Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Louise E. Olofsson"'
Autor:
Kristina S. Fluitman, Mark Davids, Louise E. Olofsson, Madelief Wijdeveld, Valentina Tremaroli, Bart J.F. Keijser, Marjolein Visser, Fredrik Bäckhed, Max Nieuwdorp, Richard G. IJzerman
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 13, Iss 4, Pp 2188-2201 (2022)
Abstract Background Older adults are particularly prone to the development of poor appetite and undernutrition. Possibly, this is partly due to the aged gut microbiota. We aimed to evaluate the gut microbiota in relation to both poor appetite and und
Externí odkaz:
https://doaj.org/article/5562dcb6a38148b1abc23cb1258ca2ae
Autor:
Dimitra Lappa, Abraham S. Meijnikman, Kimberly A. Krautkramer, Lisa M. Olsson, Ömrüm Aydin, Anne-Sophie Van Rijswijk, Yair I. Z. Acherman, Maurits L. De Brauw, Valentina Tremaroli, Louise E. Olofsson, Annika Lundqvist, Siv A. Hjorth, Boyang Ji, Victor E. A. Gerdes, Albert K. Groen, Thue W. Schwartz, Max Nieuwdorp, Fredrik Bäckhed, Jens Nielsen
Publikováno v:
PLoS ONE, Vol 18, Iss 3 (2023)
Weight loss through bariatric surgery is efficient for treatment or prevention of obesity related diseases such as type 2 diabetes and cardiovascular disease. Long term weight loss response does, however, vary among patients undergoing surgery. Thus,
Externí odkaz:
https://doaj.org/article/ff98972c69364e71830211bcfa198324
Autor:
Abraham S. Meijnikman, Dimitra Lappa, Hilde Herrema, Omrum Aydin, Kimberly A. Krautkramer, Valentina Tremaroli, Louise E. Olofsson, Annika Lundqvist, Sjoerd Bruin, Yair Acherman, Joanne Verheij, Siv Hjorth, Victor E.A. Gerdes, Thue W. Schwartz, Albert K. Groen, Fredrik Bäckhed, Jens Nielsen, Max Nieuwdorp
Publikováno v:
iScience, Vol 25, Iss 8, Pp 104828- (2022)
Summary: Non-alcoholic fatty liver disease (NAFLD) is now the most frequent global chronic liver disease. Individuals with NAFLD exhibited an increased risk of all-cause mortality driven by extrahepatic cancers and liver and cardiovascular disease. O
Externí odkaz:
https://doaj.org/article/ed8d0c4c87de4b7a9a28489d9121d7d3
Autor:
Abraham S. Meijnikman, Casper C. van Olden, Ömrüm Aydin, Hilde Herrema, Dorota Kaminska, Dimitra Lappa, Ville Männistö, Valentina Tremaroli, Louise E. Olofsson, Maurits de Brauw, Arnold van de Laar, Joanne Verheij, Victor E.A. Gerdes, Thue W. Schwartz, Jens Nielsen, Fredrik Bäckhed, Päivi Pajukanta, Jussi Pihlajamäki, Tamar Tchkonia, James L. Kirkland, Folkert Kuipers, Max Nieuwdorp, Albert K. Groen
Publikováno v:
Diabetes, 71(9), 1929-1936. American Diabetes Association Inc.
Meijnikman, A S, van Olden, C C, Aydin, Ö, Herrema, H, Kaminska, D, Lappa, D, Männistö, V, Tremaroli, V, Olofsson, L E, de Brauw, M, van de Laar, A, Verheij, J, Gerdes, V E A, Schwartz, T W, Nielsen, J, Bäckhed, F, Pajukanta, P I, Pihlajamäki, J, Tchkonia, T, Kirkland, J L, Kuipers, F, Nieuwdorp, M & Groen, A K 2022, ' Hyperinsulinemia Is Highly Associated With Markers of Hepatocytic Senescence in Two Independent Cohorts ', Diabetes, vol. 71, no. 9, pp. 1929-1936 . https://doi.org/10.2337/db21-1076
Diabetes, 71(9), 1929-1936. AMER DIABETES ASSOC
Meijnikman, A S, van Olden, C C, Aydin, Ö, Herrema, H, Kaminska, D, Lappa, D, Männistö, V, Tremaroli, V, Olofsson, L E, de Brauw, M, van de Laar, A, Verheij, J, Gerdes, V E A, Schwartz, T W, Nielsen, J, Bäckhed, F, Pajukanta, P I, Pihlajamäki, J, Tchkonia, T, Kirkland, J L, Kuipers, F, Nieuwdorp, M & Groen, A K 2022, ' Hyperinsulinemia Is Highly Associated With Markers of Hepatocytic Senescence in Two Independent Cohorts ', Diabetes, vol. 71, no. 9, pp. 1929-1936 . https://doi.org/10.2337/db21-1076
Diabetes, 71(9), 1929-1936. AMER DIABETES ASSOC
Cellular senescence is an essentially irreversible growth arrest that occurs in response to various cellular stressors and may contribute to development of type 2 diabetes and Non-Alcoholic Fatty Liver Disease (NAFLD). Here, we investigated whether c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8aad1a63d3c6b6c78d0d700e68ece88c
http://www.scopus.com/inward/record.url?scp=85137008651&partnerID=8YFLogxK
http://www.scopus.com/inward/record.url?scp=85137008651&partnerID=8YFLogxK
Publikováno v:
Molecular Neurobiology. 59:3755-3766
Circumventricular organs (CVOs), including the mediobasal hypothalamus (MBH), have an incomplete blood–brain barrier (BBB). In this study, we determined if the BBB function in the MBH is modulated by the gut microbiota or by the Toll-like receptor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::899db6227cffe832ddef3c0821bb4727
https://doi.org/10.1007/s12035-022-02802-w
https://doi.org/10.1007/s12035-022-02802-w
Autor:
Peishun Li, Boyang Ji, Dimitra Lappa, Abraham S Meijnikman, Lisa M. Olsson, Ömrüm Aydin, Sjoerd C. Bruin, Arnold van de Laar, Valentina Tremaroli, Hao Luo, Jun Geng, Kimberly A. Krautkramer, Annika Lundqvist, Hilde Herrema, Albert K. Groen, Victor E.A. Gerdes, Thue W. Schwartz, Fredrik Bäckhed, Max Nieuwdorp, Louise E. Olofsson, Jens Nielsen
Individuals with prediabetes and type 2 diabetes mellitus (T2DM) have poor ability to adapt to diet-triggered perturbations. We investigated global metabolic responses to a mixed meal test (MMT) in morbidly obese individuals with different diabetic s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::41849c5c30b9c4977a92eb5880d7437c
https://doi.org/10.1101/2022.04.26.489057
https://doi.org/10.1101/2022.04.26.489057
Autor:
Louise E Olofsson, Fredrik Bäckhed
Publikováno v:
Olofsson, L E & Backhed, F 2022, ' The Metabolic Role and Therapeutic Potential of the Microbiome ', Endocrine Reviews, vol. 43, pp. 907-926 . https://doi.org/10.1210/endrev/bnac004
We are host to an assembly of microorganisms that vary in structure and function along the length of the gut and from the lumen to the mucosa. This ecosystem is collectively known as the gut microbiota and significant efforts have been spent during t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d94d5334362cf27098ef88839f95cfc7
https://pubmed.ncbi.nlm.nih.gov/35094076
https://pubmed.ncbi.nlm.nih.gov/35094076
Autor:
N. C. Bosma, Ömrüm Aydin, Louise E. Olofsson, Fredrik Bäckhed, Siv A. Hjorth, N. van Olst, C. C. Van Olden, J. Verheij, Hilde Herrema, M. Nieuwdorp, Jens Nielsen, A. W. van de Laar, Sjoerd C. Bruin, V. E. A. Gerdes, Dimitra Lappa, Mariët Hagedoorn, Abraham S. Meijnikman, Thue W. Schwartz, Albert K. Groen, Annika Lundqvist, L. M. de Brauw, Valentina Tremaroli, Yair I. Z. Acherman, Robbert Sanderman, J. B. Hoozemans, Johanna Eveliina Pyykkö
Publikováno v:
Journal of internal medicine, 289(3), 340-354. Wiley-Blackwell
Journal of Internal Medicine
Van Olden, C C, Van de Laar, A W, Meijnikman, A S, Aydin, O, Van Olst, N, Hoozemans, J B, De Brauw, L M, Bruin, S C, Acherman, Y I Z, Verheij, J, Pyykko, J E, Hagedoorn, M, Sanderman, R, Bosma, N C, Tremaroli, V, Lundqvist, A, Olofsson, L E, Herrema, H, Lappa, D, Hjorth, S, Nielsen, J, Schwartz, T, Groen, A K, Nieuwdorp, M, Backhed, F & Gerdes, V E A 2021, ' A systems biology approach to understand gut microbiota and host metabolism in morbid obesity : design of the BARIA Longitudinal Cohort Study ', Journal of Internal Medicine, vol. 289, no. 3, pp. 340-354 . https://doi.org/10.1111/joim.13157
Journal of Internal Medicine
Van Olden, C C, Van de Laar, A W, Meijnikman, A S, Aydin, O, Van Olst, N, Hoozemans, J B, De Brauw, L M, Bruin, S C, Acherman, Y I Z, Verheij, J, Pyykko, J E, Hagedoorn, M, Sanderman, R, Bosma, N C, Tremaroli, V, Lundqvist, A, Olofsson, L E, Herrema, H, Lappa, D, Hjorth, S, Nielsen, J, Schwartz, T, Groen, A K, Nieuwdorp, M, Backhed, F & Gerdes, V E A 2021, ' A systems biology approach to understand gut microbiota and host metabolism in morbid obesity : design of the BARIA Longitudinal Cohort Study ', Journal of Internal Medicine, vol. 289, no. 3, pp. 340-354 . https://doi.org/10.1111/joim.13157
Introduction Prevalence of obesity and associated diseases, including type 2 diabetes mellitus, dyslipidaemia and non‐alcoholic fatty liver disease (NAFLD), are increasing. Underlying mechanisms, especially in humans, are unclear. Bariatric surgery
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4795836e2149c7d68c1859e15107fad
https://pure.amc.nl/en/publications/a-systems-biology-approach-to-understand-gut-microbiota-and-host-metabolism-in-morbid-obesity-design-of-the-baria-longitudinal-cohort-study(d5aa344b-dc3d-4d7e-b1e2-0d89a5dd9030).html
https://pure.amc.nl/en/publications/a-systems-biology-approach-to-understand-gut-microbiota-and-host-metabolism-in-morbid-obesity-design-of-the-baria-longitudinal-cohort-study(d5aa344b-dc3d-4d7e-b1e2-0d89a5dd9030).html
Autor:
Kiymet Citirikkaya, Fredrik Bäckhed, Audrey Poupeau, Louise E. Olofsson, Christian Garde, Karolina Sulek, Manimozhiyan Arumugam, David Simar, Jonas T. Treebak, Romain Barrès
Publikováno v:
The FASEB Journal
Poupeau, A, Garde, C, Sulek, K, Citirikkaya, K, Treebak, J T, Arumugam, M, Simar, D, Olofsson, L E, Bäckhed, F & Barrès, R 2019, ' Genes controlling the activation of natural killer lymphocytes are epigenetically remodeled in intestinal cells from germ-free mice ', F A S E B Journal, vol. 33, no. 2, pp. 2719-2731 . https://doi.org/10.1096/fj.201800787R
Poupeau, A, Garde, C, Sulek, K, Citirikkaya, K, Treebak, J T, Arumugam, M, Simar, D, Olofsson, L E, Bäckhed, F & Barrès, R 2019, ' Genes controlling the activation of natural killer lymphocytes are epigenetically remodeled in intestinal cells from germ-free mice ', F A S E B Journal, vol. 33, no. 2, pp. 2719-2731 . https://doi.org/10.1096/fj.201800787R
Remodeling of the gut microbiota is implicated in various metabolic and inflammatory diseases of the gastrointestinal tract. We hypothesized that the gut microbiota affects the DNA methylation profile of intestinal epithelial cells (IECs) which could
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dec9e4a3cc1465de3968d39ef04cd75
https://doi.org/10.1096/fj.201800787r
https://doi.org/10.1096/fj.201800787r
Autor:
Louise E. Olofsson, Christina N. Heiss
Publikováno v:
Journal of Innate Immunity. 10:163-171
The gut microbiota has emerged as an environmental factor that modulates the host's energy balance. It increases the host's ability to harvest energy from the digested food, and produces metabolites and microbial products such as short-chain fatty ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cde38eee1f186473c3e6b49e5755a9d
https://doi.org/10.1159/000481519
https://doi.org/10.1159/000481519