Galectin-3: An early predictive biomarker of modulation of airway remodeling in patients with severe asthma treated with omalizumab for 36 months

Autor: Giorgio Walter Canonica, Claudio Micheletto, Alessandra Chiappori, Roberto W. Dal Negro, Pierluigi Mauri, Louise Benazzi, Anna Maria Riccio, Laura De Ferrari, Dario Di Silvestre, Rossana Rossi

Publikováno v: Clinical and translational allergy 7 (2017). doi:10.1186/s13601-017-0143-1
info:cnr-pdr/source/autori:Riccio, Anna Maria; Mauri, Pierluigi; De Ferrari, Laura; Rossi, Rossana; Di Silvestre, Dario; Benazzi, Louise; Chiappori, Alessandra; Dal Negro, Roberto Walter; Micheletto, Claudio; Canonica, Giorgio Walter/titolo:Galectin-3: an early predictive biomarker of modulation of airway remodeling in patients with severe asthma treated with omalizumab for 36 months/doi:10.1186%2Fs13601-017-0143-1/rivista:Clinical and translational allergy/anno:2017/pagina_da:/pagina_a:/intervallo_pagine:/volume:7
Clinical and Translational Allergy

Background Bronchial asthma is a heterogeneous disease characterized by three cardinal features: chronic inflammation, variable airflow obstruction, and airway hyperresponsiveness. Asthma has traditionally been defined using nonspecific clinical and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d31a7a99a30883eae60fcbc7aa95cc80
http://hdl.handle.net/11567/861308

The Thioredoxin Specificity of Drosophila GPx: A Paradigm for a Peroxiredoxin-like Mechanism of many Glutathione Peroxidases

Autor: Cristiana Bulato, Fulvio Ursini, Antonella Roveri, Katja Becker, Antonella De Palma, Matilde Maiorino, Pierluigi Mauri, Silvio C. E. Tosatto, Valentina Bosello, Louise Benazzi, Stefano Toppo, Leopold Flohé

Publikováno v: Journal of Molecular Biology 365 (2006): 1033–1046. doi:10.1016/j.jmb.2006.10.033
info:cnr-pdr/source/autori:M. Maiorino, F. Ursini, V. Bosello, S. Toppo, S. Tosatto, P.L. Mauri, K. Becker, A. Roveri, C. Bulato, L. Benazzi, A. De Palma and L. Flohé/titolo:The Thioredoxin Specificity Of Drosophila Gpx: A Paradigm For A Peroxiredoxin-Like Mechanism Of Many Glutathione Peroxidases/doi:10.1016%2Fj.jmb.2006.10.033/rivista:Journal of Molecular Biology/anno:2006/pagina_da:1033/pagina_a:1046/intervallo_pagine:1033–1046/volume:365

Some members of the glutathione peroxidase (GPx) family have been reported to accept thioredoxin as reducing substrate. However, the selenocysteine-containing ones oxidise thioredoxin (Trx), if at all, at extremely slow rates. In contrast, the Cys ho

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad95df39ee1f040aaa13b6915839ffef
https://doi.org/10.1016/j.jmb.2006.10.033

Analysis of the Escherichia coli RNA degradosome composition by a proteomic approach

Autor: Maria Elena Regonesi, Paolo Tortora, Gianni Dehò, Marta Del Favero, Pierluigi Mauri, Louise Benazzi, Federica Briani, Fabrizio Basilico

Publikováno v: Biochimie
88 (2006): 151–161. doi:10.1016/j.biochi.2005.07.012
info:cnr-pdr/source/autori:Regonesi ME; Del Favero M; Basilico F; Briani F; Benazzi L; Tortora P; Mauri P; Deho G/titolo:Analysis of the Escherichia coli RNA degradosome composition by a proteomic approach/doi:10.1016%2Fj.biochi.2005.07.012/rivista:Biochimie (Print)/anno:2006/pagina_da:151/pagina_a:161/intervallo_pagine:151–161/volume:88

The RNA degradosome is a bacterial protein machine devoted to RNA degradation and processing. In Escherichia coli it is typically composed of the endoribonuclear RNase E, which also serves as a scaffold for the other components, the exoribonuclease P

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::125bd88072230aede749644e7d2f7890
https://doi.org/10.1016/j.biochi.2005.07.012

Proteomics of bronchial biopsies: Galectin-3 as a predictive biomarker of airway remodelling modulation in omalizumab-treated severe asthma patients

Autor: Laura De Ferrari, Dario Di Silvestre, Anna Maria Riccio, Stephen T. Holgate, Giorgio Walter Canonica, Pierluigi Mauri, Rossana Rossi, Roberto W. Dal Negro, Louise Benazzi

Publikováno v: Immunology letters 162 (2014): 2–10. doi:10.1016/j.imlet.2014.08.010
info:cnr-pdr/source/autori:Mauri, Pierluigi; Riccio, Anna Maria; Rossi, Rossana; Di Silvestre, Dario; Benazzi, Louise; De Ferrari, Laura; Dal Negro, Roberto Walter; Holgate, Stephen T.; Canonica, Giorgio Walter/titolo:Proteomics of bronchial biopsies: Galectin-3 as a predictive biomarker of airway remodelling modulation in omalizumab-treated severe asthma patients/doi:10.1016%2Fj.imlet.2014.08.010/rivista:Immunology letters/anno:2014/pagina_da:2/pagina_a:10/intervallo_pagine:2–10/volume:162

Asthma is a chronic inflammatory disease. Reticular basement membrane (RBM) thickening is considered feature of airway remodelling (AR) particularly in severe asthma (SA). Omalizumab, mAb to IgE is effective in SA and can modulate AR. Herein we descr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd205d5652a543660a73fd165e0c94d3

The circulating level of FABP3 is an indirect biomarker of microRNA-1

Autor: Gloria Saccani Jotti, Carolina Di Somma, Anna Franzone, Pierluigi Mauri, Barbara Gargano, Annamaria Colao, Antonella De Palma, Louise Benazzi, Gianluigi Condorelli, Pierluigi Carullo, Giovanni Esposito, Marie Louise Bang, Dario Di Silvestre, Ludovica F S Grasso, Francesca Varrone, Daniele Catalucci

Publikováno v: Journal of the American College of Cardiology. 61(1)

Objectives This study sought to identify proteins from the cardiomyocyte (CM) secretome that are directly targeted by the muscle-specific microRNA-1 (miR-1), and thus reflect the pathophysiological state of the CM. Background MicroRNAs play critical

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dd2cb71e58f7eb87f05a188eba27d72
https://pubmed.ncbi.nlm.nih.gov/23141496