Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Louise Afran"'
Autor:
Dumizulu Tembo, Visopo Harawa, Tam C. Tran, Louise Afran, Malcolm E. Molyneux, Terrie E. Taylor, Karl B. Seydel, Tonney Nyirenda, David G. Russell, Wilson Mandala
Publikováno v:
Malaria Journal, Vol 22, Iss 1, Pp 1-16 (2023)
Abstract Background Although pro-inflammatory cytokines are involved in the clearance of Plasmodium falciparum during the early stages of the infection, increased levels of these cytokines have been implicated in the pathogenesis of severe malaria. A
Externí odkaz:
https://doaj.org/article/52f1e7ea82e6445991b2942845a3a8ad
Autor:
Marah G. Chibwana, Thandeka Moyo-Gwete, Gaurav Kwatra, Jonathan Mandolo, Tandile Hermanaus, Thopisang Motlou, Nonkululeko Mzindle, Frances Ayres, Mphatso Chaponda, Godwin Tembo, Percy Mwenechanya, Ndaona Mitole, Chisomo Jassi, Raphael Kamng’ona, Louise Afran, David Mzinza, Henry C. Mwandumba, Stephen B. Gordon, Khuzwayo Jere, Shabir Madhi, Penny L. Moore, Robert S. Heyderman, Kondwani C. Jambo
Publikováno v:
BMC Medicine, Vol 20, Iss 1, Pp 1-10 (2022)
Abstract Background Binding and neutralising anti-Spike antibodies play a key role in immune defence against SARS-CoV-2 infection. Since it is known that antibodies wane with time and new immune-evasive variants are emerging, we aimed to assess the d
Externí odkaz:
https://doaj.org/article/b08b88ed1702406caaffe4634de9775e
Autor:
Dumizulu Tembo, Visopo Harawa, Tam C. Tran, Louise Afran, Malcolm E. Molyneux, Terrie E. Taylor, Karl B. Seydel, Tonney Nyirenda, David G. Russell, Wilson Mandala
Publikováno v:
Malaria Journal, Vol 22, Iss 1, Pp 1-2 (2023)
Externí odkaz:
https://doaj.org/article/6a99a5e40cc14c03bcae5a2380d8933e
Autor:
Christian Schmidt, Jeremie Fizet, Francesca Properzi, Mark Batchelor, Malin K. Sandberg, Julie A. Edgeworth, Louise Afran, Sammy Ho, Anjna Badhan, Steffi Klier, Jacqueline M. Linehan, Sebastian Brandner, Laszlo L. P. Hosszu, M. Howard Tattum, Parmjit Jat, Anthony R. Clarke, Peter C. Klöhn, Jonathan D. F. Wadsworth, Graham S. Jackson, John Collinge
Publikováno v:
Open Biology, Vol 5, Iss 12 (2015)
According to the protein-only hypothesis, infectious mammalian prions, which exist as distinct strains with discrete biological properties, consist of multichain assemblies of misfolded cellular prion protein (PrP). A critical test would be to produc
Externí odkaz:
https://doaj.org/article/d9df89cc5c84457ea1d505bc18d78e06
Autor:
Louise Afran, Kondwani C Jambo, Wilfred Nedi, David J C Miles, Anmol Kiran, Dominic H Banda, Ralph Kamg’ona, Dumizulu Tembo, Annette Pachnio, Eleni Nastouli, Brigit Ferne, Henry C Mwandumba, Paul Moss, David Goldblatt, Sarah Rowland-Jones, Adam Finn, Robert S Heyderman
Publikováno v:
The Journal of Infectious Diseases
Background Human immunodeficiency virus-exposed uninfected (HEU) infants are a rapidly expanding population in sub-Saharan Africa and are highly susceptible to encapsulated bacterial disease in the first year of life. The mechanism of this increased
Autor:
Joseph Kamtchum Tatuene, Louise Afran, Christine Kelly, Ntobeko A B Ntusi, Robert S. Heyderman, Henry C. Mwandumba, Laura A Benjamin, Joep J. van Oosterhout, Jacqueline Huwa, Ingrid Peterson, Kondwani C. Jambo, Marc Henrion, Sarah Pett
Publikováno v:
BMJ Open
IntroductionIn Sub-Saharan Africa, the rising rates of cerebrovascular and cardiovascular diseases (CBD/CVD) are intersecting with an ageing HIV-infected population. The widespread use of antiretroviral therapy (ART) may confer an additive risk and m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e025977d65553f6c279fd8804cea23a4
Autor:
Ingrid Peterson, Laura Benjamin, Henry Mwandumba, Ntobeko Ntusi, Peter Diggle, Kondwani Jambo, Louise Afran, Christine Kelly, Naveed Sattar, Iain McInnes, Rhian Touyz
UNSTRUCTURED Background: It is unclear why, compared to other settings, metabolic risk factors are low, yet risk of cardiovascular disease (CVD) and hypertension are high in Africa. One compelling possibility is that an on-going infectious disease bu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::509ed8b52c35e4b956a250ed91f3974d
https://doi.org/10.2196/preprints.8094
https://doi.org/10.2196/preprints.8094
Autor:
Louise Afran
Publikováno v:
Nature Reviews Immunology. 12:398-398