Výsledky vyhledávání - "Louise Sladen"

Akademický článek

Assessing the Relationship between Lung Density and Function with Oxygen-Enhanced Magnetic Resonance Imaging in a Mouse Model of Emphysema.

Autor: Magdalena Zurek, Louise Sladen, Edvin Johansson, Marita Olsson, Sonya Jackson, Hui Zhang, Gaell Mayer, Paul D Hockings

Publikováno v: PLoS ONE, Vol 11, Iss 3, p e0151211 (2016)

PURPOSE:A magnetic resonance imaging method is presented that allows for the simultaneous assessment of oxygen delivery, oxygen uptake, and parenchymal density. The technique is applied to a mouse model of porcine pancreatic elastase (PPE) induced lu

Externí odkaz: https://doaj.org/article/feba9900868f4b0095231007df78a608

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Regulatory respiratory data refinement with reduced animal usage

Autor: Aileen Milne, Louise Sladen, Kevin Norton, Rommel Matheson

Publikováno v: Journal of pharmacological and toxicological methods. 93

Introduction Assessment of effects of potential drug candidates on the respiratory system is part of the regulatory preclinical safety assessment conducted prior to first in human trials (FTIH). Commonly, this is carried out utilizing head out plethy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8509aaf1ee948a9e0cc0506e3249db02
https://pubmed.ncbi.nlm.nih.gov/29580876

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