An updated evolutionary study of Flaviviridae NS3 helicase and NS5 RNA-dependent RNA polymerase reveals novel invariable motifs as potential pharmacological targets

Autor: Papageorgiou, L. Loukatou, S. Sofia, K. Maroulis, D. Vlachakis, D.

The rate of Flaviviridae family virus infections worldwide has increased dramatically in the last few years. In addition, infections caused by arthropod vector viruses including Hepatitis C, West Nile, Dengue fever, Yellow fever and Japanese encephal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2127::14410f77db2eefe41a8032ffa7ea244e
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3086102

Fitness adaptations of Japanese encephalitis virus in pigs following vector-free serial passaging.

Autor: Marti, Andrea^1,2,3 (AUTHOR), Nater, Alexander⁴ (AUTHOR), Pego Magalhaes, Jenny^1,2 (AUTHOR), Almeida, Lea^1,2 (AUTHOR), Lewandowska, Marta^1,2,3 (AUTHOR), Liniger, Matthias^1,2 (AUTHOR), Ruggli, Nicolas^1,2 (AUTHOR), Grau-Roma, Llorenç^2,5 (AUTHOR), Brito, Francisco^1,2 (AUTHOR), Alnaji, Fadi G.⁶ (AUTHOR), Vignuzzi, Marco^6,7 (AUTHOR), García-Nicolás, Obdulio^1,2 (AUTHOR), Summerfield, Artur^1,2 (AUTHOR) artur.summerfield@unibe.ch

Publikováno v: PLoS Pathogens. 8/26/2024, Vol. 20 Issue 8, p1-30. 30p.

An updated evolutionary study of Flaviviridae NS3 helicase and NS5 RNA-dependent RNA polymerase reveals novel invariable motifs as potential pharmacological targets.

Autor: Papageorgiou L; Computational Biology & Medicine Group, Biomedical Research Foundation, Academy of Athens, Soranou Efessiou 4, Athens 11527, Greece. dvlachakis@bioacademy.gr and Department of Informatics and Telecommunications, National and Kapodistrian University of Athens, University Campus, Athens, 15784, Greece., Loukatou S; Computational Biology & Medicine Group, Biomedical Research Foundation, Academy of Athens, Soranou Efessiou 4, Athens 11527, Greece. dvlachakis@bioacademy.gr., Sofia K; IMGT®, The International ImMunoGeneTics Information System®, Universite de Montpellier, Laboratoire d'ImmunoGenetique Moleculaire LIGM, UPR CNRS 1142, Institut de Genetique Humaine, 141 rue de la Cardonille, Montpellier, 34396 Cedex 5, France., Maroulis D; Department of Informatics and Telecommunications, National and Kapodistrian University of Athens, University Campus, Athens, 15784, Greece., Vlachakis D; Computational Biology & Medicine Group, Biomedical Research Foundation, Academy of Athens, Soranou Efessiou 4, Athens 11527, Greece. dvlachakis@bioacademy.gr.

Publikováno v: Molecular bioSystems [Mol Biosyst] 2016 Jun 21; Vol. 12 (7), pp. 2080-93.

Molecular dynamics simulations through GPU video games technologies.

Autor: Loukatou S; Computational Biology & Medicine Group, Biomedical Research Foundation, Academy of Athens, Soranou Efessiou 4, Athens 11527, Greece., Papageorgiou L; Computational Biology & Medicine Group, Biomedical Research Foundation, Academy of Athens, Soranou Efessiou 4, Athens 11527, Greece; Department of Informatics and Telecommunications, National and Kapodistrian University of Athens, University Campus, Athens 15784, Greece., Fakourelis P; Computational Biology & Medicine Group, Biomedical Research Foundation, Academy of Athens, Soranou Efessiou 4, Athens 11527, Greece; Department of Computer Engineering and Informatics Faculty, University of Patras, Patras 26500, Greece., Filntisi A; Computational Biology & Medicine Group, Biomedical Research Foundation, Academy of Athens, Soranou Efessiou 4, Athens 11527, Greece; School of Electrical and Computer Engineering, National Technical University of Athens, Athens, Greece., Polychronidou E; Computational Biology & Medicine Group, Biomedical Research Foundation, Academy of Athens, Soranou Efessiou 4, Athens 11527, Greece; Department of Informatics, Ionian University, Tsirigoti Square 7, Corfu 49100, Greece., Bassis I; Computational Biology & Medicine Group, Biomedical Research Foundation, Academy of Athens, Soranou Efessiou 4, Athens 11527, Greece., Megalooikonomou V; Department of Computer Engineering and Informatics Faculty, University of Patras, Patras 26500, Greece., Makałowski W; Institute of Bioinformatics, University of Münster, Niels-Stensen-Straße 14, Münster 48149, Germany., Vlachakis D; Computational Biology & Medicine Group, Biomedical Research Foundation, Academy of Athens, Soranou Efessiou 4, Athens 11527, Greece; Department of Computer Engineering and Informatics Faculty, University of Patras, Patras 26500, Greece; Bionetwork ltd. 15234, Chalandri, Athens, Greece., Kossida S; Computational Biology & Medicine Group, Biomedical Research Foundation, Academy of Athens, Soranou Efessiou 4, Athens 11527, Greece.

Publikováno v: Journal of molecular biochemistry [J Mol Biochem] 2014; Vol. 3 (2), pp. 64-71. Date of Electronic Publication: 2014 Jun 30.

ADRA2B and HTR1A: An Updated Study of the Biogenic Amine Receptors Reveals Novel Conserved Motifs Which Play Key Role in Mental Disorders.

Autor: Papageorgiou L; Laboratory of Genetics, Department of Biotechnology, School of Applied Biology and Biotechnology, Agricultural University of Athens, Athens, Greece., Christou E; Laboratory of Genetics, Department of Biotechnology, School of Applied Biology and Biotechnology, Agricultural University of Athens, Athens, Greece., Louka E; Laboratory of Genetics, Department of Biotechnology, School of Applied Biology and Biotechnology, Agricultural University of Athens, Athens, Greece., Papakonstantinou E; Laboratory of Genetics, Department of Biotechnology, School of Applied Biology and Biotechnology, Agricultural University of Athens, Athens, Greece., Diakou I; Laboratory of Genetics, Department of Biotechnology, School of Applied Biology and Biotechnology, Agricultural University of Athens, Athens, Greece., Pierouli K; Laboratory of Genetics, Department of Biotechnology, School of Applied Biology and Biotechnology, Agricultural University of Athens, Athens, Greece., Dragoumani K; Laboratory of Genetics, Department of Biotechnology, School of Applied Biology and Biotechnology, Agricultural University of Athens, Athens, Greece., Bacopoulou F; University Research Institute of Maternal and Child Health & Precision Medicine, National and Kapodistrian University of Athens, 'Aghia Sophia' Children's Hospital, Athens, Greece., Chrousos GP; University Research Institute of Maternal and Child Health & Precision Medicine, National and Kapodistrian University of Athens, 'Aghia Sophia' Children's Hospital, Athens, Greece., Eliopoulos E; Laboratory of Genetics, Department of Biotechnology, School of Applied Biology and Biotechnology, Agricultural University of Athens, Athens, Greece., Vlachakis D; Laboratory of Genetics, Department of Biotechnology, School of Applied Biology and Biotechnology, Agricultural University of Athens, Athens, Greece. dimvl@aua.gr.; University Research Institute of Maternal and Child Health & Precision Medicine, National and Kapodistrian University of Athens, 'Aghia Sophia' Children's Hospital, Athens, Greece. dimvl@aua.gr.; Division of Endocrinology and Metabolism, Center of Clinical, Experimental Surgery and Translational Research, Biomedical Research Foundation of the Academy of Athens, Athens, Greece. dimvl@aua.gr.

Publikováno v: Advances in experimental medicine and biology [Adv Exp Med Biol] 2023; Vol. 1423, pp. 79-99.