Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Louise A. Scrocchi"'
Autor:
C. Bruce Verchere, Mark Lipsett, Louise A. Scrocchi, Paul E. Fraser, Lawrence Rosenberg, Ziliang Ao, Marika A. Younker, Kathryn J. Potter, Garth L. Warnock
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 1790:566-574
Background Amyloid fibrils created by misfolding and aggregation of proteins are a major pathological feature in a variety of degenerative diseases. Therapeutic approaches including amyloid vaccines and anti-aggregation compounds in models of amyloid
Publikováno v:
Letters in Peptide Science. 10:545-551
Human islet amyloid polypeptide (IAPP) is the major component of amyloid deposits found in the pancreas of over 90% of all cases of type-2 diabetes. Although it may be a secondary event in the etiology of diabetes, the accumulation of insoluble IAPP
Publikováno v:
Journal of Structural Biology. 141:218-227
We have examined a series of overlapping peptide fragments from the 8–20 region of human islet amyloid polypeptide (IAPP) with the objective of defining the smallest fibril-forming domain. Peptide fragments corresponding to LANFLV (residues 12–17
Autor:
Louise A. Scrocchi, Franco J. Vaccarino, Sylvia L. Asa, Jennifer L. Shin, Neil J. MacLusky, Julie Kim, Daniel J. Drucker, Sonya Cook
Publikováno v:
Endocrinology. 141:752-762
Glucagon-like peptide-1 (GLP-1), a potent regulator of glucose homeostasis, is also produced in the central nervous system, where GLP-1 has been implicated in the neuroendocrine control of hypothalamic-pituitary function, food intake, and the respons
Autor:
Elizabeth Schaerer, Louise A. Scrocchi, Véronique Serre, Bernard Thorens, Wanda Dolci, Daniel J. Drucker, Shimon Efrat
Publikováno v:
Endocrinology. 139:4448-4454
The effect of exendin-(9–39), a described antagonist of the glucagon-like peptide-1 (GLP-1) receptor, was evaluated on the formation of cAMP- and glucose-stimulated insulin secretion (GSIS) by the conditionally immortalized murine βTC-Tet cells. T
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 60:163-169
Marked changes in mouse corticosteroid-binding globulin (CBG) gene expression in the liver and kidney occur postnatally. To study the influence of glucocorticoids on the initiation of mouse CBG biosynthesis in these tissues during the first two weeks
Autor:
Neil R. Cashman, Louise A. Scrocchi, Vivian Lee, Melissa Osborne, Hui Chen, Marty Lehto, Elizabeth Karaskov, Michael Sasner, Bart Kus, Marni D. Uger, Cathleen M. Lutz
Publikováno v:
Alzheimer's & Dementia. 6
Autor:
Jing Wang, Cheryl L. Wellington, Neil R. Cashman, Leslie I. Grad, James Donkin, Megan A. O'Neill, Louise A. Scrocchi
Publikováno v:
Alzheimer's & Dementia. 6
Autor:
Vivian Lee, Marni D. Uger, Hui Chen, Elizabeth Karaskov, Bart Kus, Neil R. Cashman, Marty Lehto, Louise A. Scrocchi, Veronica Ciolfi
Publikováno v:
Alzheimer's & Dementia. 5
Autor:
Pieter Biessels, David S. Bell, M. James Phillips, Nancy Ng, Laisum Fung, Ian D. McGilvray, Gord Adamson, Caroline Woods, Reginald M. Gorczynski, Louise A. Scrocchi, Max Ma, Adam Levy, Cheryl Koscik, William He, Steve Brookes, Andrea Rowe, Gary A. Levy, Anand Ghanekar
Publikováno v:
Hepatology (Baltimore, Md.)
Side effects of interferon–ribavirin combination therapy limit the sustained viral response achievable in hepatitis C virus (HCV) patients. Coupling ribavirin to macromolecular carriers that target the drug to the liver would reduce systemic compli