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Surface protein and functional analyses identify CD4⁺CD39⁺ TCR αβ⁺ and activated TCR Vδ1⁺ cells with distinct pro-inflammatory functions in Crohn's disease lesions.

Autor: Devan, Jan, Nosi, Vladimir, Spagnuolo, Julian, Chancellor, Andrew, Beshirova, Aisha, Loureiro, Jose Pedro, Vacchini, Alessandro, Hendrik Niess, Jan, Calogero, Raffaele, Mori, Lucia, De Libero, Gennaro, Hruz, Petr

Publikováno v: Clinical & Experimental Immunology; Jan2024, Vol. 215 Issue 1, p79-93, 15p

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Surface protein and functional analyses identify CD4+CD39+ TCR αβ+ and activated TCR Vδ1+ cells with distinct pro-inflammatory functions in Crohn's disease lesions.

Autor: Devan J; Experimental Immunology, Department of Biomedicine, University Hospital Basel, University of Basel, Basel, Switzerland., Nosi V; Experimental Immunology, Department of Biomedicine, University Hospital Basel, University of Basel, Basel, Switzerland.; Department of Molecular Biotechnology and Health Sciences, University of Torino, Torino, Italy., Spagnuolo J; Experimental Immunology, Department of Biomedicine, University Hospital Basel, University of Basel, Basel, Switzerland., Chancellor A; Experimental Immunology, Department of Biomedicine, University Hospital Basel, University of Basel, Basel, Switzerland., Beshirova A; Experimental Immunology, Department of Biomedicine, University Hospital Basel, University of Basel, Basel, Switzerland., Loureiro JP; Experimental Immunology, Department of Biomedicine, University Hospital Basel, University of Basel, Basel, Switzerland., Vacchini A; Experimental Immunology, Department of Biomedicine, University Hospital Basel, University of Basel, Basel, Switzerland., Hendrik Niess J; Gastroenterology, Department of Biomedicine, University of Basel, Clarunis, Basel, Switzerland.; Department of Clinical Research, University of Basel, Basel, Switzerland.; University Center for Gastrointestinal and Liver Diseases, Basel, Switzerland., Calogero R; Department of Molecular Biotechnology and Health Sciences, University of Torino, Torino, Italy., Mori L; Experimental Immunology, Department of Biomedicine, University Hospital Basel, University of Basel, Basel, Switzerland., De Libero G; Experimental Immunology, Department of Biomedicine, University Hospital Basel, University of Basel, Basel, Switzerland., Hruz P; Experimental Immunology, Department of Biomedicine, University Hospital Basel, University of Basel, Basel, Switzerland.; University Center for Gastrointestinal and Liver Diseases, Basel, Switzerland.

Publikováno v: Clinical and experimental immunology [Clin Exp Immunol] 2024 Jan 09; Vol. 215 (1), pp. 79-93.