Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Louise P Walker"'
Autor:
Sarah Lincoln, Mariet Allen, Claire L Cox, Louise P Walker, Kimberly Malphrus, Yushi Qiu, Thuy Nguyen, Christopher Rowley, Naomi Kouri, Julia Crook, V Shane Pankratz, Samuel Younkin, Linda Younkin, Minerva Carrasquillo, Fanggeng Zou, Samer O Abdul-Hay, Wolfdieter Springer, Sigrid B Sando, Jan O Aasly, Maria Barcikowska, Zbigniew K Wszolek, Jada M Lewis, Dennis Dickson, Neill R Graff-Radford, Ronald C Petersen, Elizabeth Eckman, Steven G Younkin, Nilüfer Ertekin-Taner
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e64164 (2013)
Leucine rich repeat transmembrane protein 3 (LRRTM3) is member of a synaptic protein family. LRRTM3 is a nested gene within α-T catenin (CTNNA3) and resides at the linkage peak for late-onset Alzheimer's disease (LOAD) risk and plasma amyloid β (A
Externí odkaz:
https://doaj.org/article/4b8767a6bff4419787f56889d10ad6f1
Autor:
Adriana Oliveira Manfiolli, Thaila Fernanda dos Reis, Leandro José de Assis, Patrícia Alves de Castro, Lilian Pereira Silva, Juliana I. Hori, Louise A. Walker, Carol A. Munro, Ranjith Rajendran, Gordon Ramage, Gustavo H. Goldman
Publikováno v:
The Cell Surface, Vol 6, Iss , Pp 100035- (2020)
Externí odkaz:
https://doaj.org/article/be86199470f940c3aa3b2f6fd01ebc34
Autor:
Ning-Ning Liu, Maikel Acosta-Zaldívar, Wanjun Qi, Joann Diray-Arce, Louise A. Walker, Theodore J. Kottom, Rachel Kelly, Min Yuan, John M. Asara, Jessica Ann Lasky-Su, Ofer Levy, Andrew H. Limper, Neil A. R. Gow, Julia R. Köhler
Publikováno v:
mBio, Vol 11, Iss 2 (2020)
ABSTRACT The Candida albicans high-affinity phosphate transporter Pho84 is required for normal Target of Rapamycin (TOR) signaling, oxidative stress resistance, and virulence of this fungal pathogen. It also contributes to C. albicans’ tolerance of
Externí odkaz:
https://doaj.org/article/dd3ae8e11a964f948c0d20db254e5bb3
Autor:
Lucian Duvenage, Louise A. Walker, Aleksandra Bojarczuk, Simon A. Johnston, Donna M. MacCallum, Carol A. Munro, Campbell W. Gourlay
Publikováno v:
mBio, Vol 10, Iss 1 (2019)
ABSTRACT The human fungal pathogen Candida albicans requires respiratory function for normal growth, morphogenesis, and virulence. Mitochondria therefore represent an enticing target for the development of new antifungal strategies. This possibility
Externí odkaz:
https://doaj.org/article/d09b6a0106be494e92b07724b0b9b1ca
Autor:
Michelle D. Leach, Rhys A. Farrer, Kaeling Tan, Zhengqiang Miao, Louise A. Walker, Christina A. Cuomo, Robert T. Wheeler, Alistair J. P. Brown, Koon Ho Wong, Leah E. Cowen
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
The transcription factor Hsf1 and the molecular chaperone Hsp90 modulate the heat shock response in the pathogen Candida albicans. Here, Leach et al. reveal a complex interplay between the two factors that regulates the expression of genes involved i
Externí odkaz:
https://doaj.org/article/5a61a55cffcb49418d894c6ff91cee45
Autor:
Leila M Lopes-Bezerra, Louise A Walker, Gustavo Niño-Vega, Héctor M Mora-Montes, Gabriela W P Neves, Hector Villalobos-Duno, Laura Barreto, Karina Garcia, Bernardo Franco, José A Martínez-Álvarez, Carol A Munro, Neil A R Gow
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 12, Iss 3, p e0006169 (2018)
Sporotrichosis is a subcutaneous mycosis caused by pathogenic species of the Sporothrix genus. A new emerging species, Sporothrix brasiliensis, is related to cat-transmitted sporotrichosis and has severe clinical manifestations. The cell wall of path
Externí odkaz:
https://doaj.org/article/1b33ae0f297443c6899c14afbdd03645
Autor:
Iuliana V. Ene, Louise A. Walker, Marion Schiavone, Keunsook K. Lee, Hélène Martin-Yken, Etienne Dague, Neil A. R. Gow, Carol A. Munro, Alistair J. P. Brown
Publikováno v:
mBio, Vol 6, Iss 4 (2015)
ABSTRACT The fungal cell wall confers cell morphology and protection against environmental insults. For fungal pathogens, the cell wall is a key immunological modulator and an ideal therapeutic target. Yeast cell walls possess an inner matrix of inte
Externí odkaz:
https://doaj.org/article/5674c924328c492783abe0c10a3ab296
Autor:
Margherita Bertuzzi, Markus Schrettl, Laura Alcazar-Fuoli, Timothy C Cairns, Alberto Muñoz, Louise A Walker, Susanne Herbst, Maryam Safari, Angela M Cheverton, Dan Chen, Hong Liu, Shinobu Saijo, Natalie D Fedorova, Darius Armstrong-James, Carol A Munro, Nick D Read, Scott G Filler, Eduardo A Espeso, William C Nierman, Hubertus Haas, Elaine M Bignell
Publikováno v:
PLoS Pathogens, Vol 11, Iss 6, p e1004943 (2015)
Externí odkaz:
https://doaj.org/article/c880268257a74b16a9be6c171f0b5a5e
Autor:
Judith M. Bain, Johanna Louw, Leanne E. Lewis, Blessing Okai, Catriona A. Walls, Elizabeth R. Ballou, Louise A. Walker, Delyth Reid, Carol A. Munro, Alistair J. P. Brown, Gordon D. Brown, Neil A. R. Gow, Lars P. Erwig
Publikováno v:
mBio, Vol 5, Iss 6 (2014)
ABSTRACT Candida albicans is a major life-threatening human fungal pathogen in the immunocompromised host. Host defense against systemic Candida infection relies heavily on the capacity of professional phagocytes of the innate immune system to ingest
Externí odkaz:
https://doaj.org/article/330d9e9e688940309c726a225cc2763d
Autor:
Margherita Bertuzzi, Markus Schrettl, Laura Alcazar-Fuoli, Timothy C Cairns, Alberto Muñoz, Louise A Walker, Susanne Herbst, Maryam Safari, Angela M Cheverton, Dan Chen, Hong Liu, Shinobu Saijo, Natalie D Fedorova, Darius Armstrong-James, Carol A Munro, Nick D Read, Scott G Filler, Eduardo A Espeso, William C Nierman, Hubertus Haas, Elaine M Bignell
Publikováno v:
PLoS Pathogens, Vol 10, Iss 10, p e1004413 (2014)
Destruction of the pulmonary epithelium is a major feature of lung diseases caused by the mould pathogen Aspergillus fumigatus. Although it is widely postulated that tissue invasion is governed by fungal proteases, A. fumigatus mutants lacking indivi
Externí odkaz:
https://doaj.org/article/eb8eb45ee83a4e99a63533f7c78440cd