Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Louise Gorham"'
Autor:
Priyank A. Shenoy, Andy Kuo, Nemat Khan, Louise Gorham, Janet R. Nicholson, Laura Corradini, Irina Vetter, Maree T. Smith
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
In the majority of patients with breast cancer in the advanced stages, skeletal metastases are common, which may cause excruciating pain. Currently available drug treatments for relief of breast cancer-induced bone pain (BCIBP) include non-steroidal
Externí odkaz:
https://doaj.org/article/eaa4d15ce2c74745bd145a32e74f7e41
Autor:
Stefan G. Lechner, Hagen Wende, Vijayan Gangadharan, Vincenzo Prato, Carmen Birchmeier, Paul A. Heppenstall, Francisco J. Taberner, Louise Gorham, Rahul Dhandapani, Alice Arcourt
Publikováno v:
Neuron. 93:179-193
Painful mechanical stimuli activate multiple peripheral sensory afferent subtypes simultaneously, including nociceptors and low-threshold mechanoreceptors (LTMRs). Using an optogenetic approach, we demonstrate that LTMRs do not solely serve as touch
Publikováno v:
Neuroscience Letters. 573:35-39
Somatostatin (sst) is a cyclic neuropeptide known to have inhibitory roles in the central nervous system. It exerts its biological effects via the activation of the 5 sst receptor subtypes, which belong to the family of G-protein coupled receptors (G
Publikováno v:
European journal of pharmacology. 746
Somatostatin (SST) is a peptide hormone that regulates the endocrine system and affects neurotransmission via interaction with G protein-coupled SST receptors and inhibition of the release of different hormones. The aim of this study was to investiga
Publikováno v:
European journal of pharmacology. 736
Somatostatin has a wide biological profile resulting from its actions on the five receptor subtypes (sst1-5). Recently somatostatin was shown to exert analgesic effects via activation of the sst4 receptor. Although the analgesia in pain models is est