Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Louisa S Chard Dunmall"'
Autor:
Jun Wang, Peng Liu, Nicholas Lemoine, Yaohe Wang, Louisa S Chard Dunmall, Carmela Di Gioia, Claude Chelala, Renato Brito Baleeiro, Ai Nagano, Lauren Cutmore, Lydon Wainaina Nyambura, Peter Walden
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 8 (2023)
Background Triple-negative breast cancer (TNBC) corresponds to approximately 20% of all breast tumors, with a high propensity for metastasis and a poor prognosis. Because TNBC displays a high mutational load compared with other breast cancer types, a
Externí odkaz:
https://doaj.org/article/4a364f55984e4ee2890cd336874dee1d
Autor:
Yangyang Jia, Yanru Wang, Louisa S Chard Dunmall, Nicholas R. Lemoine, Pengju Wang, Yaohe Wang
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Cancer immunotherapy (CIT) has emerged as an exciting new pillar of cancer treatment. Although benefits have been achieved in individual patients, the overall response rate is still not satisfactory. To address this, an ideal preclinical animal model
Externí odkaz:
https://doaj.org/article/41c87dac90124c76b9c6c211a853f0dd
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Many energy metabolism pathways exist in cancer, including glycolysis, amino acid metabolism, fatty acid oxidation, and mitochondrial respiration. Tumor cells mainly generate energy through glycolysis to maintain growth and biosynthesis of tumor cell
Externí odkaz:
https://doaj.org/article/b2f4d10882ca46df85686eeeb6035f60
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 5 (2022)
Tumor cells manipulate the local environment in which they grow, creating a tumor microenvironment (TME) that promotes tumor survival and metastasis. The TME is an extremely complex environment rich in immunosuppressive cells and cytokines. Various m
Externí odkaz:
https://doaj.org/article/ee9e34c281bd47568d1127c5cd2cb33e
Autor:
Jahangir Ahmed, Ming Yuan, Zhongxian Zhang, Nicholas Lemoine, Yaohe Wang, Giulia Marelli, Louisa S Chard Dunmall, Carmela Di Gioia, Jinxin Miao, Zhenguo Cheng, Rathi Gangeswaran
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 1 (2021)
Background Pancreatic cancer remains one of the most lethal cancers and is refractory to immunotherapeutic interventions. Oncolytic viruses are a promising new treatment option, but current platforms demonstrate limited efficacy, especially for inacc
Externí odkaz:
https://doaj.org/article/24cba0290a804cf7b8b7cccfb572b712
Autor:
Yijie Sun, Zhe Zhang, Chenglin Zhang, Na Zhang, Pengju Wang, Yongchao Chu, Louisa S. Chard Dunmall, Nicholas R. Lemoine, Yaohe Wang
Publikováno v:
Molecular Therapy: Oncolytics, Vol 26, Iss , Pp 105-119 (2022)
Glioblastoma (GBM) is the most common primary malignant tumor in the brain, accounting for 51.4% of all primary brain tumors. GBM has a highly immunosuppressive tumor microenvironment (TME) and, as such, responses to immunotherapeutic strategies are
Externí odkaz:
https://doaj.org/article/8f09c6d055de4f21a20473329d2488c7
Autor:
Dujuan Cao, Qianqian Song, Junqi Li, Louisa S. Chard Dunmall, Yuanyuan Jiang, Bin Qin, Jianyao Wang, Haoran Guo, Zhenguo Cheng, Zhimin Wang, Nicholas R. Lemoine, Shuangshuang Lu, Yaohe Wang
Publikováno v:
Molecular Therapy: Oncolytics, Vol 25, Iss , Pp 264-275 (2022)
Immunotherapies, such as immune checkpoint inhibitors (ICIs) and chimeric antigen receptor-T (CAR-T) cells, are only efficient in a small proportion of tumor patients. One of the major reasons for this is the lack of immune cell infiltration and acti
Externí odkaz:
https://doaj.org/article/6aa4fe715b2b437d9107fedce2733a9f
Autor:
Zhe Zhang, Shuangshuang Lu, Louisa S. Chard Dunmall, Zhizhong Wang, Zhenguo Cheng, Zhongxian Zhang, Wenli Yan, Yongchao Chu, Dongling Gao, Na Wang, Yang Li, Jiwei Wang, Yuenan Li, Yupei Ji, Danyang Shan, Keke Li, Panpan Wang, Yunshu Dong, Jianzeng Dong, Nick R. Lemoine, Duanqing Pei, Lirong Zhang, Yaohe Wang
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Lung cancer is one of the most commonly diagnosed cancer and despite therapeutic advances, mortality remains high. The long period of clinical latency associated with lung cancer provides an ideal window of opportunity to administer vaccines to at-ri
Externí odkaz:
https://doaj.org/article/0732dd0f70924129bc3cb791a7c0317e
Autor:
Zifang Zhang, Chunyang Zhang, Jinxin Miao, Zhizhong Wang, Zhimin Wang, Zhenguo Cheng, Pengju Wang, Louisa S. Chard Dunmall, Nicholas R. Lemoine, Yaohe Wang
Publikováno v:
Cells, Vol 9, Iss 11, p 2438 (2020)
Esophageal squamous cell carcinoma (ESCC) is one of the most lethal cancers in China and existing therapies have been unable to significantly improve prognosis. Oncolytic adenoviruses (OAds) are novel promising anti-tumor drugs and have been evaluate
Externí odkaz:
https://doaj.org/article/dc93265efae94aae9af182521f7c0550
Autor:
Renato B. Baleeiro, Christian J. Bouwens, Peng Liu, Carmela Di Gioia, Louisa S. Chard Dunmall, Ai Nagano, Rathistevy Gangeswaran, Claude Chelala, Hemant M. Kocher, Nicholas R. Lemoine, Yaohe Wang
Publikováno v:
Oncoimmunology. 11(1)
MHC class II expression is a hallmark of professional antigen-presenting cells and key to the induction of CD4+ T helper cells. We found that these molecules are ectopically expressed on tumor cells in a large proportion of patients with pancreatic d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69a3eef5df08083cc8add1172e514f31
https://pubmed.ncbi.nlm.nih.gov/35655709
https://pubmed.ncbi.nlm.nih.gov/35655709