Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Louise D. Fraser"'
Autor:
Jo eSpencer, Louise D Fraser
Publikováno v:
Frontiers in Immunology, Vol 3 (2012)
Understanding the cellular and molecular mechanisms that generate the human intestinal IgA response is fundamentally important if effective mucosal vaccination is to be successful and broadly applied. There have been several major advances in this fi
Externí odkaz:
https://doaj.org/article/ae6bae05a01a4382a125bc29ccefae46
Autor:
John Cason, Jo Spencer, Saba Nayar, David D'Cruz, Pamela M. K. Lutalo, Joselli S. Silva, Yuan Zhao, Andrew P. Cope, Louise D. Fraser, Deborah K. Dunn-Walters
Publikováno v:
European Journal of Immunology. 45:2409-2419
The principles of allelic exclusion state that each B cell expresses a single light and heavy chain pair. Here, we show that B cells with both kappa and lambda light chains (Igκ and Igλ) are enriched in some patients with the systemic autoimmune di
Autor:
Deborah K. Dunn-Walters, David D'Cruz, John Cason, Jo Spencer, Romeeza Tahir, LeeMeng Choong, Verena K. Hehle, Yu-Chang Wu, Pamela M. K. Lutalo, Andrew P. Cope, David Glyn Kipling, Louise D. Fraser
Publikováno v:
Molecular immunology. 65(2)
The unique specificity of the B cell receptor is generated by an ordered sequence of gene rearrangement events. Once IGH genes have rearranged, rearrangement at the IGK locus is initiated followed by the IGL locus if functional IGK rearrangement is n
Autor:
Jeremy D. Sanderson, Lee Meng Choong, Lisa Das, Kirstin M. Taylor, Jo Spencer, Paul A. Blair, Anna Vossenkämper, Louise D. Fraser, Theodore J. Sanders, David D'Cruz, Fuju Chang, Niloufar Safinia, Giovanna Lombardi, Andrew J. Stagg, Thomas T. MacDonald
Publikováno v:
The Journal of Experimental Medicine
Transitional 2 B cells home to gut-associated lymphoid tissue and present an activated phenotype in healthy subjects, but gut immune compartments are depleted in SLE.
We have tracked the fate of immature human B cells at a critical stage in thei
We have tracked the fate of immature human B cells at a critical stage in thei