Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Louise Uoselis"'
Autor:
Benjamin Scott Padman, Thanh Ngoc Nguyen, Louise Uoselis, Marvin Skulsuppaisarn, Lan K. Nguyen, Michael Lazarou
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Selective autophagy receptors are thought to selectively recruit Atg8 positive membranes to cargo via their LIR motif. Here, the authors show the LIR motifs in OPTN and NDP52 are dispensable for selectivity, functioning instead to recruit additional
Externí odkaz:
https://doaj.org/article/e997010551564f7caf61ed3ea0695365
Autor:
Louise Uoselis, Runa Lindblom, Marvin Skulsuppaisarn, Grace Khuu, Thanh N. Nguyen, Danielle L. Rudler, Aleksandra Filipovska, Ralf B. Schittenhelm, Michael Lazarou
Breakdown of mitochondrial proteostasis activates quality control pathways including the mitochondrial unfolded protein response (UPRmt) and PINK1/Parkin mitophagy. However, beyond the upregulation of chaperones and proteases, we have a limited under
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::302415e57e4595459f716be2d25da266
https://doi.org/10.1101/2022.11.30.518286
https://doi.org/10.1101/2022.11.30.518286
Autor:
Christian Behrends, Benjamin S. Padman, Marvin Skulsuppaisarn, Michael Lazarou, Susanne Zellner, Thanh Ngoc Nguyen, Louise Uoselis
SummaryThe sequestration of damaged mitochondria within double-membrane structures termed autophagosomes is a key step of PINK1/Parkin mitophagy. The Atg4 family of proteases are thought to regulate autophagosome formation exclusively by processing t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::44a69106f9137c640f9a40f4e07d9c4f
https://doi.org/10.1101/2020.12.17.422596
https://doi.org/10.1101/2020.12.17.422596
Autor:
Lan K. Nguyen, Thanh Ngoc Nguyen, Benjamin S. Padman, Michael Lazarou, Marvin Skulsuppaisarn, Louise Uoselis
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Nature Communications
Nature Communications
Current models of selective autophagy dictate that autophagy receptors, including Optineurin and NDP52, link cargo to autophagosomal membranes. This is thought to occur via autophagy receptor binding to Atg8 homologs (LC3/GABARAPs) through an LC3 int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::039e1ec5ef01a05dc09242ca5058ae64
https://doaj.org/article/e997010551564f7caf61ed3ea0695365
https://doaj.org/article/e997010551564f7caf61ed3ea0695365
Autor:
Susanne Zellner, Grace Khuu, Louise Uoselis, Benjamin S. Padman, Runa S.J. Lindblom, Marvin Skulsuppaisarn, Thanh Ngoc Nguyen, Michael Lazarou, Emily M. Watts, Wai Kit Lam, Christian Behrends
Publikováno v:
Molecular cell. 81(9)
The sequestration of damaged mitochondria within double-membrane structures termed autophagosomes is a key step of PINK1/Parkin mitophagy. The ATG4 family of proteases are thought to regulate autophagosome formation exclusively by processing the ubiq
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fbbcb8cc6d922c46dc91b7c43384f87
https://pubmed.ncbi.nlm.nih.gov/33773106
https://pubmed.ncbi.nlm.nih.gov/33773106