Pyridopyrimidinones as a new chemotype of calcium dependent protein kinase 1 (CDPK1) inhibitors for Cryptosporidium

Autor: Waldron-Young, Elise, Wijitrmektong, Wissarut, Choi, Ryan, Whitman, Grant R., Hulverson, Matthew A., Charania, Raheela, Keelaghan, Aidan, Li, Li, Srinual, Songpol, Nikhar, Sameer, McNamara, Case W., Love, Melissa S., Huerta, Lauren, Bakowski, Malina A., Hu, Ming, Van Voorhis, Wesley C., Mead, Jan R., Cuny, Gregory D.

Publikováno v: In Molecular & Biochemical Parasitology December 2024 260

'On Earth as It Is in Heaven?' The Creation of the Bastides of Southwest France

Autor: Love, Melissa Jordan

In southwest France starting in the early thirteenth century, an estimated 500 to 700 new towns were created over the course of about 150 years. These new towns, or "bastides," were most often created on unoccupied lands and took the form of a geomet

Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis

Autor: Baragan˜a, Beatriz, Forte, Barbara, Choi, Ryan, Hewitt, Stephen Nakazawa, Bueren-Calabuig, Juan A., Pisco, Joa˜o Pedro, Peet, Caroline, Dranow, David M., Robinson, David A., Jansen, Chimed, Norcross, Neil R., Vinayak, Sumiti, Anderson, Mark, Brooks, Carrie F., Cooper, Caitlin A., Damerow, Sebastian, Delves, Michael, Dowers, Karen, Duffy, James, Edwards, Thomas E., Hallyburton, Irene, Horst, Benjamin G., Hulverson, Matthew A., Ferguson, Liam, Jiménez-Díaz, María Belén, Jumani, Rajiv S., Lorimer, Donald D., Love, Melissa S., Maher, Steven, Matthews, Holly, McNamara, Case W., Miller, Peter, O’Neill, Sandra, Ojo, Kayode K., Osuna-Cabello, Maria, Pinto, Erika, Post, John, Riley, Jennifer, Rottmann, Matthias, Sanz, Laura M., Scullion, Paul, Sharma, Arvind, Shepherd, Sharon M., Shishikura, Yoko, Simeons, Frederick R. C., Stebbins, Erin E., Stojanovski, Laste, Straschil, Ursula, Tamaki, Fabio K., Tamjar, Jevgenia, Torrie, Leah S., Vantaux, Amélie, Witkowski, Benoît, Wittlin, Sergio, Yogavel, Manickam, Zuccotto, Fabio, Angulo-Barturen, Iñigo, Sinden, Robert, Baum, Jake, Gamo, Francisco-Javier, Mäser, Pascal, Kyle, Dennis E., Winzeler, Elizabeth A., Myler, Peter J., Wyatt, Paul G., Floyd, David, Matthews, David, Sharma, Amit, Striepen, Boris, Huston, Christopher D., Gray, David W., Fairlamb, Alan H., Pisliakov, Andrei V., Walpole, Chris, Read, Kevin D., Van Voorhis, Wesley C., Gilbert, Ian H.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America, 2019 Apr 01. 116(14), 7015-7020.

Externí odkaz: https://www.jstor.org/stable/26698606

The ReFRAME library as a comprehensive drug repurposing library and its application to the treatment of cryptosporidiosis

Autor: Janes, Jeff, Young, Megan E., Chen, Emily, Rogers, Nicole H., Burgstaller-Muehlbacher, Sebastian, Hughes, Laura D., Love, Melissa S., Hull, Mitchell V., Kuhen, Kelli L., Woods, Ashley K., Joseph, Sean B., Petrassi, H. Michael, McNamara, Case W., Tremblay, Matthew S., Su, Andrew I., Schultz, Peter G., Chatterjee, Arnab K.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America, 2018 Oct . 115(42), 10750-10755.

Externí odkaz: https://www.jstor.org/stable/26532283

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