Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Louise A. Rooney"'
Autor:
Maciej Daniszewski, Quan Nguyen, Hun S. Chy, Vikrant Singh, Duncan E. Crombie, Tejal Kulkarni, Helena H. Liang, Priyadharshini Sivakumaran, Grace E. Lidgerwood, Damián Hernández, Alison Conquest, Louise A. Rooney, Sophie Chevalier, Stacey B. Andersen, Anne Senabouth, James C. Vickers, David A. Mackey, Jamie E. Craig, Andrew L. Laslett, Alex W. Hewitt, Joseph E. Powell, Alice Pébay
Publikováno v:
iScience, Vol 7, Iss , Pp 30-39 (2018)
Summary: We assessed the pluripotency of human induced pluripotent stem cells (iPSCs) maintained on an automated platform using StemFlex and TeSR-E8 media. Analysis of transcriptome of single cells revealed similar expression of core pluripotency gen
Externí odkaz:
https://doaj.org/article/7a57b9886f4c465e9568b2e61af1aab8
Autor:
Helena Liang, Anthony L. Cook, Damián Hernández, Maciej Daniszewski, Alex W. Hewitt, Lerna Gulluyan, Louise A. Rooney, Alice Pébay
Publikováno v:
Stem Cell Reviews and Reports. 18:718-731
Apolipoprotein E (APOE) is the most important susceptibility gene for late onset of Alzheimer's disease (AD), with the presence of APOE-e4 associated with increased risk of developing AD. Here, we reprogrammed human fibroblasts from individuals with
Autor:
Lisa S. Kearns, Helena Liang, Nona Farbehi, Xikun Han, Alex W. Hewitt, Drew Neavin, Grace E. Lidgerwood, Stuart MacGregor, M Isabel G Lopez Sanchez, Lerna Gulluyan, Damián Hernández, David A. Mackey, Angela Steinmann, Linda Clarke, Vivek Gupta, Louise A. Rooney, Joseph E. Powell, Alice Pébay, Chia-Ling Chan, Robyn H. Guymer, Ran Zhang, Joao A. Paulo, Maciej Daniszewski, Guy Bylsma, Uyen Nguyen, Vikkitharan Gnanasambandapillai, Rachael Zekanovic, Anne Senabouth, Nitin Verma, Mehdi Mirzaei
Publikováno v:
Nature communications. 13(1)
Induced pluripotent stem cells generated from patients with geographic atrophy as well as healthy individuals were differentiated to retinal pigment epithelium (RPE) cells. By integrating transcriptional profiles of 127,659 RPE cells generated from 4
Autor:
Craig Jee, Gnanasambandapillai, Stuart MacGregor, David A. Mackey, Damián Hernández, Xikun Han, Alex W. Hewitt, Uyen Nguyen, Joseph E. Powell, Lisa S. Kearns, Helena Liang, Nona Farbehi, Shiang Y. Lim, Clarke Je, Chia-Ling Chan, Grace E. Lidgerwood, Alice Pébay, Stuart L. Graham, Lerna Gulluyan, Maciej S. Daniszewski, Louise A. Rooney, Anne Senabouth, Emmanuelle Souzeau, Jarmon G Lees, Linda Clarke, Priyadharshini Sivakumaran, Rachael A. McCloy
To assess the transcriptomic profile of disease-specific cell populations, fibroblasts from patients with primary open-angle glaucoma (POAG) were reprogrammed into induced pluripotent stem cells (iPSCs) before being differentiated into retinal organo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fd62af0be4c082bac473a4af4b066ba5
https://doi.org/10.1101/2021.07.14.452417
https://doi.org/10.1101/2021.07.14.452417
Autor:
Damián, Hernández, Louise A, Rooney, Maciej, Daniszewski, Lerna, Gulluyan, Helena H, Liang, Anthony L, Cook, Alex W, Hewitt, Alice, Pébay
Publikováno v:
Stem cell reviews and reports. 18(2)
Apolipoprotein E (APOE) is the most important susceptibility gene for late onset of Alzheimer's disease (AD), with the presence of APOE-ε4 associated with increased risk of developing AD. Here, we reprogrammed human fibroblasts from individuals with
Autor:
Maciej Daniszewski, Damián Hernández, Anthony L. Cook, Helena Liang, Lerna Gulluyan, Louise A. Rooney, Alex W. Hewitt, Alice Pébay
SummaryApolipoprotein E (APOE) is the most important susceptibility gene for late onset of Alzheimer’s disease, with the presence of APOE-ε4 associated with increased risk of developing Alzheimer’s disease. Here, we reprogrammed human fibroblast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a2a2123a3f6753040b3d9708e93002d
https://doi.org/10.1101/2020.11.30.405654
https://doi.org/10.1101/2020.11.30.405654
Publikováno v:
The Routledge Handbook of Visual Impairment ISBN: 9781315111353
Human pluripotent stem cells (hPSCs) hold great promise for human therapies including for treatment of eye-related disease. Given that hPSCs can differentiate into any cell type of the body, they could potentially be used for cell therapies or as pla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f16b21388fee71b62d7fc611f31cb1de
https://doi.org/10.4324/9781315111353-24
https://doi.org/10.4324/9781315111353-24
Autor:
Damián Hernández, Anne Senabouth, Vikrant Singh, David A. Mackey, Tejal Kulkarni, Duncan E. Crombie, Helena Liang, Stacey B. Andersen, Andrew L. Laslett, Hun S. Chy, Joseph E. Powell, Sophie Chevalier, Maciej Daniszewski, Alex W. Hewitt, Grace E. Lidgerwood, James C. Vickers, Jamie E Craig, Louise A. Rooney, Priyadharshini Sivakumaran, Alison Conquest, Quan Nguyen, Alice Pébay
Publikováno v:
iScience, Vol 7, Iss, Pp 30-39 (2018)
Summary: We assessed the pluripotency of human induced pluripotent stem cells (iPSCs) maintained on an automated platform using StemFlex and TeSR-E8 media. Analysis of transcriptome of single cells revealed similar expression of core pluripotency gen
Autor:
Tejal Kulkarni, Helena Liang, Quan Nguyen, Duncan E. Crombie, Anne Senabouth, Alex W. Hewitt, Jamie E Craig, Hun S. Chy, Sophie Chevalier, Maciej Daniszewski, Andrew L. Laslett, Damián Hernández, Stacey B. Andersen, Grace E. Lidgerwood, James C. Vickers, Louise A. Rooney, David A. Mackey, Alice Pébay, Joseph E. Powell, Alison Conquest, Vikrant Singh
Publikováno v:
SSRN Electronic Journal.
We assessed the pluripotency of human induced pluripotent stem cells (iPSCs) maintained on an automated platform using StemFlexTM and TeSRTM-E8TM media. Analysis of transcriptome of single cells revealed similar expression of core pluripotency genes,
Autor:
Andrew J. Morris, Maciej Daniszewski, Alex W. Hewitt, Robyn H. Guymer, Penelope J Allen, Paul P. Connell, Shiang Y. Lim, Helena Liang, Damián Hernández, Alison Conquest, Alice Pébay, Grace E. Lidgerwood, Louise A. Rooney
Publikováno v:
Biochimica et biophysica acta. Molecular and cell biology of lipids. 1863(7)
The human retina is a complex structure of organised layers of specialised cells that support the transmission of light signals to the visual cortex. The outermost layer of the retina, the retinal pigment epithelium (RPE), forms part of the blood ret