Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Louise Mannerås Holm"'
Autor:
Antonio Molinaro, Robert Caesar, Louise Mannerås Holm, Valentina Tremaroli, Patrice D. Cani, Fredrik Bäckhed
Publikováno v:
Molecular Metabolism, Vol 6, Iss 11, Pp 1371-1380 (2017)
Objective: Gut microbiota modulates adiposity and glucose metabolism in humans and mice. Here we investigated how colonization of germ-free (GF) mice affects kinetics of adiposity and glucose metabolism. Methods: Adiposity and glucose metabolism were
Externí odkaz:
https://doaj.org/article/81368eccf9244e549620d9d90f6602e3
Autor:
Linda Engström Ruud, Ferran Font-Gironès, Joanna Zajdel, Lara Kern, Júlia Teixidor-Deulofeu, Louise Mannerås-Holm, Alba Carreras, Barbara Becattini, Andreas Björefeldt, Eric Hanse, Henning Fenselau, Giovanni Solinas, Jens C. Brüning, Thomas F. Wunderlich, Fredrik Bäckhed, Johan Ruud
Publikováno v:
Cell Reports, Vol 43, Iss 4, Pp 113960- (2024)
Summary: GFRAL-expressing neurons actuate aversion and nausea, are targets for obesity treatment, and may mediate metformin effects by long-term GDF15-GFRAL agonism. Whether GFRAL+ neurons acutely regulate glucose and energy homeostasis is, however,
Externí odkaz:
https://doaj.org/article/aa3d323435254270b9519bdc32c22457
Autor:
Emmani B.M. Nascimento, Louise Mannerås-Holm, Alexander V. Chibalin, Marie Björnholm, Juleen R. Zierath
Publikováno v:
Journal of Lipid Research, Vol 59, Iss 2, Pp 273-282 (2018)
Conversion of diacylglycerol to phosphatidic acid is mediated by diacylglycerol kinases (DGKs), with DGKα specifically linked to adaptive immune responses. We determined the role of DGKα in obesity and inflammatory responses to a high-fat diet (HFD
Externí odkaz:
https://doaj.org/article/af6160f27775468b9fc3787c521c2c23
Autor:
Louise Mannerås-Holm, Milena Schönke, Joseph T. Brozinick, Laurène Vetterli, Hai-Hoang Bui, Philip Sanders, Emmani B.M. Nascimento, Marie Björnholm, Alexander V. Chibalin, Juleen R. Zierath
Publikováno v:
Journal of Lipid Research, Vol 58, Iss 5, Pp 907-915 (2017)
Diacylglycerol kinases (DGKs) catalyze the phosphorylation and conversion of diacylglycerol (DAG) into phosphatidic acid. DGK isozymes have unique primary structures, expression patterns, subcellular localizations, regulatory mechanisms, and DAG pref
Externí odkaz:
https://doaj.org/article/2bf3b5d7e0a349b4bf872fc42ccb5f83
Autor:
Thi Phuong Nam Bui, Robert Puschmann, Willem M. deVos, Louise Mannerås-Holm, Antonio Dario Troise, Dorothea Fiedler, Hao Wu, Fredrik Bäckhed, Sjef Boeren, Bart Nijsse
Publikováno v:
Nature communications 12 (2021). doi:10.1038/s41467-021-25081-w
info:cnr-pdr/source/autori:Bui T.P.N.; Manneras-Holm L.; Puschmann R.; Wu H.; Troise A.D.; Nijsse B.; Boeren S.; Backhed F.; Fiedler D.; deVos W.M./titolo:Conversion of dietary inositol into propionate and acetate by commensal Anaerostipes associates with host health/doi:10.1038%2Fs41467-021-25081-w/rivista:Nature communications/anno:2021/pagina_da:/pagina_a:/intervallo_pagine:/volume:12
Nature Communications, 12(1)
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Nature Communications 12 (2021) 1
Bui, T P N, Mannerås-Holm, L, Puschmann, R, Wu, H, Troise, A D, Nijsse, B, Boeren, S, Bäckhed, F, Fiedler, D & deVos, W M 2021, ' Conversion of dietary inositol into propionate and acetate by commensal Anaerostipes associates with host health ', Nature Communications, vol. 12, no. 1, 4798 . https://doi.org/10.1038/s41467-021-25081-w
info:cnr-pdr/source/autori:Bui T.P.N.; Manneras-Holm L.; Puschmann R.; Wu H.; Troise A.D.; Nijsse B.; Boeren S.; Backhed F.; Fiedler D.; deVos W.M./titolo:Conversion of dietary inositol into propionate and acetate by commensal Anaerostipes associates with host health/doi:10.1038%2Fs41467-021-25081-w/rivista:Nature communications/anno:2021/pagina_da:/pagina_a:/intervallo_pagine:/volume:12
Nature Communications, 12(1)
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Nature Communications 12 (2021) 1
Bui, T P N, Mannerås-Holm, L, Puschmann, R, Wu, H, Troise, A D, Nijsse, B, Boeren, S, Bäckhed, F, Fiedler, D & deVos, W M 2021, ' Conversion of dietary inositol into propionate and acetate by commensal Anaerostipes associates with host health ', Nature Communications, vol. 12, no. 1, 4798 . https://doi.org/10.1038/s41467-021-25081-w
We describe the anaerobic conversion of inositol stereoisomers to propionate and acetate by the abundant intestinal genus Anaerostipes. A inositol pathway was elucidated by nuclear magnetic resonance using [13C]-inositols, mass spectrometry and prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f8bdf9819c4ff11b00b4cd5e1904a3d
https://publications.cnr.it/doc/457400
https://publications.cnr.it/doc/457400
Autor:
Fazliana Mansor, Harvest F. Gu, Claes-Göran Östenson, Louise Mannerås-Holm, Elisabet Stener-Victorin, Wan Nazaimoon Wan Mohamud
Publikováno v:
Advances in Pharmacological Sciences, Vol 2013 (2013)
Peroxisome proliferator-activated receptor gamma (PPARgamma) is a ligand-activated transcription factor that regulates lipid and glucose metabolism. We investigated the effects of Labisia pumila (LP) standardized water extract on PPARgamma transcript
Externí odkaz:
https://doaj.org/article/f839418dba804e9eb6134196f7376220
Autor:
Alexander V. Chibalin, Louise Mannerås-Holm, Marie Björnholm, Juleen R. Zierath, Emmani B.M. Nascimento
Publikováno v:
Journal of Lipid Research, Vol 59, Iss 2, Pp 273-282 (2018)
Conversion of diacylglycerol to phosphatidic acid is mediated by diacylglycerol kinases (DGKs), with DGKα specifically linked to adaptive immune responses. We determined the role of DGKα in obesity and inflammatory responses to a high-fat diet (HFD
Autor:
Christina N. Heiss, Randy J. Seeley, Ying Shiuan Lee, Fredrik Bäckhed, Anna Håkansson Gladh, Daniel J. Drucker, Louise Mannerås-Holm, Julia Serrano-Lobo, Louise E. Olofsson
Publikováno v:
Heiss, C N, Mannerås-Holm, L, Lee, Y S, Serrano-Lobo, J, Håkansson Gladh, A, Seeley, R J, Drucker, D J, Bäckhed, F & Olofsson, L E 2021, ' The gut microbiota regulates hypothalamic inflammation and leptin sensitivity in Western diet-fed mice via a GLP-1R-dependent mechanism ', Cell Reports, vol. 35, no. 8, 109163 . https://doi.org/10.1016/j.celrep.2021.109163
Mice lacking a microbiota are protected from diet-induced obesity. Previous studies have shown that feeding a Western diet causes hypothalamic inflammation, which in turn can lead to leptin resistance and weight gain. Here, we show that wild-type (WT
Autor:
Hai-Hoang Bui, Laurène Vetterli, Juleen R. Zierath, Milena Schönke, Emmani B.M. Nascimento, Alexander V. Chibalin, Philip E. Sanders, Louise Mannerås-Holm, Marie Björnholm, Joseph T. Brozinick
Publikováno v:
Journal of Lipid Research, Vol 58, Iss 5, Pp 907-915 (2017)
Diacylglycerol kinases (DGKs) catalyze the phosphorylation and conversion of diacylglycerol (DAG) into phosphatidic acid. DGK isozymes have unique primary structures, expression patterns, subcellular localizations, regulatory mechanisms, and DAG pref
Autor:
Filipe, De Vadder, Estelle, Grasset, Louise, Mannerås Holm, Gérard, Karsenty, Andrew J, Macpherson, Louise E, Olofsson, Fredrik, Bäckhed
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 115(25)
The enteric nervous system (ENS) is crucial for essential gastrointestinal physiologic functions such as motility, fluid secretion, and blood flow. The gut is colonized by trillions of bacteria that regulate host production of several signaling molec