Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Louise Baker"'
Autor:
Qiao Su, Louise Baker, Samantha Emery, Balu Balan, Brendan Ansell, Swapnil Tichkule, Ivo Mueller, Staffan G. Svärd, Aaron Jex
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 22, Iss , Pp 9-19 (2023)
Benzimidazole-2-carbamates (BZ, e.g., albendazole; ALB), which bind β-tubulin to disrupt microtubule polymerization, are one of two primary compound classes used to treat giardiasis. In most parasitic nematodes and fungi, BZ-resistance is caused by
Externí odkaz:
https://doaj.org/article/4dc27df364234738957f70e47311917c
Autor:
Annabel A Ferguson, Juan M Inclan-Rico, Dihong Lu, Sarah D Bobardt, LiYin Hung, Quentin Gouil, Louise Baker, Matthew E Ritchie, Aaron R Jex, Erich M Schwarz, Heather L Rossi, Meera G Nair, Adler R Dillman, De'Broski R Herbert
Publikováno v:
PLoS Pathogens, Vol 19, Iss 12, p e1011797 (2023)
The impact of the host immune environment on parasite transcription and fitness is currently unknown. It is widely held that hookworm infections have an immunomodulatory impact on the host, but whether the converse is true remains unclear. Immunity a
Externí odkaz:
https://doaj.org/article/8c2790ed821b4f769e8d8902d237e12a
Autor:
Samantha J. Emery-Corbin, Qiao Su, Swapnil Tichkule, Louise Baker, Ernest Lacey, Aaron R. Jex
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 16, Iss , Pp 162-173 (2021)
Benzimidazole-2-carbamate (BZ) compounds, including Albendazole (Alb), are one of just two drug classes approved to treat the gastrointestinal protist Giardia duodenalis. Benzimidazoles bind to the tubulin dimer interface overlapping the colchicine b
Externí odkaz:
https://doaj.org/article/4615c63208d94277b239d43239b2c1db
Autor:
John Allen, Zunera Zareen, Samantha Doyle, Laura Whitla, Zainab Afzal, Maria Stack, Orla Franklin, Andrew Green, Adam James, Timothy Ronan Leahy, Shoana Quinn, Basil Elnazir, John Russell, Sri Paran, Patrick Kiely, Edna Frances Roche, Ciara McDonnell, Louise Baker, Owen Hensey, Louise Gibson, Stephanie Kelly, Denise McDonald, Eleanor J. Molloy
Publikováno v:
Frontiers in Pediatrics, Vol 9 (2021)
Cerebral Palsy (CP) describes a heterogenous group of non-progressive disorders of posture or movement, causing activity limitation, due to a lesion in the developing brain. CP is an umbrella term for a heterogenous condition and is, therefore, descr
Externí odkaz:
https://doaj.org/article/3524829d07ee401ba481b48169e2afa4
Autor:
Brendan R E Ansell, Malcolm J McConville, Louise Baker, Pasi K Korhonen, Neil D Young, Ross S Hall, Cristian A A Rojas, Staffan G Svärd, Robin B Gasser, Aaron R Jex
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 9, Iss 12, p e0004261 (2015)
Giardia duodenalis is the most common gastrointestinal protozoan parasite of humans and a significant contributor to the global burden of both diarrheal disease and post-infectious chronic disorders. Although G. duodenalis can be cultured axenically,
Externí odkaz:
https://doaj.org/article/a818c6acc3c14b329cce233e8becaa6e
Autor:
Louise Baker, Andre M L Chitas, Carol A Hartley, Mauricio J C Coppo, Paola K Vaz, Andrew Stent, James R Gilkerson, Joanne M Devlin, Alison L Every
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e96563 (2014)
Alphaherpesviruses, which have co-evolved with their hosts for more than 200 million years, evade and subvert host immune responses, in part, by expression of immuno-modulatory molecules. Alphaherpesviruses express a single, broadly conserved chemoki
Externí odkaz:
https://doaj.org/article/e77ce459c55a4e2189fdf39e8217553b
Autor:
Kennedy Lushasi, Kirstyn Brunker, Malavika Rajeev, Elaine A Ferguson, Gurdeep Jaswant, Laurie Louise Baker, Roman Biek, Joel Changalucha, Sarah Cleaveland, Anna Czupryna, Anthony R Fooks, Nicodemus J Govella, Daniel T Haydon, Paul CD Johnson, Rudovick Kazwala, Tiziana Lembo, Denise Marston, Msanif Masoud, Matthew Maziku, Eberhard Mbunda, Geofrey Mchau, Ally Z Mohamed, Emmanuel Mpolya, Chanasa Ngeleja, Kija Ng'habi, Hezron Nonga, Kassim Omar, Kristyna Rysava, Maganga Sambo, Lwitiko Sikana, Rachel Steenson, Katie Hampson
Publikováno v:
eLife. 12
Background:Dog-mediated rabies is endemic across Africa causing thousands of human deaths annually. A One Health approach to rabies is advocated, comprising emergency post-exposure vaccination of bite victims and mass dog vaccination to break the tra
Autism spectrum disorder (ASD) is a common neurodevelopmental condition. The American Academy of Paediatrics and American Academy of Neurology do not recommend routine brain magnetic resonance imaging (MRI) in the assessment of ASD. The need for a br
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::27b0bcedb6f35d78af56958b2baa81df
https://doi.org/10.21203/rs.3.rs-2294626/v1
https://doi.org/10.21203/rs.3.rs-2294626/v1
Autor:
Swapnil Tichkule, Ernest Lacey, Qiao Su, Louise Baker, Aaron R. Jex, Samantha J. Emery-Corbin
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 16, Iss, Pp 162-173 (2021)
International Journal for Parasitology: Drugs and Drug Resistance
International Journal for Parasitology: Drugs and Drug Resistance
Benzimidazole-2-carbamate (BZ) compounds, including Albendazole (Alb), are one of just two drug classes approved to treat the gastrointestinal protist Giardia duodenalis. Benzimidazoles bind to the tubulin dimer interface overlapping the colchicine b
Autor:
Rebekah Henry, James Black, Chi Wen Tseng, Remy Schilperoort, Michael W. Thomas, Peter Kolotelo, Aaron R. Jex, Steve Einsiedel, Jonathan Schmidt, Nicolas D. Crosbie, Bruce R. Thorley, Louise Baker, Rachael Poon, David Thomas McCarthy, Jeroen Langeveld, Simon J. Wilson, Miao Wang, Christelle Schang, Kelly Hill, Peter J. Scales, Nijoy John, Baiqian Shi, Arash Zamyadi, Monica Nolan
Publikováno v:
Environmental Science & Technology
Environmental Science & Technology (Washington), 55(15)
Environmental Science & Technology (Washington), 55(15)
The shedding of pathogens by infected humans enables the use of sewage monitoring to conduct wastewater-based epidemiology (WBE). Although most WBE studies use data from large sewage treatment plants, timely data from smaller catchments are needed fo