Use of molnupiravir: a Danish nationwide drug utilization study

Autor: Louise Ladebo, Lotte Rasmussen, Peter Bjødstrup Jensen, Mette Lindahl, Anne Øvrehus, Jesper Hallas, Mette Reilev

Purpose To describe utilization patterns, characteristics of users and prescriber responsibility of the new oral antiviral medication, molnupiravir, indicated for mild-to-moderate COVID-19. Methods Using nationwide registries, we identified all Danis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::26f9c194624b601306b69faf5a904e91
https://doi.org/10.22541/au.167748286.69103593/v1

Changing characteristics over time of individuals receiving COVID-19 vaccines in Denmark:A population-based descriptive study of vaccine uptake

Autor: Mette Reilev, Morten Olesen, Helene Kildegaard, Henrik Støvring, Jacob H. Andersen, Jesper Hallas, Lars Christian Lund, Louise Ladebo, Martin T. Ernst, Per Damkier, Peter B. Jensen, Anton Pottegård, Lotte Rasmussen

Publikováno v: Reilev, M, Olesen, M, Kildegaard, H, Støvring, H, Andersen, J H, Hallas, J, Lund, L C, Ladebo, L, Ernst, M T, Damkier, P, Jensen, P B, Pottegård, A & Rasmussen, L 2022, ' Changing characteristics over time of individuals receiving COVID-19 vaccines in Denmark : A population-based descriptive study of vaccine uptake ', Scandinavian Journal of Public Health, vol. 50, no. 6, pp. 686-692 . https://doi.org/10.1177/14034948221108246

AimsThe Danish authorities implemented a differential rollout of the COVID-19 vaccines where individuals at high risk of COVID-19 were prioritized. We describe the temporal uptake of COVID-19 vaccines and changing characteristics of vaccine recipient

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09bc94fd63cc50082cda5e346d835766
https://pure.au.dk/portal/da/publications/changing-characteristics-over-time-of-individuals-receiving-covid19-vaccines-in-denmark(1e11e3f1-0c20-4bf5-b64a-b5dfb1883ac4).html

Effect of Roux-en-Y gastric bypass on the pharmacokinetic-pharmacodynamic relationships of liquid and controlled-release formulations of oxycodone

Autor: Asbjørn Mohr Drewes, Grzegorz J. Pacyk, Jens Peter Kroustrup, Kenneth T. Kongstad, David J. R. Foster, Ahmad Y. Abuhelwa, Lona L. Christrup, Louise Ladebo, Anne Estrup Olesen

Publikováno v: Ladebo, L, Abuhelwa, A Y, Foster, D J R, Kroustrup, J P, Pacyk, G J, Kongstad, K T, Drewes, A M, Christrup, L L & Olesen, A E 2021, ' Effect of Roux-en-Y gastric bypass on the pharmacokinetic-pharmacodynamic relationships of liquid and controlled-release formulations of oxycodone ', Basic & Clinical Pharmacology & Toxicology, vol. 129, no. 3, pp. 232-245 . https://doi.org/10.1111/bcpt.13634

The physiological changes following Roux-en-Y gastric bypass (RYGB) surgery may impact drug release from mechanistically different controlled-release tablets, making generic substitution inappropriate. This study aimed to characterise the pharmacokin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89b934d490e6e88500dc8fb6a9d66a46
https://hdl.handle.net/11541.2/148124

Chronic abdominal pain and persistent opioid use after bariatric surgery

Autor: Amalie Højmose Simoni, Lona L. Christrup, Louise Ladebo, Søren Paaske Johnsen, Asbjørn Mohr Drewes, Anne Estrup Olesen

Publikováno v: Simoni, A H, Ladebo, L, Christrup, L L, Drewes, A M, Johnsen, S P & Olesen, A E 2020, ' Chronic abdominal pain and persistent opioid use after bariatric surgery ', Scandinavian Journal of Pain, vol. 20, no. 2, pp. 239–251 . https://doi.org/10.1515/sjpain-2019-0092
Simoni, A H, Ladebo, L, Christrup, L L, Drewes, A M, Johnsen, S P & Olesen, A E 2020, ' Chronic abdominal pain and persistent opioid use after bariatric surgery ', Scandinavian Journal of Pain, vol. 20, no. 2, pp. 239-251 . https://doi.org/10.1515/sjpain-2019-0092

Background and aims Bariatric surgery remains a mainstay for treatment of morbid obesity. However, long-term adverse outcomes include chronic abdominal pain and persistent opioid use. The aim of this review was to assess the existing data on prevalen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8d3ed6a1318fa3501c5073806e5ed7a
https://vbn.aau.dk/ws/files/399417009/_18778879_Scandinavian_Journal_of_Pain_Chronic_abdominal_pain_and_persistent_opioid_use_after_bariatric_surgery.pdf

Dicloxacillin induces CYP2C19, CYP2C9 and CYP3A4in vivoandin vitro

Autor: Deanna L. Kroetz, Tore Bjerregaard Stage, Louise Ladebo Rasmussen, Susan Wong, Kim Brøsen, Flemming Nielsen, S. Cyrus Khojasteh, Anton Pottegård, Magnus Graff, Per Damkier

Publikováno v: British Journal of Clinical Pharmacology. 84:510-519

SummaryAim The aim of this study was to study potential cytochrome P450 induction by dicloxacillin. Methods We performed an open-label randomized two-phase 5-drug clinical pharmacokinetic cocktail crossover study in 12 healthy men with and without pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::90b6cd7982aeb7a34790dc561a0a549b
https://doi.org/10.1111/bcp.13467