Phosphorylcholine Monoclonal Antibody Therapy Decreases Intraplaque Angiogenesis and Intraplaque Hemorrhage in Murine Vein Grafts

Autor: Fabiana Baganha, Thijs J. Sluiter, Rob C. M. de Jong, Louise A. van Alst, Hendrika A. B. Peters, J. Wouter Jukema, Mirela Delibegovic, Knut Pettersson, Paul H. A. Quax, Margreet R. de Vries

Publikováno v: International Journal of Molecular Sciences; Volume 23; Issue 21; Pages: 13662
International Journal of Molecular Sciences, 23(21). MDPI

Phosphorylcholine (PC) is one of the main oxLDL epitopes playing a central role in atherosclerosis, due to its atherogenic and proinflammatory effects. PC can be cleared by natural IgM antibodies and low levels of these antibodies have been associate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e224e87eaa483e2c309cedc49ec65e2b
https://doi.org/10.3390/ijms232113662