Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Louise Y.Y. Fong"'
Autor:
K. Leroy, Elizabeth Rybakovsky, James M. Mullin, S. McShane, P. Wong, Erin McDonnell, S. Trembeth, Mary Carmen Valenzano, Elizabeth Richardson, James J Thornton, Ryan Urbas, Jared Lander, Jonathan M. Raines, A. Corcoran, S. Yalamanchili, William Huntington, Gary Newman, B. Etemad, V. Chen, Giancarlo Mercogliano, Marc Zitin, Andrew V. Kossenkov, Louise Y.Y. Fong, Barani Mayilvaganan, A. Mathew, Laura Connor, Gary Daum
Publikováno v:
Dig Dis Sci
BACKGROUND: Chemopreventive effects of zinc for esophageal cancer have been well documented in animal models. This prospective study explores if a similar, potentially chemopreventive action can be seen in Barrett’s esophagus (BE) in humans. AIMS:
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32dd75402b50c75710f9bc9c20003777
https://doi.org/10.1007/s10620-020-06319-x
https://doi.org/10.1007/s10620-020-06319-x
Autor:
Karl J. Smalley, Ruiyan Jing, Sili Fan, Carlo M. Croce, Guidantonio Malagoli Tagliazucchi, Louise Y.Y. Fong, Oliver Fiehn, Joseph Altemus, Cristian Taccioli, Kay Huebner, Alexey Palamarchuk, John L. Farber
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 117, iss 11
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America
Significance ESCC is a deadly disease with few prevention or treatment options. In a dietary Zn deficiency-promoted rat ESCC model with miR-31–controlled inflammation pathway up-regulation, systemic antimiR-31 reduces miR-31 level and inflammation,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0b9f7bf86c61ecc8eb7556a592d2aa8
http://hdl.handle.net/11577/3339098
http://hdl.handle.net/11577/3339098
Autor:
Oliver Fiehn, Johannes F. Fahrmann, Karl J. Smalley, Hansjuerg Alder, Ruiyan Jing, Dinesh Kumar Barupal, Louise Y.Y. Fong, John L. Farber, Carlo M. Croce, Cristian Taccioli
Publikováno v:
Oncotarget
// Louise Y. Fong 1,2,3 , Ruiyan Jing 1 , Karl J. Smalley 2 , Cristian Taccioli 4 , Johannes Fahrmann 5 , Dinesh K. Barupal 5 , Hansjuerg Alder 7 , John L. Farber 1 , Oliver Fiehn 5,6 and Carlo M. Croce 7 1 Department of Pathology, Anatomy & Cell Bio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b943622d62b5ead477d9e66000571c7c
https://doi.org/10.18632/oncotarget.18434
https://doi.org/10.18632/oncotarget.18434
Autor:
Kay Huebner, Oliver Fiehn, Zi-Xuan Wang, Sili Fan, Karl J. Smalley, Hongping Chen, Carlo M. Croce, Ruiyan Jing, John L. Farber, Louise Y.Y. Fong, Hansjuerg Alder, Cristian Taccioli
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 115, iss 47
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America
Significance Prostate cancer in man is associated with Zn loss, citrate metabolite reduction, overexpression of the miR-183-96-182 cluster, and regulation of Zn homeostasis through Zn transporter suppression. Our mechanistic study shows that a low-Zn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e402208eedbe9795b5c1fdc53aff4e0
https://escholarship.org/uc/item/5gz4s3fb
https://escholarship.org/uc/item/5gz4s3fb
Publikováno v:
Aging (Albany NY)
Esophageal squamous cell carcinoma (ESCC) is a deadly disease with a 5-year survival of only 10% [1]. Because of the absence of early symptoms, ESCC is commonly diagnosed at an advanced stage. Thus, the development of new prevention and therapeutic a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2fc09ac59ff691dea72b587f1f5d10d
https://pubmed.ncbi.nlm.nih.gov/27280381
https://pubmed.ncbi.nlm.nih.gov/27280381
Autor:
Morgan S. Schrock, Louise Y.Y. Fong, Donald Quimby, Kay Huebner, Teresa Druck, Xueliang Pan, James Liu, Jin Sun, Rulong Shen, Nicola Zanesi
Publikováno v:
Cancer Medicine
Inadequate dietary Zn consumption increases susceptibility to esophageal and other cancers in humans and model organisms. Since Zn supplementation can prevent cancers in rodent squamous cell carcinoma (SCC) models, we were interested in determining i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a74d7b258d03c0e9070cc52ddb377e80
https://pubmed.ncbi.nlm.nih.gov/27185213
https://pubmed.ncbi.nlm.nih.gov/27185213
Autor:
Karl J. Smalley, Paolo Fadda, John L. Farber, Cristian Taccioli, Hansjuerg Alder, Yubao Jiang, Louise Y.Y. Fong, Carlo M. Croce, Ruiyan Jing
Publikováno v:
Oncotarget
Zinc deficiency (ZD) increases the risk of esophageal squamous cell carcinoma (ESCC), and marginal ZD is prevalent in humans. In rats, marked-ZD (3 mg Zn/kg diet) induces a proliferative esophagus with a 5-microRNA signature (miR-31, -223, -21, -146b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e5202a44af7e0401519fe27a5366e37
http://hdl.handle.net/11577/3222280
http://hdl.handle.net/11577/3222280
Autor:
Yubao Jiang, Karl J. Smalley, Louise Y.Y. Fong, Kay Huebner, Paolo Fadda, Hansjuerg Alder, Hatice Gulcin Ozer, Hongping Chen, Carlo M. Croce, John L. Farber, Cristian Taccioli
Publikováno v:
Carcinogenesis. 33:1736-1744
Zinc deficiency (ZD) increases the risk of esophageal squamous cell carcinoma (ESCC). In a rat model, chronic ZD induces an inflammatory gene signature that fuels ESCC development. microRNAs regulate gene expression and are aberrantly expressed in ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48725c99499242156182308403abf7dd
https://doi.org/10.1093/carcin/bgs204
https://doi.org/10.1093/carcin/bgs204
Autor:
Xueliang Pan, James Liu, Teresa Druck, Louise Y.Y. Fong, Carlo M. Croce, Nicola Zanesi, Jin Sun, Kay Huebner, Donald Quimby, Gerd P. Pfeifer
Publikováno v:
Carcinogenesis. 32:351-358
Zinc deficiency is associated with high incidences of esophageal and other cancers in humans and leads to a highly proliferative hyperplastic condition in the upper gastrointestinal tract in laboratory rodents. Zn replenishment reduces the incidence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ece3baaad4b917324d7311a65e24ebc9
https://doi.org/10.1093/carcin/bgq251
https://doi.org/10.1093/carcin/bgq251
Autor:
Xiuping Liu, Karl J. Smalley, Yubao Jiang, Cristian Taccioli, Hongping Chen, John L. Farber, Carlo M. Croce, Shaogui Wan, Kun Huang, Louise Y.Y. Fong
Publikováno v:
International Journal of Cancer. Journal International du Cancer
Zinc (Zn)-deficiency (ZD) is implicated in the pathogenesis of human oral-esophageal cancers. Previously, we showed that in ZD mice genetic deletion of cyclooxygenase-2 (Cox-2) enhances N-nitrosomethylbenzylamine-induced forestomach carcinogenesis. B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3cc40bd689f44eee4996784d76a662f
https://doi.org/10.1002/ijc.25688
https://doi.org/10.1002/ijc.25688