The Impact of Upcoming Treatments in Huntington’s Disease: Resource Capacity Limitations and Access to Care Implications

Autor: Marsha Pelletier, Jean-Marc Burgunder, Marco Pedrazzoli, Kopano Mukelabai, Louisa Townson, Marina Ponomareva, Anna-Lena Nordström, Ralf Reilmann, Mark Guttman, Aaron Levine

Publikováno v: Guttman, Mark; Pedrazzoli, Marco; Ponomareva, Marina; Pelletier, Marsha; Townson, Louisa; Mukelabai, Kopano; Levine, Aaron; Nordström, Anna-Lena; Reilmann, Ralf; Burgunder, Jean-Marc (2021). The Impact of Upcoming Treatments in Huntington's Disease: Resource Capacity Limitations and Access to Care Implications. Journal of Huntington's disease, 10(2), pp. 303-311. IOS Press 10.3233/JHD-200462
Journal of Huntington's Disease

BACKGROUND The most advanced disease-modifying therapies (DMTs) in development for Huntington's disease (HD) require intrathecal (IT) administration, which may create or exacerbate bottlenecks in resource capacity. OBJECTIVE To understand the readine

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f11222ca8d9002ba30c2b786c16c27e
https://doi.org/10.3233/jhd-200462

Diffuse noxious inhibitory controls and nerve injury

Autor: Ryan Patel, Louisa Townson, Anthony H. Dickenson, Leonor Gonçalves, Kirsty Bannister

Publikováno v: Pain. 156:1803-1811

Diffuse noxious inhibitory controls (DNICs) utilize descending inhibitory controls through poorly understood brain stem pathways. The human counterpart, conditioned pain modulation, is reduced in patients with neuropathy aligned with animal data show

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8c27e6c4ae436e6d3b060b016824062
https://doi.org/10.1097/j.pain.0000000000000240