Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Lovejot M. Singh"'
Autor:
Brian T. Fife, Matthew F. Mescher, Christopher G. Tucker, Jason S. Mitchell, Lovejot M. Singh, Joseph C. Wilson, Alexander J. Dwyer, Lalit K. Beura, Brandon J. Burbach, Tijana Martinov
Publikováno v:
J Immunol
Optimal ex vivo expansion protocols of tumor-specific T cells followed by adoptive cell therapy must yield T cells able to home to tumors and effectively kill them. Our previous study demonstrated ex vivo activation in the presence of IL-12–induced
Autor:
Kristin A. Hogquist, Elise R. Breed, Brian T. Fife, Christopher G. Tucker, Linnea A. Swanson, Jenna K. Johnson, Jason S. Mitchell, Joseph C. Wilson, Alexander J. Dwyer, Nathanael L. Sahli, Justin A. Spanier, Tijana Martinov, Lovejot M. Singh
Publikováno v:
J Immunol
Programmed death-1 (PD-1) inhibits T and B cell function upon ligand binding. PD-1 blockade revolutionized cancer treatment, and although numerous patients respond, some develop autoimmune-like symptoms or overt autoimmunity characterized by autoanti