Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Louise Falk"'
Autor:
Sarah Holmes Watkins, Karen Ho, Christian Testa, Louise Falk, Patrice Soule, Linda V. Nguyen, Sophie FitzGibbon, Catherine Slack, Jarvis T. Chen, George Davey Smith, Immaculata De Vivo, Andrew J. Simpkin, Kate Tilling, Pamela D. Waterman, Nancy Krieger, Matthew Suderman, Caroline Relton
Publikováno v:
Epigenetics, Vol 17, Iss 13, Pp 2366-2376 (2022)
DNA methylation (DNAm) is commonly assayed using the Illumina Infinium MethylationEPIC BeadChip, but there is currently little published evidence to define the lower limits of the amount of DNA that can be used whilst preserving data quality. Such ev
Externí odkaz:
https://doaj.org/article/eb96d333ade340c9b3ea5ba8f715f287
Autor:
Jie Zheng, Eleanor Wheeler, Maik Pietzner, Till F.M. Andlauer, Michelle S. Yau, April E. Hartley, Ben Michael Brumpton, Humaira Rasheed, John P Kemp, Monika Frysz, Jamie Robinson, Sjur Reppe, Vid Prijatelj, Kaare M. Gautvik, Louise Falk, Winfried Maerz, Ingrid Gergei, Patricia A Peyser, Maryam Kavousi, Paul S. de Vries, Clint L. Miller, Maxime Bos, Sander W. van der Laan, Rajeev Malhotra, Markus Herrmann, Hubert Scharnagl, Marcus Kleber, George Dedoussis, Eleftheria Zeggini, Maria Nethander, Claes Ohlsson, Mattias Lorentzon, Nick Wareham, Claudia Langenberg, Michael V. Holmes, George Davey Smith, Jonathan H. Tobias
Publikováno v:
Arthritis & Rheumatology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cfa5ce785e959e6631bbd0da3b1910f2
https://doi.org/10.1002/art.42538
https://doi.org/10.1002/art.42538
Autor:
Laura J, Corbin, Stephen J, White, Amy E, Taylor, Christopher M, Williams, Kurt, Taylor, Marion T, van den Bosch, Jack E, Teasdale, Matthew, Jones, Mark, Bond, Matthew T, Harper, Louise, Falk, Alix, Groom, Georgina G J, Hazell, Lavinia, Paternoster, Marcus R, Munafò, Børge G, Nordestgaard, Anne, Tybjærg-Hansen, Stig E, Bojesen, Caroline, Relton, Josine L, Min, George, Davey Smith, Andrew D, Mumford, Alastair W, Poole, Nicholas J, Timpson
Publikováno v:
Circulation research. 130(3)
DNA hypomethylation at theWe conducted multiple independent experiments to assess whether DNA hypomethylation atObservationally, DNA methylation atSmoking-induced epigenetic DNA hypomethylation at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a0e2e1314b8e9d9393c96726078206ff
https://pubmed.ncbi.nlm.nih.gov/35012325
https://pubmed.ncbi.nlm.nih.gov/35012325
Autor:
Laura J. Corbin, Stephen J. White, Amy E. Taylor, Christopher M. Williams, Kurt Taylor, Marion T. van den Bosch, Jack E. Teasdale, Matthew Jones, Mark Bond, Matthew T. Harper, Louise Falk, Alix Groom, Georgina G.J. Hazell, Lavinia Paternoster, Marcus R. Munafò, Børge G. Nordestgaard, Anne Tybjærg-Hansen, Stig E. Bojesen, Caroline Relton, Josine L. Min, George Davey Smith, Andrew D. Mumford, Alastair W. Poole, Nicholas J. Timpson
Publikováno v:
Corbin, L J, White, S J, Taylor, A E, Williams, C M, Taylor, K, Van Den Bosch, M T, Teasdale, J E, Jones, M, Bond, M, Harper, M T, Falk, L, Groom, A, Hazell, G G J, Paternoster, L, Munafò, M R, Nordestgaard, B G, Tybjærg-Hansen, A, Bojesen, S E, Relton, C, Min, J L, Davey Smith, G, Mumford, A D, Poole, A W & Timpson, N J 2022, ' Epigenetic Regulation of F2RL3 Associates with Myocardial Infarction and Platelet Function ', Circulation Research, vol. 130, no. 3, pp. 384-400 . https://doi.org/10.1161/CIRCRESAHA.121.318836
Corbin, L J, White, S J, Taylor, A E, Williams, C M, Taylor, K, Van Den Bosch, M T J, Teasdale, J E, Jones, M L, Bond, M, Harper, M T, Falk, L, Groom, A, Hazell, G G J, Paternoster, L, Munafo, M R, Nordestgaard, B G, Tybjaerg-Hansen, A, Bojesen, S E, Relton, C L, Min, J L, Davey Smith, G, Mumford, A D, Poole, A W & Timpson, N J 2022, ' Epigenetic regulation of F2RL3 associates with myocardial infarction and platelet function ', Circulation Research, vol. 130, no. 3, pp. 384-400 . https://doi.org/10.1161/CIRCRESAHA.121.318836
Corbin, L J, White, S J, Taylor, A E, Williams, C M, Taylor, K, Van Den Bosch, M T J, Teasdale, J E, Jones, M L, Bond, M, Harper, M T, Falk, L, Groom, A, Hazell, G G J, Paternoster, L, Munafo, M R, Nordestgaard, B G, Tybjaerg-Hansen, A, Bojesen, S E, Relton, C L, Min, J L, Davey Smith, G, Mumford, A D, Poole, A W & Timpson, N J 2022, ' Epigenetic regulation of F2RL3 associates with myocardial infarction and platelet function ', Circulation Research, vol. 130, no. 3, pp. 384-400 . https://doi.org/10.1161/CIRCRESAHA.121.318836
Background: DNA hypomethylation at the F2RL3 (F2R like thrombin or trypsin receptor 3) locus has been associated with both smoking and atherosclerotic cardiovascular disease; whether these smoking-related associations form a pathway to disease is unk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4473fb21bcf65ec3e1e8f70d3954772e
https://curis.ku.dk/portal/da/publications/epigenetic-regulation-of-f2rl3-associates-with-myocardial-infarction-and-platelet-function(9edd7f9a-ae4c-4c1a-8e3e-eda1d3fad1da).html
https://curis.ku.dk/portal/da/publications/epigenetic-regulation-of-f2rl3-associates-with-myocardial-infarction-and-platelet-function(9edd7f9a-ae4c-4c1a-8e3e-eda1d3fad1da).html
Autor:
Sarah Holmes Watkins, Karen Ho, Christian Testa, Louise Falk, Patrice Soule, Linda V. Nguyen, Sophie FitzGibbon, Catherine Slack, Jarvis T. Chen, George Davey Smith, Immaculata De Vivo, Andrew J. Simpkin, Kate Tilling, Pamela D. Waterman, Nancy Krieger, Matthew Suderman, Caroline Relton
Publikováno v:
Watkins, S H, Ho, K M, Testa, C, Falk, L, Soule, P, Nguyen, L V, FitzGibbon, S J, Slack, C J, Chen, J, Davey Smith, G, De Vivo, I, Simpkin, A J, Tilling, K M, Waterman, P, Krieger, N, Suderman, M J & Relton, C L 2022, ' The impact of low input DNA on the reliability of DNA methylation as measured by the Illumina Infinium MethylationEPIC BeadChip ', Epigenetics, vol. 17, no. 13, pp. 2366-2376 . https://doi.org/10.1080/15592294.2022.2123898
BackgroundDNA methylation (DNAm) is commonly assayed using the Illumina Infinium MethylationEPIC BeadChip, but there is currently little published evidence to define the lower limits of the amount of DNA that can be used whilst preserving data qualit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ef5983540bfed41d301e3247060c438
https://doi.org/10.1101/2021.12.22.473840
https://doi.org/10.1101/2021.12.22.473840
Autor:
Nazanin Mirza-Schreiber, Louise Falk, George Davey Smith, Till F. M. Andlauer, Winfried März, Bertram Müller-Myhsok, Ingrid Gergei, Jonathan H Tobias, Vincent Brandenburg, Daniel Richard, Bernhard K. Krämer, Jakob Voelkl, Jie Zheng, Claes Ohlsson, Sofia Movérare-Skrtic
Publikováno v:
HUMAN MOLECULAR GENETICS
Gergei, I, Zheng, J, Andlauer, T F M, Brandenburg, V, Mirza-Schreiber, N, Müller-Myhsok, B, Krämer, B K, Richard, D, Falk, L, Moverare-Skrtic, S, Ohlsson, C, Davey Smith, G, März, W, Voelkl, J & Tobias, J H 2021, ' GWAS META-analysis followed by MENDELIAN randomisation revealed potential control mechanisms for circulating α-klotho levels ', Human Molecular Genetics . https://doi.org/10.1093/hmg/ddab263
Gergei, I, Zheng, J, Andlauer, T F M, Brandenburg, V, Mirza-Schreiber, N, Müller-Myhsok, B, Krämer, B K, Richard, D, Falk, L, Moverare-Skrtic, S, Ohlsson, C, Davey Smith, G, März, W, Voelkl, J & Tobias, J H 2021, ' GWAS META-analysis followed by MENDELIAN randomisation revealed potential control mechanisms for circulating α-klotho levels ', Human Molecular Genetics . https://doi.org/10.1093/hmg/ddab263
The protein α-Klotho acts as transmembrane co-receptor for fibroblast growth factor 23 (FGF23) and is a key regulator of phosphate homeostasis. However, α-Klotho also exists in a circulating form, with pleiotropic, but incompletely understood funct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e4993b66ba15d476673fcfd376c3673
https://pubmed.ncbi.nlm.nih.gov/34542150
https://pubmed.ncbi.nlm.nih.gov/34542150
Autor:
Winfried Maerz, Kaare M. Gautvik, Denis Baird, Vincent Brandenburg, Elin Grundberg, Mattias Lorentzon, George Dedoussis, Alix Groom, Enisa Shevroja, Carolina Medina-Gomez, Arthur Gilly, Sjur Reppe, Sofia Movérare-Skrtic, Eleftheria Zeggini, Ingrid Gergei, Karin H Nilsson, Christoph Wanner, Benjamin Elsworth, Maria Nethander, Jonathan H Tobias, Ulf H. Lerner, Petra Henning, Louise Falk, Terence D. Capellini, Young-Chan Park, Marcus E. Kleber, Claes Ohlsson, Jie Zheng, Christiane Drechsler, George Davey Smith
Publikováno v:
J. Bone Min. Res. 34, 1824-1836 (2019)
Zheng, J, Maerz, W, Gergei, I, Kleber, M, Drechsler, C, Wanner, C, Brandenburg, V, Reppe, S, Gautvik, K M, Medina-Gomez, C, Shevroja, E, Gilly, A, Park, Y-C, Dedoussis, G V, Zeggini, E, Lorentzon, M, Henning, P, Lerner, U H, Nilsson, K, Moverare-Skrtic, S, Baird, D A, Elsworth, B L, Falk, L, Groom, A, Capellini, T D, Grundberg, E, Nethander, M, Ohlsson, C, Davey Smith, G & Tobias, J H 2019, ' Mendelian Randomization analysis reveals a causal influence of circulating sclerostin levels on bone mineral density and fractures ', Journal of Bone and Mineral Research . https://doi.org/10.1002/jbmr.3803
Journal of Bone and Mineral Research
Zheng, J, Maerz, W, Gergei, I, Kleber, M, Drechsler, C, Wanner, C, Brandenburg, V, Reppe, S, Gautvik, K M, Medina-Gomez, C, Shevroja, E, Gilly, A, Park, Y-C, Dedoussis, G V, Zeggini, E, Lorentzon, M, Henning, P, Lerner, U H, Nilsson, K, Moverare-Skrtic, S, Baird, D A, Elsworth, B L, Falk, L, Groom, A, Capellini, T D, Grundberg, E, Nethander, M, Ohlsson, C, Davey Smith, G & Tobias, J H 2019, ' Mendelian Randomization analysis reveals a causal influence of circulating sclerostin levels on bone mineral density and fractures ', Journal of Bone and Mineral Research . https://doi.org/10.1002/jbmr.3803
Journal of Bone and Mineral Research
In bone, sclerostin is mainly osteocyte-derived and plays an important local role in adaptive responses to mechanical loading. Whether circulating levels of sclerostin also play a functional role is currently unclear, which we aimed to examine by two
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::821e288ab7566c7b196b3a0f1ac7c07d
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=56270
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=56270
Autor:
Alastair W. Poole, Nicholas J. Timpson, Kurt Taylor, Marion T.J. van den Bosch, Andrew D Mumford, Børge G. Nordestgaard, Amy E Taylor, Alix Groom, Christopher Williams, Lavinia Paternoster, Stig E. Bojesen, Jack E. Teasdale, Stephen J. White, Matthew Jones, Georgina G J Hazell, Anne Tybjærg-Hansen, Louise Falk, Laura J Corbin, Marcus R. Munafò, Caroline L Relton, Josine L. Min, George Davey Smith, Matthew T. Harper, Mark Bond
Protease-activated receptor 4 (PAR4) is a potent thrombin receptor. Epigenetic control of theF2RL3locus (which encodes for PAR4) via DNA methylation is associated with both smoking and cardiovascular disease. We examined the association between DNA h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92e2cbf6dd5c1e49b88c3df8aab21f87
https://doi.org/10.1101/473728
https://doi.org/10.1101/473728
Autor:
Tranberg, Louise Falk
This thesis will address decision-making processes in welfare change programs in Denmark in the twenty-first century. The main focus is how decisions are made in welfare programs that are popular in the public. In relation to change these highly popu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______278::4ccb4c22f5ff699943f27dd7b7b16b01
https://rucforsk.ruc.dk/ws/files/57701190/Speciale_Louise_Falk_Tranberg.pdf
https://rucforsk.ruc.dk/ws/files/57701190/Speciale_Louise_Falk_Tranberg.pdf