Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Louisa Wirthlin"'
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e75012 (2013)
There is compelling in vivo evidence from reports on human genetic mutations and transgenic mice that some microRNAs (miRNAs) play an important functional role in regulating skeletal development and growth. A number of published in vitro studies also
Externí odkaz:
https://doaj.org/article/ab152aa1e57c48898994f929f955fa62
Publikováno v:
Matrix Biology. 36:51-63
This study describes a new mechanism controlling the production of alternatively spliced isoforms of type II procollagen (Col2a1) in vivo. During chondrogenesis, precursor chondrocytes predominantly produce isoforms containing alternatively spliced e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71ad3b5d85150686c465b2cf8f7366cb
https://doi.org/10.1016/j.matbio.2014.04.004
https://doi.org/10.1016/j.matbio.2014.04.004
Publikováno v:
Matrix Biology. 65:119-120
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::99f60ebdbcd5100d405cdd373475c964
https://doi.org/10.1016/j.matbio.2018.01.008
https://doi.org/10.1016/j.matbio.2018.01.008
Autor:
Russell J. Fernandes, Louisa Wirthlin, Renate M. Lewis, Soumya Ravindran, Geoffrey Traeger, Audrey McAlinden
Publikováno v:
Matrix Biology. 31:214-226
The present study describes the generation of a knock-in mouse model to address the role of type II procollagen (Col2a1) alternative splicing in skeletal development and maintenance. Alternative splicing of Col2a1 precursor mRNA is a developmentally-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5043e012b23a1159b7e4c0fbf6aab85
https://doi.org/10.1016/j.matbio.2011.12.004
https://doi.org/10.1016/j.matbio.2011.12.004
Autor:
Louisa Wirthlin, Carole Vogler, Todd E. Meyerrose, Kevin K. Ohlemiller, Marie S. Roberts, Jan A. Nolta, Mark S. Sands
Publikováno v:
Stem Cells. 26:1713-1722
Bone marrow-derived mesenchymal stem cells (MSCs) are a promising platform for cell- and gene-based treatment of inherited and acquired disorders. We recently showed that human MSCs distribute widely in a murine xenotransplantation model. In the curr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2301d287e1fea73053b166e74794d7c
https://doi.org/10.1634/stemcells.2008-0008
https://doi.org/10.1634/stemcells.2008-0008
Autor:
Sarah A. Hohm, David A. Hess, William C. Eades, Louisa Wirthlin, Jan A. Nolta, Timothy P. Craft, Michael H. Creer, Mark S. Sands, Ping Zhou
Publikováno v:
Stem Cells. 26:611-620
Transplanted adult progenitor cells distribute to peripheral organs and can promote endogenous cellular repair in damaged tissues. However, development of cell-based regenerative therapies has been hindered by the lack of preclinical models to effici
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd47c6b2be3dfd9e0a49f5e975a36811
https://doi.org/10.1634/stemcells.2007-0429
https://doi.org/10.1634/stemcells.2007-0429
Autor:
John F. DiPersio, Laura Todt, Louisa Wirthlin, Ryan Lahey, Steven M. Devine, Jesper Bonde, David A. Hess, Timothy P. Craft, Sarah A. Hohm, Jan A. Nolta
Publikováno v:
Biology of Blood and Marrow Transplantation. 13(4):398-411
AMD3100 inhibits the interaction between SDF-1 and CXCR4, and rapidly mobilizes hematopoietic progenitors for clinical transplantation. However, the repopulating function of human cells mobilized with AMD3100 has not been characterized in comparison
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::106d251e76be9424b5b2fac841a3d064
Autor:
J. Chris Eagon, Todd E. Meyerrose, Mark S. Sands, Louisa Wirthlin, Marc A. Hedrick, Leonard D. Shultz, Daniel A. De Ugarte, A. Alex Hofling, Phillip E. Herrbrich, Jan A. Nolta, Taylor D. Cordonnier
Publikováno v:
Stem Cells. 25:220-227
The potential for human adipose-derived mesenchymal stem cells (AMSC) to traffic into various tissue compartments was examined using three murine xenotransplantation models: nonobese diabetic/severe combined immunodeficient (NOD/SCID), nude/NOD/SCID,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80c3e41a577ebfe51a7c30273ae92895
https://doi.org/10.1634/stemcells.2006-0243
https://doi.org/10.1634/stemcells.2006-0243
Autor:
Michael H. Creer, David A. Hess, Sarah A. Hohm, Timothy P. Craft, Phillip E. Herrbrich, Ryan Lahey, Jan A. Nolta, Louisa Wirthlin, William C. Eades
Publikováno v:
Blood. 107:2162-2169
The development of novel cell-based therapies requires understanding of distinct human hematopoietic stem and progenitor cell populations. We recently isolated reconstituting hematopoietic stem cells (HSCs) by lineage depletion and purification based
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e9cc6c1d7c6cf63902eb1f360b368e0
https://doi.org/10.1182/blood-2005-06-2284
https://doi.org/10.1182/blood-2005-06-2284
Autor:
Phillip E. Herrbrich, Timothy P. Craft, Todd E. Meyerrose, Michael H. Creer, David A. Hess, Jan A. Nolta, Louisa Wirthlin
Publikováno v:
Blood. 104:1648-1655
Human hematopoietic stem cells (HSCs) are commonly purified by the expression of cell surface markers such as CD34. Because cell phenotype can be altered by cell cycle progression or ex vivo culture, purification on the basis of conserved stem cell f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::724b02f3780f265c8f4ab3db1744c844
https://doi.org/10.1182/blood-2004-02-0448
https://doi.org/10.1182/blood-2004-02-0448