Výsledky vyhledávání - "Louk V. A. M. Beex"

The complex between urokinase-type plasminogen activator (uPA) and its type-1 inhibitor (PAI-I) independently predicts response to first-line endocrine therapy in advanced breast cancer

Autor: Peggy, Manders, Vivianne C G, Tjan-Heijnen, Paul N, Span, Nicolai, Grebenchtchikov, Anneke J, Geurts-Moespot, Doorléne T H, van Tienoven, Louk V A M, Beex, Fred C G J, Sweep

Publikováno v: Thrombosis and haemostasis. 91(3)

It has been shown that urokinase-type plasminogen activator (uPA) and its main inhibitor (PAI-I) have predictive value for therapy success in advanced breast cancer. Levels of the complex between uPA and PAI-I, formed when both molecules are in their

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::bc504d9bed11683e8eedb6543945a759
https://pubmed.ncbi.nlm.nih.gov/14983227

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Predictive impact of urokinase-type plasminogen activator: plasminogen activator inhibitor type-1 complex on the efficacy of adjuvant systemic therapy in primary breast cancer

Autor: Peggy, Manders, Vivianne C G, Tjan-Heijnen, Paul N, Span, Nicolai, Grebenchtchikov, John A, Foekens, Louk V A M, Beex, C G J Fred, Sweep

Publikováno v: Cancer research. 64(2)

One of the most thoroughly studied systems in relation to its prognostic relevance in patients with breast cancer, is the plasminogen activation system. This system comprises of, among others, the urokinase-type plasminogen activator (uPA) and its ma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::748dfe850d70c8258b6649c9922d3076
https://pubmed.ncbi.nlm.nih.gov/14744782

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Vascular endothelial growth factor independently predicts the efficacy of postoperative radiotherapy in node-negative breast cancer patients

Autor: Peggy, Manders, Fred C G J, Sweep, Vivianne C G, Tjan-Heijnen, Anneke, Geurts-Moespot, Doorléne T H, van Tienoven, John A, Foekens, Paul N, Span, Jan, Bussink, Louk V A M, Beex

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research. 9(17)

Vascular endothelial growth factor (VEGF) is a mediator of angiogenesis and is up-regulated under hypoxic conditions. Hypoxic tumors are known to exhibit resistance to radiotherapy. We investigated the association between VEGF levels in tumor tissue

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f14daf0f611f6547f216050198418bac
https://pubmed.ncbi.nlm.nih.gov/14695136

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5-FU-induced peripheral neuropathy: a rare complication of a well-known drug

Autor: Hanneke W M, van Laarhoven, Carla C P, Verstappen, Louk V A M, Beex, Arnoud C, Kappelle, Cornelis J A, Punt

Publikováno v: Anticancer research. 23(1B)

Peripheral neuropathy is a rare complication of the commonly used cytotoxic drug 5-fluorouracil (5-FU). We report a case of 5-FU-induced peripheral neuropathy in a patient with metastatic colorectal carcinoma. Discontinuation of 5-FU therapy is recom

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::484fbaeff83b977ae137316fdd4046d3
https://pubmed.ncbi.nlm.nih.gov/12680161

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Matrix metalloproteinase inhibitor reversion-inducing cysteine-rich protein with Kazal motifs: a prognostic marker for good clinical outcome in human breast carcinoma

Autor: C.G.J. Sweep, Raija L. P. Lindberg, Louk V. A. M. Beex, Peggy Manders, David Leppert, Paul N. Span

Publikováno v: Cancer, 97, 11, pp. 2710-5
Cancer, 97, 2710-5

Item does not contain fulltext BACKGROUND: The recently described reversion-inducing cysteine-rich protein with Kazal motifs (RECK) inhibits membrane Type 1 matrix metalloproteinase (MMP-14), MMP-2, and MMP-9 secretion and enzymatic activity. Its exp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e5ad31cea6d6c54467211316a6262a8
https://hdl.handle.net/2066/143698