Výsledky vyhledávání - "Louise Stögbauer"

Expression of decitabine-targeted oncogenes in meningiomas in vivo

Autor: Julian Canisius, Andrea Wagner, Eva Christina Bunk, Dorothee Cäcilia Spille, Louise Stögbauer, Oliver Grauer, Katharina Hess, Christian Thomas, Werner Paulus, Walter Stummer, Volker Senner, Benjamin Brokinkel

Publikováno v: Neurosurgical Review. 45:2767-2775

Treatment of meningiomas refractory to surgery and irradiation is challenging and effective chemotherapies are still lacking. Recently, in vitro analyses revealed decitabine (DCT, 5-aza-2’–deoxycytidine) to be effective in high-grade meningiomas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::708390f709ccaf56f4fe436b2efbf8ce
https://doi.org/10.1007/s10143-022-01789-1

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Efficacy of decitabine in malignant meningioma cells: relation to promoter demethylation of distinct tumor suppressor and oncogenes and independence from TERT

Autor: Andrea Wagner, Eva Christine Bunk, Julian Canisius, Christian Thomas, Nils Warneke, Oliver Grauer, Louise Stögbauer, Walter Stummer, Benjamin Brokinkel, Werner Paulus, Volker Senner

Publikováno v: Journal of Neurosurgery. 135:845-854

OBJECTIVE Chemotherapeutic options for meningiomas refractory to surgery or irradiation are largely unknown. Human telomerase reverse transcriptase (hTERT) promoter methylation with subsequent TERT expression and telomerase activity, key features in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94e5ddbae5c1f32693d582dd35ea6c3b
https://doi.org/10.3171/2020.7.jns193097

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Validating a new generation filter system for visualizing 5-ALA-induced PpIX fluorescence in malignant glioma surgery: a proof of principle study

Autor: Walter Stummer, Louise Stögbauer, Nils Warneke, Astrid Jeibmann, Eric Suero Molina

Publikováno v: Acta Neurochirurgica

Background The BLUE 400 filter system (Carl Zeiss Meditec, Oberkochen, Germany) has provided visualization of 5-ALA-induced fluorescence-guided surgery for more than 20 years. Nevertheless, constraints, e.g., limited background discrimination during

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3357903b84e4d313326d33f1174c2b9a
http://europepmc.org/articles/PMC7066295

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Second-look strokectomy of cerebral infarction areas in patients with severe herniation

Autor: Peter B. Sporns, Walter Stummer, Christian Ewelt, Markus Holling, Michael Müther, Michael Schwake, Uta Hanning, Jens Minnerup, Rainer Dziewas, Louise Stögbauer, Stephanie Schipmann

Publikováno v: Journal of Neurosurgery. 132:1-9

OBJECTIVEDecompressive craniectomies (DCs) are performed on patients suffering large cerebral infarctions. The efficacy of this procedure has been demonstrated in several trials. In some cases, however, this procedure alone is not sufficient and pati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a85ce1ed6b850bfc6a955b2b3a923481
https://doi.org/10.3171/2018.8.jns18692

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Telomerase activity, TERT expression, hTERT promoter alterations, and alternative lengthening of the telomeres (ALT) in meningiomas – a systematic review

Autor: Volker Senner, Louise Stögbauer, Benjamin Brokinkel, Walter Stummer

Publikováno v: Neurosurgical Review. 43:903-910

Telomerase activity and (human) Telomerase Reverse Transcriptase (hTERT) expression are considered hallmarks in oncogenesis of neoplasms and are upregulated by alterations of the hTERT promoter. In meningiomas, numerous studies investigated hTERT exp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f791a4364fd260ca0df44749f218fb09
https://doi.org/10.1007/s10143-019-01087-3

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Combination of ALA-induced fluorescence-guided resection and intraoperative open photodynamic therapy for recurrent glioblastoma: case series on a promising dual strategy for local tumor control

Autor: Walter Stummer, Oliver Grauer, Benjamin Brokinkel, Markus Holling, Louise Stögbauer, Sebastian Zimmer, Michael Müther, Stephanie Schipmann, Nils Warneke, Eric Suero Molina

Publikováno v: Journal of neurosurgery.

OBJECTIVEHigh-grade glioma (HGG) prognosis remains dismal, with inevitable, mostly local recurrence. Regimens for improving local tumor control are therefore needed. Photodynamic therapy (PDT) using porfimer sodium has been investigated but was aband

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8663b103d0be32c41c1ac4d8de770749
https://pubmed.ncbi.nlm.nih.gov/31978877

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