Zobrazeno 1 - 10
of 88
pro vyhledávání: '"Louise L Dunn"'
Autor:
Kavitha Muthiah, MBChB, PhD, FRACP, FCSANZ, Louise L. Dunn, BSc(Hons), PhD, Hunter Eckford, BMedSci, David Connor, BMedSci(Hons), PhD, Desiree Robson, RN, Peter S. Macdonald, MBBS, FRACP, MD, PhD, Christopher S. Hayward, MD, FRACP
Publikováno v:
JHLT Open, Vol 6, Iss , Pp 100133- (2024)
Bleeding complications are a bane of continuous flow left ventricular assist devices (cfLVAD); gastrointestinal bleeding (GIB) from arteriovenous malformation (AVM) predominating. We hypothesized that shear stress disrupts vascular endothelium alteri
Externí odkaz:
https://doaj.org/article/ccfcaaed3a6e4364b1119944b6badeb3
Autor:
Weiyu Chen, Sergey Tumanov, Daniel J. Fazakerley, James Cantley, David E. James, Louise L. Dunn, Taqi Shaik, Cacang Suarna, Roland Stocker
Publikováno v:
Redox Biology, Vol 47, Iss , Pp 102152- (2021)
Background & aims: Plasma concentrations of bilirubin, a product of heme catabolism formed by biliverdin reductase A (BVRA), inversely associate with the risk of metabolic diseases including hepatic steatosis and diabetes mellitus in humans. Bilirubi
Externí odkaz:
https://doaj.org/article/41af8d9bb78949eebc861578f2f815f1
Autor:
Weiyu Chen, Sergey Tumanov, Christopher P. Stanley, Stephanie M.Y. Kong, James Nadel, Niv Vigder, Darren L. Newington, Xiao Suo Wang, Louise L. Dunn, Roland Stocker
Publikováno v:
Circulation Research. 132:812-827
Background: The rupture of atherosclerotic plaque contributes significantly to cardiovascular disease. Plasma concentrations of bilirubin—a byproduct of heme catabolism—inversely associate with risk of cardiovascular disease, although the link be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4087cacf2db7079142f1d78989963372
https://doi.org/10.1161/circresaha.122.322418
https://doi.org/10.1161/circresaha.122.322418
Autor:
Yuen Ting Lam, Richard P. Tan, Praveesuda Michael, Nianji Yang, Louise L. Dunn, John P. Cooke, David S. Celermajer, Steven G. Wise, Martin K.C. Ng
Publikováno v:
Microvascular research. 143
Endothelial dysfunction, hallmarked by an imbalance between vasoconstriction and vasorelaxation, is associated with diabetes. Thioredoxin Interacting protein (TXNIP), controlled by an exquisitely glucose sensitive gene, is increasingly recognized for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b0d771468e9d0574bcbc8b21a40cad9
https://pubmed.ncbi.nlm.nih.gov/35644243
https://pubmed.ncbi.nlm.nih.gov/35644243
Autor:
Young Yu, Steven G Wise, Praveesuda L Michael, Daniel V Bax, Gloria S C Yuen, Matti A Hiob, Giselle C Yeo, Elysse C Filipe, Louise L Dunn, Kim H Chan, Hamid Hajian, David S Celermajer, Anthony S Weiss, Martin K C Ng
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0131101 (2015)
The deployment of endovascular implants such as stents in the treatment of cardiovascular disease damages the vascular endothelium, increasing the risk of thrombosis and promoting neointimal hyperplasia. The rapid restoration of a functional endothel
Externí odkaz:
https://doaj.org/article/c94a0facf2934d7e91a094afe368a125
Autor:
Kim H Chan, Philippa J L Simpson, Andy S Yong, Louise L Dunn, Chirapan Chawantanpipat, Chijen Hsu, Young Yu, Anthony C Keech, David S Celermajer, Martin K C Ng
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e93980 (2014)
BACKGROUND: Endothelial progenitor cells (EPCs) are implicated in protection against vascular disease. However, studies using angiography alone have reported conflicting results when relating EPCs to epicardial coronary artery disease (CAD) severity.
Externí odkaz:
https://doaj.org/article/f68aff4e87da4a0f9176a02b3aa5c90e
Autor:
James Cantley, Robyn G. Midwinter, Kim H. Chan, Weiyu Chen, Anita Ayer, Ghassan J. Maghzal, Stephanie M.Y. Kong, Louise L. Dunn, Martin K.C. Ng, Roland Stocker, Sergey Tumanov
Publikováno v:
Arteriosclerosis, thrombosis, and vascular biology. 41(1)
Objective: Hmox1 (heme oxygenase-1) is a stress-induced enzyme that catalyzes the degradation of heme to carbon monoxide, iron, and biliverdin. Induction of Hmox1 and its products protect against cardiovascular disease, including ischemic injury. Hmo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00ef5b0a5ed20e9680db4f96b4c82120
https://pubmed.ncbi.nlm.nih.gov/33207934
https://pubmed.ncbi.nlm.nih.gov/33207934
Autor:
Kim H. Chan, Louise L. Dunn, Andy S.C. Yong, Philippa J. L. Simpson, Laura Lecce, Martin K.C. Ng, Yuen Ting Lam, Daniel P Sieveking, C. Hsu, David S. Celermajer, Young Yu, Jun Yuan, Steven G. Wise, Renee Chow
Publikováno v:
Endocrinology. 161(5)
Endothelial progenitor cells (EPCs) play a key role in neovascularization and have been linked to improved cardiovascular outcomes. Although there is a well-established inverse relationship between androgen levels and cardiovascular mortality in men,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ac1a2bddfc46236ef8dd1c72cd1494c
https://pubmed.ncbi.nlm.nih.gov/32157309
https://pubmed.ncbi.nlm.nih.gov/32157309
Publikováno v:
Free Radical Biology and Medicine. 115:156-165
Bilirubin, a byproduct of heme catabolism, has been shown to be an effective lipid-soluble antioxidant in vitro. Bilirubin is able to inhibit free radical chain reactions and protects against oxidant-induced damage in vitro and ex vivo. However, dire
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c456ec5d904d3aba286ce92783add73
https://doi.org/10.1016/j.freeradbiomed.2017.11.020
https://doi.org/10.1016/j.freeradbiomed.2017.11.020
Autor:
Beat H. Walpoth, Jean-Christophe Tille, Sarra de Valence, Marijana Miljkovic-Licina, Roland Stocker, Philippe Hammel, Louise L. Dunn, Beat A. Imhof
Publikováno v:
Wound Repair and Regeneration. 24:1030-1035
Three-dimensional biomimetic scaffolds resembling the native extracellular matrix (ECM) are widely used in tissue engineering, however they often lack optimal bioactive cues needed for acceleration of cell proliferation, neovascularization, and tissu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f0872d3ea88aa1cbc3d020886c1ac57
https://doi.org/10.1111/wrr.12485
https://doi.org/10.1111/wrr.12485