Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Louise Orcheston-Findlay"'
Autor:
Thomas James Grundy, Louise Orcheston-Findlay, Eshana de Silva, Thuvarahan Jegathees, Victoria Prior, Farhana Amy Sarker, Geraldine Margaret O’Neill
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Mechanical forces created by the extracellular environment regulate biochemical signals that modulate the inter-related cellular phenotypes of morphology, proliferation, and migration. A stiff microenvironment induces glioblastoma (GBM) cell
Externí odkaz:
https://doaj.org/article/c648f2e40e8244b4ba522d419fb427a2
Autor:
Louise Orcheston-Findlay, Samuel Bax, Robert Utama, Martin Engel, Dinisha Govender, Geraldine O’Neill
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 6, p 2962 (2021)
The life expectancy of patients with high-grade glioma (HGG) has not improved in decades. One of the crucial tools to enable future improvement is advanced models that faithfully recapitulate the tumour microenvironment; they can be used for high-thr
Externí odkaz:
https://doaj.org/article/4a8b17cd1ca74228bd50b17bc286d566
Autor:
Azadeh Hashemi, Fanny de Decker, Louise Orcheston-Findlay, M. Azam Ali, Maan M. Alkaisi, Volker Nock
Publikováno v:
AIP Advances, Vol 7, Iss 11, Pp 115019-115019-10 (2017)
This work introduces casein microstructures with surface features as a biodegradable biomedical platform technology for enhancing tissue-engineering applications. An optimized fabrication process is presented to reduce the hydrophobicity of intermedi
Externí odkaz:
https://doaj.org/article/242a813ae06e4d4b80421fcaa85463a4
Autor:
Dinisha Govender, Samuel Bax, Geraldine M. O'Neill, Martin Engel, Robert H. Utama, Louise Orcheston-Findlay
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 2962, p 2962 (2021)
International Journal of Molecular Sciences, Vol 22, Iss 2962, p 2962 (2021)
The life expectancy of patients with high-grade glioma (HGG) has not improved in decades. One of the crucial tools to enable future improvement is advanced models that faithfully recapitulate the tumour microenvironment; they can be used for high-thr
Publikováno v:
Microelectronic Engineering. 195:107-113
Standard cancer lab models lack many attributes of the in-vivo cancer microenvironment. Oxygen levels for example are not commonly controlled in 2D cell-culture well plate experiments. However, low O2 (hypoxia) in particular is common in cancerous ti
Publikováno v:
International Journal of Nanotechnology. 15:753
Cancer cells resist some anti-cancer drugs in a hypoxic environment, which is often present in-vivo due to high proliferation rates and inadequate vasculature in dense tumour cores. Oxygen control and measurement are therefore valuable tools in cultu
Autor:
Maan M. Alkaisi, Volker Nock, Azadeh Hashemi, Fanny de Decker, Louise Orcheston-Findlay, M. Azam Ali
Publikováno v:
AIP Advances, Vol 7, Iss 11, Pp 115019-115019-10 (2017)
This work introduces casein microstructures with surface features as a biodegradable biomedical platform technology for enhancing tissue-engineering applications. An optimized fabrication process is presented to reduce the hydrophobicity of intermedi