Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Lourdes Rios"'
Publikováno v:
Pharmaceutics, Vol 16, Iss 9, p 1140 (2024)
Bacterial infections and antimicrobial resistance are posing substantial difficulties to the worldwide healthcare system. The constraints of conventional diagnostic and therapeutic approaches in dealing with continuously changing infections highlight
Externí odkaz:
https://doaj.org/article/85d13ded0b4043b09b1a077e77e37d9c
Autor:
Gustavo A Orozco, Kalle Karjalainen, Eng Kuan Moo, Lauri Stenroth, Petri Tanska, Jaqueline Lourdes Rios, Teemu V Tuomainen, Mikko J Nissi, Hanna Isaksson, Walter Herzog, Rami K Korhonen
Publikováno v:
PLoS Computational Biology, Vol 18, Iss 6, p e1009398 (2022)
Abnormal loading of the knee due to injuries or obesity is thought to contribute to the development of osteoarthritis (OA). Small animal models have been used for studying OA progression mechanisms. However, numerical models to study cartilage respon
Externí odkaz:
https://doaj.org/article/13d4218103bd42c6a50bb01165b0ccd4
Autor:
Jaqueline Lourdes Rios, Kevin Rudi Boldt, James William Mather, Ruth Anne Seerattan, David Arthur Hart, Walter Herzog
Publikováno v:
Sports Medicine - Open, Vol 4, Iss 1, Pp 1-10 (2018)
Abstract Background Walking and running provide cyclical loading to the knee which is thought essential for joint health within a physiological window. However, exercising outside the physiological window, e.g. excessive cyclical loading, may produce
Externí odkaz:
https://doaj.org/article/f3a2d31d4a5840b3b6e66744d75d3179
Autor:
Jaqueline Lourdes Rios
Background: Mesenchymal stromal/stem cells (MSCs) and MSC-derived extracellular vesicles (MSC-EVs) hold promise as a disease modifying treatment in Osteoarthritis (OA). Obesity, and its associated inflammation, contribute to OA development and metabo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d311cc8fc28ffe7248d4093cb6e68689
https://doi.org/10.21203/rs.3.rs-2096990/v1
https://doi.org/10.21203/rs.3.rs-2096990/v1
Autor:
Raylene A. Reimer, Jennifer Joanne O'Reilly, Walter Herzog, Jaqueline Lourdes Rios, Graham Z. MacDonald, Curtis Ostertag, Teja Klancic, Kelsey H. Collins, Ian C. Smith
Publikováno v:
Applied Physiology, Nutrition, and Metabolism. 46:1389-1399
Obesity is a worldwide health concern associated with impaired physical function. It is not clear if contractile protein dysfunction contributes to the impairment of muscle function observed with obesity. The purpose of this study was to examine if d
Autor:
Jaqueline Lourdes Rios, Dora Sapède, Farida Djouad, Anna E. Rapp, Annemarie Lang, Jonathan Larkin, Christoph Ladel, Ali Mobasheri
Publikováno v:
Current Protocols. 2
Osteoarthritis (OA) is the most common form of arthritis and a major source of pain and disability in the adult population. There is a significant unmet medical need for the development of effective pharmacological therapies for the treatment of OA.
Autor:
Gustavo A. Orozco, Kalle Karjalainen, Eng Kuan Moo, Lauri Stenroth, Petri Tanska, Jaqueline Lourdes Rios, Teemu V. Tuomainen, Mikko J. Nissi, Hanna Isaksson, Walter Herzog, Rami K. Korhonen
Publikováno v:
PLOS Computational Biology. 19:e1011025
Autor:
Kalle Karjalainen, Rami K. Korhonen, Petri Tanska, Teemu V. Tuomainen, Mikko J. Nissi, Eng Kuan Moo, Jaqueline Lourdes Rios, Lauri Stenroth, Gustavo A. Orozco, Walter Herzog, Hanna Isaksson
Publikováno v:
Orozco, G A, Karjalainen, K, Moo, E K, Stenroth, L, Tanska, P, Rios, J L, Tuomainen, T V, Nissi, M J, Isaksson, H, Herzog, W & Korhonen, R K 2022, ' A musculoskeletal finite element model of rat knee joint for evaluating cartilage biomechanics during gait ', PLOS Computational Biology, vol. 18, no. 6, e1009398, pp. 1-23 . https://doi.org/10.1371/journal.pcbi.1009398
Abnormal loading of the knee due to injuries or obesity is thought to contribute to the development of osteoarthritis (OA). Small animal models have been used for studying OA progression mechanisms. However, numerical models to study cartilage respon
Autor:
Loretta Ko, Jaqueline Lourdes Rios, Walter Herzog, Venus Joumaa, Andrew Sawatsky, Shuyue Liu, Fernando Diefenthaeler, Raylene A. Reimer, David A. Hart
Publikováno v:
Journal of Biomechanics. 88:148-154
The worldwide trajectory of increasing obesity rates is a major health problem precipitating a rise in the prevalence of a variety of co-morbidities and chronic diseases. Tendinopathy, in weight and non-weight bearing tendons, in individuals with ove
Autor:
H. de Brito Fontana, J. Lourdes Rios, R. A. Seerattan, V. Joumaa, D. A. Hart, R. A. Reimer, W. Herzog
Publikováno v:
Annals of the Rheumatic Diseases. 81:1157.1-1158
BackgroundA high-fat/high-sucrose (HFS) diet leads to osteoarthritis-like damage in the knee and shoulder (Collins et al., 2018), and to a low-level systemic inflammation that is accompanied by a decrease in insulin sensitivity. Recently, we demonstr