Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Louise Laverick"'
Autor:
Wei Z. Yeh, Rodney Lea, Jim Stankovich, Sandeep Sampangi, Louise Laverick, Anneke Van der Walt, Vilija Jokubaitis, Melissa Gresle, Helmut Butzkueven
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract Vitamin D deficiency is a risk factor for developing multiple sclerosis (MS). However, the immune effects of vitamin D in people with MS are not well understood. We analyzed transcriptomic datasets generated by RNA sequencing of immune cell
Externí odkaz:
https://doaj.org/article/3d43419fa22447388647463f63795ebd
Autor:
Vicki E. Maltby, Rodney A. Lea, Sean Burnard, Alexandre Xavier, Thao Van Cao, Nicole White, Daniel Kennedy, Kira Groen, Katherine A. Sanders, Rebecca Seeto, Samara Bray, Melissa Gresle, Louise Laverick, Helmut Butzkueven, Rodney J. Scott, Jeannette Lechner-Scott
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Abstract The pathology of progressive multiple sclerosis (MS) is poorly understood. We have previously assessed DNA methylation in the CD4+ T cells of relapsing–remitting (RR) MS patients compared to healthy controls and identified differentially m
Externí odkaz:
https://doaj.org/article/8d27ddf73fb74666a6a7c7b44026b9c1
Autor:
Michele D Binder, Andrew D Fox, Daniel Merlo, Laura J Johnson, Lauren Giuffrida, Sarah E Calvert, Rainer Akkermann, Gerry Z M Ma, ANZgene, Ashwyn A Perera, Melissa M Gresle, Louise Laverick, Grace Foo, Marzena J Fabis-Pedrini, Timothy Spelman, Margaret A Jordan, Alan G Baxter, Simon Foote, Helmut Butzkueven, Trevor J Kilpatrick, Judith Field
Publikováno v:
PLoS Genetics, Vol 12, Iss 3, p e1005853 (2016)
Multiple Sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system. The risk of developing MS is strongly influenced by genetic predisposition, and over 100 loci have been established as associated with susceptibili
Externí odkaz:
https://doaj.org/article/0cd521e396da40b7bb93def308a10e36
Autor:
Judith Field, Fernando Shahijanian, Stephen Schibeci, Australia and New Zealand MS Genetics Consortium (ANZgene), Laura Johnson, Melissa Gresle, Louise Laverick, Grant Parnell, Graeme Stewart, Fiona McKay, Trevor Kilpatrick, Helmut Butzkueven, David Booth
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0127080 (2015)
Human genetic and animal studies have implicated the costimulatory molecule CD40 in the development of multiple sclerosis (MS). We investigated the cell specific gene and protein expression variation controlled by the CD40 genetic variant(s) associat
Externí odkaz:
https://doaj.org/article/167c9d164d5148e8bf2b8d3c545710f1
Autor:
Vilija G Jokubaitis, Maria Pia Campagna, Omar Ibrahim, Jim Stankovich, Pavlina Kleinova, Fuencisla Matesanz, Daniel Hui, Sara Eichau, Mark Slee, Jeannette Lechner-Scott, Rodney Lea, Trevor J Kilpatrick, Tomas Kalincik, Philip L De Jager, Ashley Beecham, Jacob L McCauley, Bruce V Taylor, Steve Vucic, Louise Laverick, Karolina Vodehnalova, Maria-Isabel García-Sanchéz, Antonio Alcina, Anneke van der Walt, Eva Kubala Havrdova, Guillermo Izquierdo, Nikolaos Patsopoulos, Dana Horakova, Helmut Butzkueven
Publikováno v:
Brain. 146:2316-2331
Multiple sclerosis is a leading cause of neurological disability in adults. Heterogeneity in multiple sclerosis clinical presentation has posed a major challenge for identifying genetic variants associated with disease outcomes. To overcome this chal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3248985acb2a214cb0fd20bf978d9ce
https://doi.org/10.1093/brain/awac449
https://doi.org/10.1093/brain/awac449
Autor:
Vilija G. Jokubaitis, Omar Ibrahim, Jim Stankovich, Pavlina Kleinova, Fuencisla Matesanz, Daniel Hui, Sara Eichau, Mark Slee, Jeannette Lechner-Scott, Rodney Lea, Trevor J Kilpatrick, Tomas Kalincik, Philip L. De Jager, Ashley Beecham, Jacob L. McCauley, Bruce V. Taylor, Steve Vucic, Louise Laverick, Karolina Vodehnalova, Maria-Isabel García-Sanchéz, Antonio Alcina, Anneke van der Walt, Eva Kubala Havrdova, Guillermo Izquierdo, Nikolaos Patsopoulos, Dana Horakova, Helmut Butzkueven
Multiple sclerosis (MS) is a leading cause of neurological disability in adults. Heterogeneity in MS clinical presentation has posed a major challenge for identifying genetic variants associated with disease outcomes. To overcome this challenge, we u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9587907a8d28532da0560bc11f04107d
https://doi.org/10.1101/2022.02.04.22270362
https://doi.org/10.1101/2022.02.04.22270362
Autor:
Rodney A. Lea, Nicole White, Kira Groen, Samara Bray, Jeannette Lechner-Scott, Thao Van Cao, Rodney J. Scott, Melissa Gresle, Vicki E. Maltby, Helmut Butzkueven, Louise Laverick, Daniel W. Kennedy, Sean Burnard, Rebecca G.Y. Seeto, Alexandre Xavier, Katherine A. Sanders
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports
Scientific Reports
The pathology of progressive multiple sclerosis (MS) is poorly understood. We have previously assessed DNA methylation in the CD4+ T cells of relapsing–remitting (RR) MS patients compared to healthy controls and identified differentially methylated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbe3b736a09b09e32d83dc61ca1a93f4
https://doi.org/10.1038/s41598-020-78809-x
https://doi.org/10.1038/s41598-020-78809-x
Autor:
Vilija Jokubaitis, Bruce V. Taylor, Letitia D. Smith, Tim Spelman, Melanie Bahlo, Matthew A. Brown, Jac Charlesworth, Alison Hamlett, Josephine Baker, Alan G. Baxter, Margaret A. Jordan, Jodi Haartsen, Melissa Gresle, Judith Field, Laura J. Johnson, Helmut Butzkueven, Terence P. Speed, Louise Laverick, Jim Stankovich
Publikováno v:
Life Science Alliance
This comprehensive study identifies multiple sclerosis risk expression quantitative trait loci in purified immune cell types.
At least 200 single-nucleotide polymorphisms (SNPs) are associated with multiple sclerosis (MS) risk. A key function th
At least 200 single-nucleotide polymorphisms (SNPs) are associated with multiple sclerosis (MS) risk. A key function th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6badbbfb88413d5996936faf0a3bc2b
https://doi.org/10.26508/lsa.202000650
https://doi.org/10.26508/lsa.202000650
Autor:
Judith Field, Helmut Butzkueven, Jodi Haartsen, Trevor J. Kilpatrick, Michele D. Binder, Melissa Gresle, Lauren Giuffrida, Gerry Z. M. Ma, Louise Laverick
Publikováno v:
Multiple sclerosis journal-experimental, translational and clinical
Background The TAM family of receptor tyrosine kinases (TYRO3, AXL and MERTK) play important roles in modulating innate immune responses and central demyelination. The TAM receptor ligand Protein S (PROS) has also been shown to modulate innate immune
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20fee60afa3726eb65245d89ca8aa1f1
https://pubmed.ncbi.nlm.nih.gov/28607700
https://pubmed.ncbi.nlm.nih.gov/28607700
Autor:
Simon J. Foote, Michele D. Binder, Lauren Giuffrida, Alan G. Baxter, Margaret A. Jordan, Trevor J. Kilpatrick, Daniel Merlo, Tim Spelman, Melissa Gresle, Louise Laverick, Andrew Fox, ANZgene, Marzena J. Fabis-Pedrini, Rainer Akkermann, Sarah E. Calvert, Gerry Z. M. Ma, Ashwyn A. Perera, Laura J. Johnson, Helmut Butzkueven, Grace Foo, Judith Field
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 12, Iss 3, p e1005853 (2016)
PLoS Genetics, Vol 12, Iss 3, p e1005853 (2016)
Multiple Sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system. The risk of developing MS is strongly influenced by genetic predisposition, and over 100 loci have been established as associated with susceptibili
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d05ff4077dd96453286c7a511070c92
http://europepmc.org/articles/PMC4798184
http://europepmc.org/articles/PMC4798184