Zobrazeno 1 - 10
of 98
pro vyhledávání: '"Louise, Warnich"'
Autor:
Ananyo Choudhury, Michèle Ramsay, Scott Hazelhurst, Shaun Aron, Soraya Bardien, Gerrit Botha, Emile R. Chimusa, Alan Christoffels, Junaid Gamieldien, Mahjoubeh J. Sefid-Dashti, Fourie Joubert, Ayton Meintjes, Nicola Mulder, Raj Ramesar, Jasper Rees, Kathrine Scholtz, Dhriti Sengupta, Himla Soodyall, Philip Venter, Louise Warnich, Michael S. Pepper
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
African populations show a high level of genetic diversity and extensive regional admixture. Here, the authors sequence the whole genomes of 24 South African individuals of different ethnolinguistic origin and find substantive genomic divergence betw
Externí odkaz:
https://doaj.org/article/8fda92929c8c49e5a1b6b54ed223b65f
Publikováno v:
Frontiers in Genetics, Vol 10 (2019)
Despite advances in pharmacogenetics, the majority of heritability for treatment response cannot be explained by common variation, suggesting that factors such as epigenetics may play a key role. Regulatory genes, such as those involved in DNA methyl
Externí odkaz:
https://doaj.org/article/30e95fb1cbba4eacb5be57d3a58cb141
Autor:
Anil K. Malhotra, Todd Lencz, Louise Warnich, Kevin S. O’Connell, Robin Emsley, Nathaniel W. McGregor
Publikováno v:
The Pharmacogenomics Journal. 19:109-114
Voltage-gated calcium channels have been implicated in schizophrenia aetiology; however, little is known about their involvement in antipsychotic treatment response. This study investigated variants within the calcium channel subunit genes for associ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed86ab4191d31b9309a216b346b71600
https://doi.org/10.1038/s41397-018-0033-5
https://doi.org/10.1038/s41397-018-0033-5
Autor:
Nicole Thompson, Kevin S. O’Connell, Lize van der Merwe, Louise Warnich, Robin Emsley, Nathaniel W. McGregor
Publikováno v:
Psychiatry Research. 262:141-148
Antipsychotics remain the most effective, and wide used option for ameliorating the symptoms of schizophrenia. However, inter-individual differences in treatment outcome are vast and suggest a role for genetic and environmental factors in affording f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17fcab02f460828653b500db36c0c2dc
https://doi.org/10.1016/j.psychres.2018.01.044
https://doi.org/10.1016/j.psychres.2018.01.044
Autor:
Gerrit Botha, Michael S. Pepper, Nicola Mulder, Kathrine Elizabeth Scholtz, Alan Christoffels, Emile R. Chimusa, Raj Ramesar, Ananyo Choudhury, Ayton Meintjes, Michèle Ramsay, Fourie Joubert, Scott Hazelhurst, Louise Warnich, Soraya Bardien, Shaun Aron, Jasper Rees, Mahjoubeh J. Sefid-Dashti, Dhriti Sengupta, Philip Venter, Junaid Gamieldien, Himla Soodyall
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Nature Communications
Nature Communications
The Southern African Human Genome Programme is a national initiative that aspires to unlock the unique genetic character of southern African populations for a better understanding of human genetic diversity. In this pilot study the Southern African H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::490bf22bbd1f09044e925f504f5ea227
https://doaj.org/article/8fda92929c8c49e5a1b6b54ed223b65f
https://doaj.org/article/8fda92929c8c49e5a1b6b54ed223b65f
Publikováno v:
Frontiers in Genetics, Vol 10 (2019)
Despite advances in pharmacogenetics, the majority of heritability for treatment response cannot be explained by common variation, suggesting that factors such as epigenetics may play a key role. Regulatory genes, such as those involved in DNA methyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56de3016d880be0c6bfc55d2f06e6d21
https://www.frontiersin.org/article/10.3389/fgene.2019.00641/full
https://www.frontiersin.org/article/10.3389/fgene.2019.00641/full
Autor:
Shareefa Dalvie, Caroline M. Nievergelt, Raj Ramesar, Louise Warnich, Nathaniel W. McGregor, Kevin S. O’Connell, Nastassja Koen, Dan J. Stein
Publikováno v:
OMICS: A Journal of Integrative Biology. 20:557-564
Mental disorders represent a major public health burden worldwide. This is likely to rise in the next decade, with the highest increases predicted to occur in low- and middle-income countries. Current psychotropic medication treatment guidelines focu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cab57fafbb7d6a2fe27eb5c619e25eb6
https://doi.org/10.1089/omi.2016.0110
https://doi.org/10.1089/omi.2016.0110
Autor:
Louise Warnich, Nelis Grobbelaar, Galen E.B. Wright, Britt I. Drögemöller, Lize van der Merwe, Carola R Röhrich, Nathaniel W. McGregor, Ogechi Ikediobi
Publikováno v:
AIDS Research and Human Retroviruses. 32:529-538
Long-term exposure to efavirenz (EFV) measured in hair samples may predict response to antiretroviral treatment (ART). Polymorphisms in CYP2B6 are known to alter EFV levels. The aim of this study was to assess the relationship between CYP2B6 genotype
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1427f64a5c4997a009ac1506a79c8d16
https://doi.org/10.1089/aid.2015.0048
https://doi.org/10.1089/aid.2015.0048
Autor:
Can Hekim, Eyup Ilker Saygili, Collet Dandara, Oylum Tanrıöver, Ümit Karakaş, Laszlo Endrenyi, Türkay Dereli, Yusuf Ziya Yıldırım, Farah Huzair, Adrián LLerena, Collen Masimirembwa, Güner Dağlı, Yavuz Coşkun, Kıvanç Güngör, Deniz Vuruşkan, Alexander Borda-Rodriguez, Alexandros G. Georgakilas, Sabit Kimyon, Eleni Aklillu, Bircan Günbulut, Levent Elbeyli, Nezih Hekim, İbrahim Ömer Barlas, Ambroise Wonkam, Louise Warnich, Filiz Aydogan Boschele, Volkan İhsan Töre, Türkan Uğur Dai, Alper Mete, Asım Güzelbey, Ahmet Sınav, Can Polat Eyigün, Peşvin Sancar, Ismet Yilmaz, David Tyfield, Biaoyang Lin, Zafer Cetin, Salih Murat Akkın, Enes Coşkun, Ruth McNally, Wei Wang, Sanjeeva Srivastava, Alaa Abou-Zeid, Lotte Maria Gertruda Steuten
Publikováno v:
OMICS: A Journal of Integrative Biology. 20:259-262
WOS: 000374760800008
27093110
27093110
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4d2fe4a44137fb91c44c5918612a0f6
https://doi.org/10.1089/omi.2016.0038
https://doi.org/10.1089/omi.2016.0038
Autor:
Kevin Sean, O'Connell, Nathaniel Wade, McGregor, Robin, Emsley, Soraya, Seedat, Louise, Warnich
Publikováno v:
Frontiers in Genetics
Despite advances in pharmacogenetics, the majority of heritability for treatment response cannot be explained by common variation, suggesting that factors such as epigenetics may play a key role. Regulatory genes, such as those involved in DNA methyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ec9039e97f197a755ef7d79f52da130a
https://pubmed.ncbi.nlm.nih.gov/31354789
https://pubmed.ncbi.nlm.nih.gov/31354789