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A critical role for heme synthesis and succinate in the regulation of pluripotent states transitions
Autor:
Damien Detraux, Marino Caruso, Louise Feller, Maude Fransolet, Sébastien Meurant, Julie Mathieu, Thierry Arnould, Patricia Renard
Publikováno v:
eLife, Vol 12 (2023)
Using embryonic stem cells (ESCs) in regenerative medicine or in disease modeling requires a complete understanding of these cells. Two main distinct developmental states of ESCs have been stabilized in vitro, a naïve pre-implantation stage and a pr
Externí odkaz:
https://doaj.org/article/5371a2011e5f40b5bb90b4a3f61502c9
A critical role for heme synthesis and succinate in the regulation of pluripotent states transitions
Autor:
Damien Detraux, Marino Caruso, Louise Feller, Maude Fransolet, Sébastien Meurant, Julie Mathieu, Thierry Arnould, Patricia Renard
Using embryonic stem cells (ESCs) in regenerative medicine or in disease modeling requires a complete understanding of these cells. Two main distinct developmental states of ESCs have been stabilized in vitro, a naïve pre-implantation stage and a pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c0e9ec2934b90834fa8853d3f68dbef
https://doi.org/10.1101/2022.03.10.483773
https://doi.org/10.1101/2022.03.10.483773