Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Loujin Song"'
Autor:
Stephen E Flaherty III, Olivier Bezy, Brianna LaCarubba Paulhus, LouJin Song, Mary Piper, Jincheng Pang, Yoson Park, Shoh Asano, Yu-Chin Lien, John D Griffin, Andrew Robertson, Alan Opsahl, Dinesh Hirenallur Shanthappa, Youngwook Ahn, Evanthia Pashos, Rebecca A Simmons, Morris J Birnbaum, Zhidan Wu
Publikováno v:
eLife, Vol 12 (2024)
From a forward mutagenetic screen to discover mutations associated with obesity, we identified mutations in the Spag7 gene linked to metabolic dysfunction in mice. Here, we show that SPAG7 KO mice are born smaller and develop obesity and glucose into
Externí odkaz:
https://doaj.org/article/4c48137f953943ab9ab7d2ee4fda5031
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 11 (2024)
The lymphatic vascular system spans nearly every organ in the body and serves as an important network that maintains fluid, metabolite, and immune cell homeostasis. Recently, there has been a growing interest in the role of lymphatic biology in chron
Externí odkaz:
https://doaj.org/article/fb9ea4c13e854ae6b023876d4a91122a
Autor:
Rachel J. Roth Flach, Eliza Bollinger, Allan R. Reyes, Brigitte Laforest, Bethany L. Kormos, Shenping Liu, Matthew R. Reese, Luis A. Martinez Alsina, Leanne Buzon, Yuan Zhang, Bruce Bechle, Amy Rosado, Parag V. Sahasrabudhe, John Knafels, Samit K. Bhattacharya, Kiyoyuki Omoto, John C. Stansfield, Liam D. Hurley, LouJin Song, Lina Luo, Susanne B. Breitkopf, Mara Monetti, Teresa Cunio, Brendan Tierney, Frank J. Geoly, Jake Delmore, C. Parker Siddall, Liang Xue, Ka N. Yip, Amit S. Kalgutkar, Russell A. Miller, Bei B. Zhang, Kevin J. Filipski
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Branched chain amino acid (BCAA) catabolic impairments have been implicated in several diseases. Branched chain ketoacid dehydrogenase (BCKDH) controls the rate limiting step in BCAA degradation, the activity of which is inhibited by BCKDH k
Externí odkaz:
https://doaj.org/article/f9d9823491ce46a3808353f3a122b4ab
Autor:
Flaherty III, Stephen E., Bezy, Olivier, Paulhus, Brianna LaCarubba, LouJin Song, Piper, Mary, Jincheng Pang, Yoson Park, Asano, Shoh, Yu-Chin Lien, Griffin, John D., Robertson, Andrew, Opsahl, Alan, Shanthappa, Dinesh Hirenallur, Youngwook Ahn, Pashos, Evanthia, Simmons, Rebecca A., Birnbaum, Morris J., Zhidan Wu
Publikováno v:
eLife; 7/26/2024, p1-23, 23p
Autor:
Ja Young Kim-Muller, LouJin Song, Brianna LaCarubba Paulhus, Evanthia Pashos, Xiangping Li, Anthony Rinaldi, Stephanie Joaquim, John C. Stansfield, Jiangwei Zhang, Andrew Robertson, Jincheng Pang, Alan Opsahl, Magalie Boucher, Danna Breen, Katherine Hales, Abdul Sheikh, Zhidan Wu, Bei B. Zhang
Publikováno v:
Cell Reports, Vol 42, Iss 1, Pp 111947- (2023)
Summary: Cancer cachexia is a disorder characterized by involuntary weight loss and impaired physical performance. Decline in physical performance of patients with cachexia is associated with poor quality of life, and currently there are no effective
Externí odkaz:
https://doaj.org/article/7269fc75244043ad853bd7fb8484fed2
Publikováno v:
Frontiers in Cardiovascular Medicine; 2024, p1-15, 15p
Autor:
LouJin Song, Xian Chen, Terri A Swanson, Brianna LaViolette, Jincheng Pang, Teresa Cunio, Michael W Nagle, Shoh Asano, Katherine Hales, Arun Shipstone, Hanna Sobon, Sabra D Al-Harthy, Youngwook Ahn, Steven Kreuser, Andrew Robertson, Casey Ritenour, Frank Voigt, Magalie Boucher, Furong Sun, William C Sessa, Rachel J Roth Flach
Publikováno v:
eLife, Vol 9 (2020)
The lymphatic vasculature is involved in the pathogenesis of acute cardiac injuries, but little is known about its role in chronic cardiac dysfunction. Here, we demonstrate that angiotensin II infusion induced cardiac inflammation and fibrosis at 1 w
Externí odkaz:
https://doaj.org/article/cffe82a9df6a402a999f6d3b68cbed94
Publikováno v:
Stem Cell Reports, Vol 9, Iss 1, Pp 50-57 (2017)
L-type calcium channel CaV1.2 plays an essential role in cardiac function. The gain-of-function mutations in CaV1.2 have been reported to be associated with Timothy syndrome, a disease characterized by QT prolongation and syndactyly. Previously we de
Externí odkaz:
https://doaj.org/article/e83c48c9291d40b38fd509cbf4f957e1
Autor:
Muhammad Riaz, Jinkyu Park, Lorenzo R. Sewanan, Yongming Ren, Jonas Schwan, Subhash K. Das, Pawel T. Pomianowski, Yan Huang, Matthew W. Ellis, Jiesi Luo, Juli Liu, Loujin Song, I-Ping Chen, Caihong Qiu, Masayuki Yazawa, George Tellides, John Hwa, Lawrence H. Young, Lei Yang, Charles C. Marboe, Daniel L. Jacoby, Stuart G. Campbell, Yibing Qyang
Publikováno v:
Circulation
Background: Familial hypertrophic cardiomyopathy (HCM) is the most common inherited cardiac disease and is typically caused by mutations in genes encoding sarcomeric proteins that regulate cardiac contractility. HCM manifestations include left ventri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a76ff451fbfe323dbdddc40644fe8b7
https://doi.org/10.1161/circulationaha.121.056265
https://doi.org/10.1161/circulationaha.121.056265
Autor:
LouJin Song, Ramsey Bekdash, Kumi Morikawa, Jose R. Quejada, Alison D. Klein, Danielle Aina-Badejo, Kazushige Yoshida, Hannah E. Yamamoto, Amy Chalan, Risako Yang, Achchhe Patel, Dario Sirabella, Teresa M. Lee, Leroy C. Joseph, Fuun Kawano, Junco S. Warren, Rajesh K. Soni, John P. Morrow, Masayuki Yazawa
Publikováno v:
Nature Cardiovascular Research. 1:142-156
Some missense gain-of-function mutations in CACNA1C gene, encoding calcium channel CaV1.2, cause a life-threatening form of long QT syndrome named Timothy syndrome, with currently no clinically-effective therapeutics. Here we report that pharmacologi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3e59f9cc45b6942be17a6c67f58ddee
https://doi.org/10.1038/s44161-021-00016-2
https://doi.org/10.1038/s44161-021-00016-2