichele, A., Loverix, L., De Vogelaere, C., Heyrman, L., Van Gorp, T., Van Nieuwenhuysen, E., Han, S., Olbrecht, S.J.A.R., Berteloot, P., Neven, P., Schepers, R., Busschaert, P., Goossens, D., Lambrechts, D., Vergote, I.B.

Publikováno v: In Annals of Oncology September 2020 31 Supplement 4:S617-S618