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pro vyhledávání: '"Louise F. Dow"'
Autor:
Angelica V. Carmona, Shirisha Jonnalagadda, Alfie M. Case, Krishnaiah Maddeboina, Sravan K. Jonnalagadda, Louise F. Dow, Ling Duan, Trevor M. Penning, Paul C. Trippier
Publikováno v:
Communications Chemistry, Vol 7, Iss 1, Pp 1-10 (2024)
Abstract Aldo-keto reductase 1C3 (AKR1C3) is a protein upregulated in prostate cancer, hematological malignancies, and other cancers where it contributes to proliferation and chemotherapeutic resistance. Androgen receptor splice variant 7 (ARv7) is t
Externí odkaz:
https://doaj.org/article/e4ce2a22fe6441639dc3ca4d9f796b99
Autor:
Ahmed Morsy, Krishnaiah Maddeboina, Ju Gao, Hezhen Wang, Juan Valdez, Louise F. Dow, Xinglong Wang, Paul C. Trippier
Publikováno v:
ACS Chemical Neuroscience. 13:2176-2190
Alzheimer's disease (AD) is the most common dementia affecting one in nine people over 65. Only a handful of small-molecule drugs and the anti-β amyloid (Aβ) antibody aducanumab are approved to treat AD. However, they only serve to reduce symptoms