Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Louise Treanor"'
Autor:
Fabiana Lueoend, Youngchul Song, Beverly Nguyen, Xiaoyan Li, Andreas Raue, Jennifer Brogdon, Glenn Dranoff, Matthew Niederst, Louise Treanor
Publikováno v:
Regular and Young Investigator Award Abstracts.
Autor:
Rao Prabhala, Diego Hernandez Rodriguez, Kenneth C. Anderson, Marc Credi, Lawrence Rispoli, Omar Nadeem, Jacob P. Laubach, Sarah Nikiforow, Kit L. Shaw, Nikhil C. Munshi, Yohei Arihara, Soudeh Ansari, Jerome Ritz, Alejandro Alonso, Serena De Vita, Shuntaro Ikegawa, David Pearson, Clifton C. Mo, Jennifer Marie Mataraza, Anniesha Hack, Adam S. Sperling, Dexiu Bu, Heather Daley, Louise Treanor, David Quinn
Publikováno v:
Blood. 138:3864-3864
Background: Chimeric antigen receptor (CAR)-T cells are highly effective in patients (pts) with multiple myeloma (MM), but duration of response can be limited, and pts with rapidly progressing disease require a fast and reliable CAR-T cell manufactur
Autor:
Keith Mansfield, Dexiu Bu, Paul Bennett, Laura Bradshaw, Xiangen Li, Maria Pinon-Ortiz, Jennifer Brogdon, Xu Zhu, Nathaniel S. Barton, Louise Treanor, Poonam Vaidya, Brian Granda, Carla Guimaraes
Publikováno v:
Blood. 138:2770-2770
Background : Chimeric antigen receptor T cell (CAR-T) therapies for multiple myeloma (MM) targeting B cell maturation antigen (BCMA) have demonstrated promising efficacy; however, many patients with relapsed/refractory (r/r) MM will ultimately relaps
Autor:
Jennifer Brogdon, Jennifer Yang, Boris Engels, Lana Parent, Akash Sohoni, Elena Orlando, Louise Treanor, Jeanne Whalen, Andrew M. Stein, Michael R. Greene, Andrew Price, Matthew J. Niederst, Xu Zhu
Publikováno v:
Blood. 138:2848-2848
Background: Extended T-cell culture periods in vitro deplete the CAR-T final product of naive and stem cell memory T-cell (T scm) subpopulations that are associated with improved antitumor efficacy. YTB323 is an autologous CD19-directed CAR-T cell th
Publikováno v:
Treanor, L, Bellamy, C, Harrison, D J & Prost, S 2010, ' Independent regulation of P53 stabilisation and activation after Rb deletion in primary epithelial cells ', International journal of oncology, vol. 37, no. 1, pp. 31-9 . https://doi.org/10.3892/ijo_00000650
We have previously reported that deletion of the retinoblastoma gene Rb leads to rapid but transient p53 stabilisation. We investigated here the pathways involved. We show that upon Rb-deletion dysregulated E2F activates p19(ARF) expression that loca
Publikováno v:
Oncogene. 23(8)
Using Cre-Lox technology to inducibly delete Rb from wild-type, p21- and/or p53-deficient primary hepatocytes, we investigated the role of p53, p21 and pRb in the regulation of liver cell proliferation, polyploidization and death. These cellular deci