Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Loveleena, Bansal"'
Autor:
Loveleena Bansal, Eva-Maria Nichols, Daniel P. Howsmon, Jessica Neisen, Christina M. Bessant, Fraser Cunningham, Sebastien Petit-Frere, Steve Ludbrook, Valeriu Damian
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Motivation: The complement pathway plays a critical role in innate immune defense against infections. Dysregulation between activation and regulation of the complement pathway is widely known to contribute to several diseases. Nevertheless, very few
Externí odkaz:
https://doaj.org/article/af21613b5ce7409b84db7d116ea2d036
Autor:
Erica L. Bradshaw, Mary E. Spilker, Richard Zang, Loveleena Bansal, Handan He, Rhys D.O. Jones, Kha Le, Mark Penney, Edgar Schuck, Brian Topp, Alice Tsai, Christine Xu, Marjoleen J.M.A. Nijsen, Jason R. Chan
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 8, Iss 11, Pp 777-791 (2019)
Abstract Quantitative systems pharmacology (QSP) approaches have been increasingly applied in the pharmaceutical since the landmark white paper published in 2011 by a National Institutes of Health working group brought attention to the discipline. In
Externí odkaz:
https://doaj.org/article/cfab4d71279e43a58805b6626dcdac0c
Autor:
Suruchi Bakshi, Fraser Cunningham, Eva-Maria Nichols, Marta Biedzka-Sarek, Jessica Neisen, Sebastien Petit-Frere, Christina Bessant, Loveleena Bansal, Lambertus A. Peletier, Stefano Zamuner, Piet H. van der Graaf
Publikováno v:
Bull Math Biol
The complement system (CS) is an integral part of innate immunity and can be activated via three different pathways. The alternative pathway (AP) has a central role in the function of the CS. The AP of complement system is implicated in several human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cfcd27cb2ed42f24fe48ff941d978e3
https://doi.org/10.1007/s11538-021-00981-6
https://doi.org/10.1007/s11538-021-00981-6
Autor:
Marjoleen Nijsen, Brian Topp, Edgar Schuck, Richard Zang, Handan He, Loveleena Bansal, Rhys D.O. Jones, Erica L. Bradshaw, Alice Tsai, Mark Penney, Kha Le, Jason R. Chan, Mary E. Spilker, Christine Xu
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 8, Iss 11, Pp 777-791 (2019)
CPT: Pharmacometrics & Systems Pharmacology
CPT: Pharmacometrics & Systems Pharmacology
Quantitative systems pharmacology (QSP) approaches have been increasingly applied in the pharmaceutical since the landmark white paper published in 2011 by a National Institutes of Health working group brought attention to the discipline. In this per
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ef90e38f540b99780bbc2c9356c3236
https://doi.org/10.1002/psp4.12463
https://doi.org/10.1002/psp4.12463
Autor:
Jessica Neisen, Marta Biedzka-Sarek, Sebastien Petit-Frere, Fraser Cunningham, Piet H. van der Graaf, Eva-Maria Nichols, Suruchi Bakshi, Lambertus A. Peletier, Christina Bessant, Loveleena Bansal, Stefano Zamuner
Publikováno v:
Bulletin of Mathematical Biology
The complement system (CS) is an integral part of innate immunity and can be activated via three different pathways. The alternative pathway (AP) has a central role in the function of the CS. The AP of complement system is implicated in several human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91e109822d19b6c2bf2b0fb31bcfb8a5
https://doi.org/10.1007/s11538-020-00708-z
https://doi.org/10.1007/s11538-020-00708-z
Autor:
Erica L. Bradshaw-Pierce, Anjaneya Chimalakonda, Bianca M. Liederer, Loveleena Bansal, Edgar Schuck, Alice Tsai, Fan Wu, Marjoleen Nijsen, Mary E. Spilker, Jason R. Chan, Patricia Schroeder, Jerome T. Mettetal, Kha Le, Akihiro Yamada, Brian Topp, Mark Penney, Christine Xu
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology. 7:135-146
A cross-industry survey was conducted to assess the landscape of preclinical quantitative systems pharmacology (QSP) modeling within pharmaceutical companies. This article presents the survey results, which provide insights on the current state of pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::66d9d94cf63a1d82165b3f3fbd353d6c
https://doi.org/10.1002/psp4.12282
https://doi.org/10.1002/psp4.12282
Autor:
Marjoleen J M A, Nijsen, Fan, Wu, Loveleena, Bansal, Erica, Bradshaw-Pierce, Jason R, Chan, Bianca M, Liederer, Jerome T, Mettetal, Patricia, Schroeder, Edgar, Schuck, Alice, Tsai, Christine, Xu, Anjaneya, Chimalakonda, Kha, Le, Mark, Penney, Brian, Topp, Akihiro, Yamada, Mary E, Spilker
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology
A cross‐industry survey was conducted to assess the landscape of preclinical quantitative systems pharmacology (QSP) modeling within pharmaceutical companies. This article presents the survey results, which provide insights on the current state of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6c65d59eb77aafe031fc68437a72541c
https://pubmed.ncbi.nlm.nih.gov/29349875
https://pubmed.ncbi.nlm.nih.gov/29349875
Publikováno v:
AIChE Journal. 60:181-192
It is common that only a subset of the parameters of models can be accurately estimated. One approach for identifying a subset of parameters for estimation is to perform clustering of the parameters into groups based upon their sensitivity vectors. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5fa84a683f94d1e808a0175a2b7ba0cb
https://doi.org/10.1002/aic.14265
https://doi.org/10.1002/aic.14265
Publikováno v:
Chemical Engineering Science. 101:191-198
Fluorescent proteins have found widespread applications for analysis of biological systems as they can be used to track various events within living cells. Multiple fluorescent proteins are also simultaneously used to monitor different aspects of bio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::54f51442aa9820c83f301b3ddc3524b0
https://doi.org/10.1016/j.ces.2013.06.021
https://doi.org/10.1016/j.ces.2013.06.021
Publikováno v:
AIChE Journal. 58:3751-3762
Signal transduction pathways are characterized by complex biochemical reactions which involve a large number of proteins. The availability and quality of experimental data pose challenges for identifying the role of individual proteins in these pathw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::497188680cf09b18d7a3d792327163d6
https://doi.org/10.1002/aic.13782
https://doi.org/10.1002/aic.13782