Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Lourdes Massieu"'
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 16 (2023)
A growing body of evidence supports the beneficial effects of the ketone bodies (KBs), acetoacetate and β-hydroxybutyrate (BHB), on diverse physiological processes and diseases. Hence, KBs have been suggested as therapeutic tools for neurodegenerati
Externí odkaz:
https://doaj.org/article/4269d00406524007b381ead1a1b581f6
Publikováno v:
Cell Death Discovery, Vol 7, Iss 1, Pp 1-15 (2021)
Abstract Altered protein homeostasis is associated with neurodegenerative diseases and acute brain injury induced under energy depletion conditions such as ischemia. The accumulation of damaged or unfolded proteins triggers the unfolded protein respo
Externí odkaz:
https://doaj.org/article/8a3babecd5f44278a0a5b429c3d9b480
Autor:
Juan Carlos Gómora-García, Teresa Montiel, Melanie Hüttenrauch, Ashley Salcido-Gómez, Lizbeth García-Velázquez, Yazmin Ramiro-Cortés, Juan Carlos Gomora, Susana Castro-Obregón, Lourdes Massieu
Publikováno v:
Cells, Vol 12, Iss 3, p 486 (2023)
Mitochondrial activity and quality control are essential for neuronal homeostasis as neurons rely on glucose oxidative metabolism. The ketone body, D-β-hydroxybutyrate (D-BHB), is metabolized to acetyl-CoA in brain mitochondria and used as an energy
Externí odkaz:
https://doaj.org/article/5119d52593034d85a04f9f118226e29b
Autor:
Feliciano Monterrubio-Ledezma, Fernando Navarro-García, Lourdes Massieu, Ricardo Mondragón-Flores, Luz Adriana Soto-Ponce, Jonathan J. Magaña, Bulmaro Cisneros
Publikováno v:
Cells, Vol 12, Iss 2, p 275 (2023)
Hutchinson-Gilford progeria syndrome (HGPS) is a rare premature aging disorder caused by the expression of progerin, a mutant variant of Lamin A. Recently, HGPS studies have gained relevance because unraveling its underlying mechanism would help to u
Externí odkaz:
https://doaj.org/article/522ab2153bd04ec2928cf2b54562f744
Autor:
Sandra Lizbeth Morales-Rosales, Roberto Santín-Márquez, Pedro Posadas-Rodriguez, Ruth Rincon-Heredia, Teresa Montiel, Raúl Librado-Osorio, Armando Luna-López, Nadia Alejandra Rivero-Segura, Claudio Torres, Agustina Cano-Martínez, Alejandro Silva-Palacios, Paulina Cortés-Hernández, Julio Morán, Lourdes Massieu, Mina Konigsberg
Publikováno v:
Frontiers in Aging Neuroscience, Vol 13 (2021)
The decline in brain function during aging is one of the most critical health problems nowadays. Although senescent astrocytes have been found in old-age brains and neurodegenerative diseases, their impact on the function of other cerebral cell types
Externí odkaz:
https://doaj.org/article/1967aad2ba50444993be67ee6f81dcf4
Publikováno v:
Journal of Neuroinflammation, Vol 16, Iss 1, Pp 1-19 (2019)
Abstract Background During excitotoxic damage, neuronal death results from the increase in intracellular calcium, the induction of oxidative stress, and a subsequent inflammatory response. NADPH oxidases (NOX) are relevant sources of reactive oxygen
Externí odkaz:
https://doaj.org/article/abce363b4b9748299476327aa2179659
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 14 (2020)
Glucose supply from blood is mandatory for brain functioning and its interruption during acute hypoglycemia or cerebral ischemia leads to brain injury. Alternative substrates to glucose such as the ketone bodies (KB), acetoacetate (AcAc), and β-hydr
Externí odkaz:
https://doaj.org/article/6ad918e773514a4d8314ce97df60373a
Autor:
Erika A. Peláez Coyotl, Jacqueline Barrios Palacios, Gabriel Muciño, Daniel Moreno-Blas, Miguel Costas, Teresa Montiel Montes, Christian Diener, Salvador Uribe-Carvajal, Lourdes Massieu, Susana Castro-Obregón, Octavio Ramos Espinosa, Dulce Mata Espinosa, Jorge Barrios-Payan, Juan Carlos León Contreras, Gerardo Corzo, Rogelio Hernández-Pando, Gabriel Del Rio
Publikováno v:
Pharmaceutics, Vol 12, Iss 11, p 1071 (2020)
Mycobacterium tuberculosis (MTB) is the principal cause of human tuberculosis (TB), which is a serious health problem worldwide. The development of innovative therapeutic modalities to treat TB is mainly due to the emergence of multi drug resistant (
Externí odkaz:
https://doaj.org/article/301557ccf09347ec99a2a4e8bd2463b4
Autor:
Nadia A Rivero-Segura, Edgar Flores-Soto, Selene García de la Cadena, Isabel Coronado-Mares, Juan C Gomez-Verjan, Diana G Ferreira, Erika Alejandra Cabrera-Reyes, Luísa V Lopes, Lourdes Massieu, Marco Cerbón
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0176910 (2017)
Prolactin (PRL) is a peptidic hormone that displays pleiotropic functions in the organism including different actions in the brain. PRL exerts a neuroprotective effect against excitotoxicity produced by glutamate (Glu) or kainic acid in both in vitro
Externí odkaz:
https://doaj.org/article/7a7bb504fde74947a6245be0c1e45d1d
Publikováno v:
Neurobiology of Disease, Vol 34, Iss 1, Pp 78-86 (2009)
Glutamate excitotoxicity has been implicated in the neuropathology of Huntington's disease (HD), due to the toxicity of glutamate receptor agonists on striatal medium spiny neurons (MSN), the most affected neuronal population in HD. Previous studies
Externí odkaz:
https://doaj.org/article/dd0d6c896719495a886f55598188a072