Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Louise L Dunn"'
Autor:
Kavitha Muthiah, MBChB, PhD, FRACP, FCSANZ, Louise L. Dunn, BSc(Hons), PhD, Hunter Eckford, BMedSci, David Connor, BMedSci(Hons), PhD, Desiree Robson, RN, Peter S. Macdonald, MBBS, FRACP, MD, PhD, Christopher S. Hayward, MD, FRACP
Publikováno v:
JHLT Open, Vol 6, Iss , Pp 100133- (2024)
Bleeding complications are a bane of continuous flow left ventricular assist devices (cfLVAD); gastrointestinal bleeding (GIB) from arteriovenous malformation (AVM) predominating. We hypothesized that shear stress disrupts vascular endothelium alteri
Externí odkaz:
https://doaj.org/article/ccfcaaed3a6e4364b1119944b6badeb3
Autor:
Young Yu, Steven G Wise, Praveesuda L Michael, Daniel V Bax, Gloria S C Yuen, Matti A Hiob, Giselle C Yeo, Elysse C Filipe, Louise L Dunn, Kim H Chan, Hamid Hajian, David S Celermajer, Anthony S Weiss, Martin K C Ng
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0131101 (2015)
The deployment of endovascular implants such as stents in the treatment of cardiovascular disease damages the vascular endothelium, increasing the risk of thrombosis and promoting neointimal hyperplasia. The rapid restoration of a functional endothel
Externí odkaz:
https://doaj.org/article/c94a0facf2934d7e91a094afe368a125
Autor:
Kim H Chan, Philippa J L Simpson, Andy S Yong, Louise L Dunn, Chirapan Chawantanpipat, Chijen Hsu, Young Yu, Anthony C Keech, David S Celermajer, Martin K C Ng
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e93980 (2014)
BACKGROUND: Endothelial progenitor cells (EPCs) are implicated in protection against vascular disease. However, studies using angiography alone have reported conflicting results when relating EPCs to epicardial coronary artery disease (CAD) severity.
Externí odkaz:
https://doaj.org/article/f68aff4e87da4a0f9176a02b3aa5c90e
Autor:
Weiyu Chen, Sergey Tumanov, Christopher P. Stanley, Stephanie M.Y. Kong, James Nadel, Niv Vigder, Darren L. Newington, Xiao Suo Wang, Louise L. Dunn, Roland Stocker
Publikováno v:
Circulation Research. 132:812-827
Background: The rupture of atherosclerotic plaque contributes significantly to cardiovascular disease. Plasma concentrations of bilirubin—a byproduct of heme catabolism—inversely associate with risk of cardiovascular disease, although the link be
Autor:
Yuen Ting Lam, Richard P. Tan, Praveesuda Michael, Nianji Yang, Louise L. Dunn, John P. Cooke, David S. Celermajer, Steven G. Wise, Martin K.C. Ng
Publikováno v:
Microvascular research. 143
Endothelial dysfunction, hallmarked by an imbalance between vasoconstriction and vasorelaxation, is associated with diabetes. Thioredoxin Interacting protein (TXNIP), controlled by an exquisitely glucose sensitive gene, is increasingly recognized for
Autor:
Weiyu Chen, Cacang Suarna, Sergey Tumanov, Louise L. Dunn, David E. James, James Cantley, Roland Stocker, Daniel J. Fazakerley, Taqi Shaik
Publikováno v:
Redox Biology
Redox Biology, Vol 47, Iss, Pp 102152-(2021)
Redox Biology, Vol 47, Iss, Pp 102152-(2021)
Background & aims Plasma concentrations of bilirubin, a product of heme catabolism formed by biliverdin reductase A (BVRA), inversely associate with the risk of metabolic diseases including hepatic steatosis and diabetes mellitus in humans. Bilirubin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::793713a45c5f0879f4dcc5e5bf680108
https://www.repository.cam.ac.uk/handle/1810/330395
https://www.repository.cam.ac.uk/handle/1810/330395
Autor:
James Cantley, Robyn G. Midwinter, Kim H. Chan, Weiyu Chen, Anita Ayer, Ghassan J. Maghzal, Stephanie M.Y. Kong, Louise L. Dunn, Martin K.C. Ng, Roland Stocker, Sergey Tumanov
Publikováno v:
Arteriosclerosis, thrombosis, and vascular biology. 41(1)
Objective: Hmox1 (heme oxygenase-1) is a stress-induced enzyme that catalyzes the degradation of heme to carbon monoxide, iron, and biliverdin. Induction of Hmox1 and its products protect against cardiovascular disease, including ischemic injury. Hmo
Autor:
Kim H. Chan, Louise L. Dunn, Andy S.C. Yong, Philippa J. L. Simpson, Laura Lecce, Martin K.C. Ng, Yuen Ting Lam, Daniel P Sieveking, C. Hsu, David S. Celermajer, Young Yu, Jun Yuan, Steven G. Wise, Renee Chow
Publikováno v:
Endocrinology. 161(5)
Endothelial progenitor cells (EPCs) play a key role in neovascularization and have been linked to improved cardiovascular outcomes. Although there is a well-established inverse relationship between androgen levels and cardiovascular mortality in men,
Publikováno v:
Free Radical Biology and Medicine. 115:156-165
Bilirubin, a byproduct of heme catabolism, has been shown to be an effective lipid-soluble antioxidant in vitro. Bilirubin is able to inhibit free radical chain reactions and protects against oxidant-induced damage in vitro and ex vivo. However, dire
Autor:
Beat H. Walpoth, Jean-Christophe Tille, Sarra de Valence, Marijana Miljkovic-Licina, Roland Stocker, Philippe Hammel, Louise L. Dunn, Beat A. Imhof
Publikováno v:
Wound Repair and Regeneration. 24:1030-1035
Three-dimensional biomimetic scaffolds resembling the native extracellular matrix (ECM) are widely used in tissue engineering, however they often lack optimal bioactive cues needed for acceleration of cell proliferation, neovascularization, and tissu