Phase I and Pharmacologic Study of 17-(Allylamino)-17-Demethoxygeldanamycin in Adult Patients With Solid Tumors

Autor: Rebecca R. Thomas, J. Michael Hamilton, Elizabeth B. Agnew, Jean L. Grem, Geraldine Morrison, Chris H. Takimoto, Frank Grollman, Louise Grochow, Eva Szabo, Xiao Du Guo, Len Neckers, Richard H. Wilson

Publikováno v: Journal of Clinical Oncology. 23:1885-1893

Purpose To determine the clinical toxicities of 17-(allylamino)-17-demethoxygeldanamycin (17-AAG) given as a 1-hour infusion daily for 5 days every 3 weeks. Patients and Methods Nineteen patients received 17-AAG over six dose levels (10 to 56 mg/m2)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08ec9755e546fd5b3041848629ccbde9
https://doi.org/10.1200/jco.2005.12.085

Contributors

Autor: James L. Abbruzzese, Martin D. Abeloff, Ghassan K. Abou-Alfa, Janet L. Abrahm, Jeffery S. Abrams, Geza Acs, Joseph Aisner, Seena C. Aisner, Rhoda M. Alani, Steven R. Alberts, Richard F. Ambinder, Leslie A. Andritsos, Frederick R. Appelbaum, Sachin Apte, James O. Armitage, Deborah Armstrong, Mamad M. Bagheri, Charles M. Balch, Lodovico Balducci, Claudia Beghé, Robert Benjamin, Charles L. Bennett, Ross Stuart Berkowitz, Donna Bernstein, Michael R. Bishop, William J. Blot, Leslie Blumgart, Guido T. Bommer, Michael J. Borowitz, Julie R. Brahmer, Viven H.C. Bramwell, Malcom V. Brock, Ali Bydon, Mitchell S. Cairo, Dario Campana, David P. Carbone, H. Ballentine Carter, Manpreet K. Chadha, Daniel W. Chan, Alfred E. Chang, Nai-Kong V. Cheung, Michaele Christian, Michael F. Clarke, Anthony Cmelak, Peter F. Coccia, Alfred M. Cohen, Robert E. Coleman, Carolyn Compton, Linda D. Cooley, Jorge Cortes, Sara A. Courtneidge, Kenneth H. Cowan, Daniel J. Culkin, Josep Dalmau, Giulio J. D'Angio, Laura Dawson, Steven R. Deitcher, Ronald P. DeMatteo, Philip A. DeSimone, Theodore L. DeWeese, Subba R. Digumarthy, Angela Dispenzieri, Jeffrey S. Dome, John H. Donohue, James H. Doroshow, Jeffery A. Drebin, Dan G. Duda, Austin Duffy, Linda R. Duska, Mario A. Eisenberger, Rebecca L. Elstrom, Janine T. Erler, Michael S. Ewer, Eric R. Fearon, Leslie A. Fecher, Alessandro Fichera, Alexandra H. Filipovich, Karen A. Fitzner, Robert L. Foote, James M. Foran, Arlene A. Forastiere, James M. Ford, Alison G. Freifeld, Carl E. Freter, Arlan F. Fuller, Emma E. Furth, Michael C. Garofalo, Mark C. Gebhardt, N. Lynn Gerber, Manish Gharia, Amato J. Giaccia, Mark R. Gilbert, John Glaspy, Katrina Y. Glover, Ziya L. Gokaslan, Nicola Gökbuget, Donald Peter Goldstein, Adriana Gonzalez, Anne Kathryn Goodman, Ellen Gordon, Daniel M. Green, Michael R. Grever, Andrew Grigg, Louise Grochow, Thomas G. Gross, Stuart A. Grossman, Leonard L. Gunderson, Juliet Gunkel, Martin Gutierrez, Thomas M. Habermann, Barrett G. Haik, John D. Hainsworth, Dennis Hallahan, Nader N. Hanna, Eleanor E.R. Harris, Ernie Hawk, Nancy H. Heideman, Richard L. Heideman, Lee J. Helman, Jessica Hochberg, Dieter Hoelzer, Ingunn Holen, Sandra J. Horning, Kim Huang, Peter B. Illei, Elaine S. Jaffe, Sanjay B. Jagannath, Rakesh K. Jain, William Jarnagin, Anuja Jhingran, David H. Johnson, Heather Jones, Kevin D. Judy, Rosalyn A. Juergens, Jeffrey A. Kant, Hagop Kantarjian, Zeynel A. Karcioglu, Danielle M. Karyadi, Norbert Kased, Michael B. Kastan, Daniel R. Kaul, John Kawaoka, Margaret Kemeny, Nancy Kemeny, Thomas W. Kensler, Lawrence R. Kleinberg, Boris Kobrinsky, Jeanne Kowalski, Shivaani Kummar, Geeta Lal, Paul F. Lambert, Julie R. Lange, Janessa Laskin, Fred Lee, Susanna I. Lee, Jacqueline Lees, Renato Lenzi, Caryn Lerman, Allan Lipton, Charles L. Loprinzi, Gerard Lozanski, Robert Lustig, Mitchell Machtay, Amit Maity, Uzma Malik, C. Scott Manatt, John C. Mansour, Pierre P. Massion, R. Samuel Mayer, Beryl McCormick, Charles J. McDonald, Ross McDougall, W. Gillies McKenna, Steven Meranze, James M. Metz, Frank L. Meyskens, Fabrizio Michelassi, Radha Mikkilineni, Victoria Mock, Mohammed Mohiuddin, James Montie, A. Ross Morton, Anthony J. Murgo, James R. Neff, William G. Nelson, Suzanne Nesbit, John E. Niederhuber, Tracey O'Connor, Thomas O'Dorisio, Kenneth Offit, Mihaela Onciu, Eileen M. O'Reilly, Elaine A. Ostrander, Brian O'Sullivan, Drew M. Pardoll, Catherine K. Park, Freda Patterson, Steven Z. Pavletic, Michael C. Perry, LoAnn C. Peterson, Peter C. Phillips, Steven Piantadosi, Robert Pili, Peter W.T. Pisters, Mark R. Pittelkow, John P. Plastaras, Elizabeth A. Platz, Julian Pribaz, Amy A. Pruitt, Ching-Hon Pui, Joe Bill Putnam, Harry Quon, Martin N. Raber, S. Vincent Rajkumar, William F. Regine, Mark Ritter, John Robert Roberts, Leslie Robinson-Bostom, Ronald Rodriguez, Carlos Rodriguez-Galindo, Myrna Rosenfeld, Nadia Rosenthal, James L. Rubenstein, Brian P. Rubin, Reena Rupani, Valerie W. Rusch, Anthony H. Russell, Charles J. Ryan, Vergilio Sacchini, Alan B. Sandler, Howard Sandler, John T. Sandlund, Victor M. Santana, Robert A. Schnoll, Daniel M. Sciubba, Michael V. Seiden, Mikkael A. Sekeres, William H. Sharfman, Ricky A. Sharma, Kostandinos Sideras, Kenneth Silver, Eric J. Small, David C. Smith, Penny K. Sneed, Stephen N. Snow, Lori J. Sokoll, Mika A. Sovak, James L. Speyer, Alex I. Spira, Dempsey Springfield, Sheri L. Spunt, Daniel Stewart, Paul T. Strickland, Bill Sugden, Siobhan Sutcliffe, Weijing Sun, Martin S. Tallman, James E. Talmadge, Ayalew Tefferi, Peter Thom, Craig B. Thompson, Michael J. Tisdale, Kensei Tobinai, Joseph E. Tomaszewski, Suzanne L. Topalian, Frank M. Torti, Donald L. Trump, Katherine A. Vallis, Gauri R. Varadhachary, Sreenivas Vemulapalli, Kala Visvanathan, Nina D. Wagner-Johnston, Richard L. Wahl, Toshiki Watanabe, Barbara L. Weber, Sharon Weber, Ronald J. Weigel, Irving L. Weissman, William Westra, Kathleen S. Wilson, Wyndham H. Wilson, Antonio C. Wolff, Sandra L. Wong, Gary S. Wood, Lance S. Wyatt, Anaadriana Zakarija, Tal Z. Zaks, Jason A. Zell

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5a104de535fc90b923ea3fa0adf72e02
https://doi.org/10.1016/b978-0-443-06694-8.50003-8

CHEMOTHERAPY FOR HIV-ASSOCIATED NON-HODGKIN LYMPHOMA (HIV-NHL) IN COMBINATION WITH HIGHLY ACTIVE ANTIRETROVIRAL THERAPY (HAART) IS NOT ASSOCIATED WITH EXCESSIVE TOXICITY

Autor: David T. Scadden, R. F. Ambinder, Lee Ratner, Lawrence D. Kaplan, Alexandra M. Levine, Charles Flexner, Louise Grochow, David T. Redden, David J. Straus, B. Tan, Fayez Hamzeh, William J. Harrington

Publikováno v: JAIDS: Journal of Acquired Immune Deficiency Syndromes. 21:A32

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c9b94023763eafb4234d343a47ddb162
https://doi.org/10.1097/00126334-199905010-00112

Class Notes.

Publikováno v: MIT Technology Review. Jan/Feb2014, Vol. 117 Issue 1, Special section p23-61. 39p.

Targeting epidermal growth factor receptor -- are we missing the mark?

Autor: Dancey JE (AUTHOR), Freidlin B (AUTHOR)

Publikováno v: Lancet. 7/5/2003, Vol. 362 Issue 9377, p62-64. 3p.