Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Louise Scrocchi"'
Autor:
Bettina Platt, Benjamin Drever, David Koss, Sandra Stoppelkamp, Amar Jyoti, Andrea Plano, Aneli Utan, Georgina Merrick, Duncan Ryan, Valeria Melis, Hong Wan, Marco Mingarelli, Emanuele Porcu, Louise Scrocchi, Andy Welch, Gernot Riedel
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e27068 (2011)
Late-stage neuropathological hallmarks of Alzheimer's disease (AD) are β-amyloid (βA) and hyperphosphorylated tau peptides, aggregated into plaques and tangles, respectively. Corresponding phenotypes have been mimicked in existing transgenic mice,
Externí odkaz:
https://doaj.org/article/eb83b209553540a58503fbc30b7b2154
Autor:
An Tanghe, Annelies Termont, Pascal Merchiers, Stephan Schilling, Hans-Ulrich Demuth, Louise Scrocchi, Fred Van Leuven, Gerard Griffioen, Tom Van Dooren
Publikováno v:
International Journal of Alzheimer's Disease, Vol 2010 (2010)
The APP[V717I] London (APP-Ld) mouse model recapitulates important pathological and clinical hallmarks of Alzheimer's disease (AD) and is therefore a valuable paradigm for evaluating therapeutic candidates. Historically, both the parenchymal and vasc
Externí odkaz:
https://doaj.org/article/a5197c7e75b44c5e80b34ab6b80b4a30
Autor:
Min Nian, Louise Scrocchi, Yuanfang Liu, Jumana Saleh, Robin P. Boushey, Daniel J. Drucker, Julie A. Lovshin, Laurie L. Baggio, Feisal Adatia, Bernardo Yusta
Publikováno v:
Annals of the New York Academy of Sciences. 921:226-232
Glucagon-like peptides 1 and 2 (GLP-1 and GLP-2) are coencoded within a single mammalian proglucagon precursor, and are liberated in the intestine and brain. GLP-1 exerts well known actions on islet hormone secretion, gastric emptying, and food intak
Autor:
Winnie Lee, Gerhard Koenig, Mary Jo Miller, Zhiyong Yang, Hilliary Hodgdon, Daniel Havas, Emily A. Freeman, Veerle Vulsteke, Holger Patzke, Liza Leventhal, Richard Chesworth, Sarah C. Hopp, Faris Albayya, Jean Francois Blain, Zhiming Tu, Michael K. Ahlijanian, Lori Hrdlicka, Louise Scrocchi, Scott Nolan, Melody Wen, Henrik Zetterberg, Dorothy G. Flood, Don Costa, Kevin M. Felsenstein, Erik Portelius, Kathryn Rogers, Gideon Shapiro, Birgit Hutter-Paier, Bart De Strooper, Darcie Spaulding
Publikováno v:
Molecular Neurodegeneration, Vol 7, Iss 1, p 61 (2012)
Molecular Neurodegeneration
Molecular Neurodegeneration
Background A hallmark of Alzheimer’s disease is the presence of senile plaques in human brain primarily containing the amyloid peptides Aβ42 and Aβ40. Many drug discovery efforts have focused on decreasing the production of Aβ42 through γ-secre
Autor:
Vivian Lee, Masoud Yousefi, Marni D. Uger, Ryan Demers, Neil R. Cashman, Louise Scrocchi, Hui Chen, Elizabeth Karaskov
Publikováno v:
Alzheimer's & Dementia. 8
Autor:
Kaj Blennow, Marty Lehto, Marni D. Uger, Neil R. Cashman, Louise Scrocchi, Vivian Lee, Hui Chen, Elizabeth Karaskov, Henrik Zetterberg
Publikováno v:
Alzheimer's & Dementia. 7
Autor:
Sandra Stoppelkamp, Aneli Utan, Duncan Ryan, Bettina Platt, Hong Wan, Marco Mingarelli, Louise Scrocchi, Gernot Riedel, David J. Koss, Amar Jyoti, Emanuele Porcu, Benjamin D. Drever, Valeria Melis, Andrew Welch, Georgina Merrick, Andrea Plano
Publikováno v:
PLoS ONE
PLoS ONE, Vol 6, Iss 11, p e27068 (2011)
PLoS ONE, Vol 6, Iss 11, p e27068 (2011)
Late-stage neuropathological hallmarks of Alzheimer's disease (AD) are β-amyloid (βA) and hyperphosphorylated tau peptides, aggregated into plaques and tangles, respectively. Corresponding phenotypes have been mimicked in existing transgenic mice,
Autor:
Stephan Schilling, Tom Van Dooren, Fred Van Leuven, An Tanghe, Annelies Termont, Louise Scrocchi, Pascal Merchiers, Gerard Griffioen, Hans-Ulrich Demuth
Publikováno v:
International Journal of Alzheimer's Disease, Vol 2010 (2010)
International Journal of Alzheimer's Disease
International Journal of Alzheimer's Disease
The APP[V717I] London (APP-Ld) mouse model recapitulates important pathological and clinical hallmarks of Alzheimer's disease (AD) and is therefore a valuable paradigm for evaluating therapeutic candidates. Historically, both the parenchymal and vasc
Autor:
Kalpna Desai, Tina Catalano, Devanshi Maharaja, Jason Dowd, Louise Scrocchi, Stephen Brokx, Sanyukta Kher
Publikováno v:
Journal of Clinical Oncology. 33:e13534-e13534
e13528 Background: Biosimilar development involves extensive analytical testing to ensure comparability to the reference medicinal product to support the demonstration of similarity in terms of cli...
Autor:
Stephen Brokx, Kalpna Desai, Sanyukta Kher, Tina Catalano, Devanshi Maharaja, Louise Scrocchi, Jason Dowd
Publikováno v:
Journal of Clinical Oncology. 33:e13528-e13528